TopFIND 4.0

P76578: Alpha-2-macroglobulin {ECO:0000303|PubMed:15186489, ECO:0000303|PubMed:18697741}

General Information

Protein names
- Alpha-2-macroglobulin {ECO:0000303|PubMed:15186489, ECO:0000303|PubMed:18697741}
- ECAM {ECO:0000303|PubMed:18697741}
Gene names yfhM
Organism Escherichia coli
Protease Family
Protease ID I39.008
Chromosome location
UniProt ID P76578

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKKLRVAACM LMLALAGCDN NDNAPTAVKK DAPSEVTKAA SSENASSAKL SVPERQKLAQ 
        70         80         90        100        110        120 
QSAGKVLTLL DLSEVQLDGA ATLVLTFSIP LDPDQDFSRV IHVVDKKSGK VDGAWELSDN 
       130        140        150        160        170        180 
LKELRLRHLE PKRDLIVTIG KEVKALNNAT FSKDYEKTIT TRDIQPSVGF ASRGSLLPGK 
       190        200        210        220        230        240 
VVEGLPVMAL NVNNVDVNFF RVKPESLPAF ISQWEYRNSL ANWQSDKLLQ MADLVYTGRF 
       250        260        270        280        290        300 
DLNPARNTRE KLLLPLGDIK PLQQAGVYLA VMNQAGRYDY SNPATLFTLS DIGVSAHRYH 
       310        320        330        340        350        360 
NRLDIFTQSL ENGAAQQGIE VSLLNEKGQT LTQATSDAQG HVQLENDKNA ALLLARKDGQ 
       370        380        390        400        410        420 
TTLLDLKLPA LDLAEFNIAG APGYSKQFFM FGPRDLYRPG ETVILNGLLR DADGKALPNQ 
       430        440        450        460        470        480 
PIKLDVIKPD GQVLRSVVSQ PENGLYHFTW PLDSNAATGM WHIRANTGDN QYRMWDFHVE 
       490        500        510        520        530        540 
DFMPERMALN LTGEKTPLTP KDEVKFSVVG YYLYGAPANG NTLQGQLFLR PLREAVSALP 
       550        560        570        580        590        600 
GFEFGDIAAE NLSRTLDEVQ LTLDDKGRGE VSTESQWKET HSPLQVIFQG SLLESGGRPV 
       610        620        630        640        650        660 
TRRAEQAIWP ADALPGIRPQ FASKSVYDYR TDSTVKQPIV DEGSNAAFDI VYSDAQGVKK 
       670        680        690        700        710        720 
AVSGLQVRLI RERRDYYWNW SEDEGWQSQF DQKDLIENEQ TLDLKADETG KVSFPVEWGA 
       730        740        750        760        770        780 
YRLEVKAPNE AVSSVRFWAG YSWQDNSDGS GAVRPDRVTL KLDKASYRPG DTIKLHIAAP 
       790        800        810        820        830        840 
TAGKGYAMVE SSEGPLWWQE IDVRAQGLDL TIPVDKTWNR HDLYLSTLVV RPGDKSRSAT 
       850        860        870        880        890        900 
PKRAVGVLHL PLGDENRRLD LALETPAKMR PNQPLTVKIK ASTKNGEKPK QVNVLVSAVD 
       910        920        930        940        950        960 
SGVLNITDYV TPDPWQAFFG QKRYGADIYD IYGQVIEGQG RLAALRFGGD GDELKRGGKP 
       970        980        990       1000       1010       1020 
PVNHVNIVVQ QALPVTLNEQ GEGSVTLPIG DFNGELRVMA QAWTADDFGS NESKVIVAAP 
      1030       1040       1050       1060       1070       1080 
VIAELNMPRF MASGDTSRLT LDITNLTDKP QKLNVALTAS GLLELVSDSP AAVELAPGVR 
      1090       1100       1110       1120       1130       1140 
TTLFIPVRAL PGYGDGEIQA TISGLALPGE TVADQHKQWK IGVRPAFPAQ TVNYGTALQP 
      1150       1160       1170       1180       1190       1200 
GETWAIPADG LQNFSPVTLE GQLLLSGKPP LNIARYIKEL KAYPYGCLEQ TASGLFPSLY 
      1210       1220       1230       1240       1250       1260 
TNAAQLQALG IKGDSDEKRR ASVDIGISRL LQMQRDNGGF ALWDKNGDEE YWLTAYVMDF 
      1270       1280       1290       1300       1310       1320 
LVRAGEQGYS VPTDAINRGN ERLLRYLQDP GMMSIPYADN LKASKFAVQS YAALVLARQQ 
      1330       1340       1350       1360       1370       1380 
KAPLGALREI WEHRADAASG LPLLQLGVAL KTMGDATRGE EAIALALKTP RNSDERIWLG 
      1390       1400       1410       1420       1430       1440 
DYGSSLRDNA LMLSLLEENK LLPDEQYTLL NTLSQQAFGE RWLSTQESNA LFLAARTIQD 
      1450       1460       1470       1480       1490       1500 
LPGKWQAQTS FSAEQLTGEK AQNSNLNSDQ LVTLQVSNSG DQPLWLRMDA SGYPQSAPLP 
      1510       1520       1530       1540       1550       1560 
ANNVLQIERH ILGTDGKSKS LDSLRSGDLV LVWLQVKASN SVPDALVVDL LPAGLELENQ 
      1570       1580       1590       1600       1610       1620 
NLANGSASLE QSGGEVQNLL NQMQQASIKH IEFRDDRFVA AVAVDEYQPV TLVYLARAVT 
      1630       1640       1650    
PGTYQVPQPM VESMYVPQWR ATGAAEDLLI VRP

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P76578-18-unknown CDNNDN... 18 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LIVRP 1653 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)