TopFIND 4.0

P78329: Phylloquinone omega-hydroxylase CYP4F2 {ECO:0000305}

General Information

Protein names
- Phylloquinone omega-hydroxylase CYP4F2 {ECO:0000305}
- 1.14.14.78 {ECO:0000269|PubMed:24138531}
- 20-hydroxyeicosatetraenoic acid synthase {ECO:0000303|PubMed:10660572}
- 20-HETE synthase {ECO:0000303|PubMed:10660572}
- 1.14.14.- {ECO:0000269|PubMed:10660572}
- Arachidonic acid omega-hydroxylase {ECO:0000303|PubMed:10660572}
- CYPIVF2
- Cytochrome P450 4F2
- Cytochrome P450-LTB-omega
- Leukotriene-B(4) 20-monooxygenase 1
- Leukotriene-B(4) omega-hydroxylase 1 {ECO:0000305}
- 1.14.14.94 {ECO:0000269|PubMed:8026587, ECO:0000269|PubMed:9799565}
Gene names CYP4F2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P78329

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSQLSLSWLG LWPVAASPWL LLLLVGASWL LAHVLAWTYA FYDNCRRLRC FPQPPRRNWF 
        70         80         90        100        110        120 
WGHQGMVNPT EEGMRVLTQL VATYPQGFKV WMGPISPLLS LCHPDIIRSV INASAAIAPK 
       130        140        150        160        170        180 
DKFFYSFLEP WLGDGLLLSA GDKWSRHRRM LTPAFHFNIL KPYMKIFNES VNIMHAKWQL 
       190        200        210        220        230        240 
LASEGSACLD MFEHISLMTL DSLQKCVFSF DSHCQEKPSE YIAAILELSA LVSKRHHEIL 
       250        260        270        280        290        300 
LHIDFLYYLT PDGQRFRRAC RLVHDFTDAV IQERRRTLPS QGVDDFLQAK AKSKTLDFID 
       310        320        330        340        350        360 
VLLLSKDEDG KKLSDEDIRA EADTFMFEGH DTTASGLSWV LYHLAKHPEY QERCRQEVQE 
       370        380        390        400        410        420 
LLKDREPKEI EWDDLAHLPF LTMCMKESLR LHPPVPVISR HVTQDIVLPD GRVIPKGIIC 
       430        440        450        460        470        480 
LISVFGTHHN PAVWPDPEVY DPFRFDPENI KERSPLAFIP FSAGPRNCIG QTFAMAEMKV 
       490        500        510        520    
VLALTLLRFR VLPDHTEPRR KPELVLRAEG GLWLRVEPLS 

Isoforms

- Isoform 2 of Cytochrome P450 4F2

Sequence View

        10         20         30         40         50         60 
MSQLSLSWLG LWPVAASPWL LLLLVGASWL LAHVLAWTYA FYDNCRRLRC FPQPPRRNWF 
        70         80         90        100        110        120 
WGHQGMVNPT EEGMRVLTQL VATYPQGFKV WMGPISPLLS LCHPDIIRSV INASAAIAPK 
       130        140        150        160        170        180 
DKFFYSFLEP WLGDGLLLSA GDKWSRHRRM LTPAFHFNIL KPYMKIFNES VNIMHAKWQL 
       190        200        210        220        230        240 
LASEGSACLD MFEHISLMTL DSLQKCVFSF DSHCQEKPSE YIAAILELSA LVSKRHHEIL 
       250        260        270        280        290        300 
LHIDFLYYLT PDGQRFRRAC RLVHDFTDAV IQERRRTLPS QGVDDFLQAK AKSKTLDFID 
       310        320        330        340        350        360 
VLLLSKDEDG KKLSDEDIRA EADTFMFEGH DTTASGLSWV LYHLAKHPEY QERCRQEVQE 
       370        380        390        400        410        420 
LLKDREPKEI EWDDLAHLPF LTMCMKESLR LHPPVPVISR HVTQDIVLPD GRVIPKGIIC 
       430        440        450        460        470        480 
LISVFGTHHN PAVWPDPEVY DPFRFDPENI KERSPLAFIP FSAGPRNCIG QTFAMAEMKV 
       490        500        510        520    
VLALTLLRFR VLPDHTEPRR KPELVLRAEG GLWLRVEPLS 



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)