P78563: Double-stranded RNA-specific editase 1

General Information

Protein names	- Double-stranded RNA-specific editase 1 - 3.5.4.37 - RNA-editing deaminase 1 - RNA-editing enzyme 1 - dsRNA adenosine deaminase
Gene names	ADARB1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P78563

1 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDIEDEENMS SSSTDVKENR NLDNVSPKDG STPGPGEGSQ LSNGGGGGPG RKRPLEEGSN
        70         80         90        100        110        120
GHSKYRLKKR RKTPGPVLPK NALMQLNEIK PGLQYTLLSQ TGPVHAPLFV MSVEVNGQVF
       130        140        150        160        170        180
EGSGPTKKKA KLHAAEKALR SFVQFPNASE AHLAMGRTLS VNTDFTSDQA DFPDTLFNGF
       190        200        210        220        230        240
ETPDKAEPPF YVGSNGDDSF SSSGDLSLSA SPVPASLAQP PLPVLPPFPP PSGKNPVMIL
       250        260        270        280        290        300
NELRPGLKYD FLSESGESHA KSFVMSVVVD GQFFEGSGRN KKLAKARAAQ SALAAIFNLH
       310        320        330        340        350        360
LDQTPSRQPI PSEGLQLHLP QVLADAVSRL VLGKFGDLTD NFSSPHARRK VLAGVVMTTG
       370        380        390        400        410        420
TDVKDAKVIS VSTGTKCING EYMSDRGLAL NDCHAEIISR RSLLRFLYTQ LELYLNNKDD
       430        440        450        460        470        480
QKRSIFQKSE RGGFRLKENV QFHLYISTSP CGDARIFSPH EPILEGSRSY TQAGVQWCNH
       490        500        510        520        530        540
GSLQPRPPGL LSDPSTSTFQ GAGTTEPADR HPNRKARGQL RTKIESGEGT IPVRSNASIQ
       550        560        570        580        590        600
TWDGVLQGER LLTMSCSDKI ARWNVVGIQG SLLSIFVEPI YFSSIILGSL YHGDHLSRAM
       610        620        630        640        650        660
YQRISNIEDL PPLYTLNKPL LSGISNAEAR QPGKAPNFSV NWTVGDSAIE VINATTGKDE
       670        680        690        700        710        720
LGRASRLCKH ALYCRWMRVH GKVPSHLLRS KITKPNVYHE SKLAAKEYQA AKARLFTAFI
       730        740
KAGLGAWVEK PTEQDQFSLT P

Isoforms

- Isoform 2 of Double-stranded RNA-specific editase 1 - Isoform 3 of Double-stranded RNA-specific editase 1 - Isoform 4 of Double-stranded RNA-specific editase 1 - Isoform 5 of Double-stranded RNA-specific editase 1 - Isoform 5 of Double-stranded RNA-specific editase 1 - Isoform 6 of Double-stranded RNA-specific editase 1

Sequence View

        10         20         30         40         50         60
MDIEDEENMS SSSTDVKENR NLDNVSPKDG STPGPGEGSQ LSNGGGGGPG RKRPLEEGSN
        70         80         90        100        110        120
GHSKYRLKKR RKTPGPVLPK NALMQLNEIK PGLQYTLLSQ TGPVHAPLFV MSVEVNGQVF
       130        140        150        160        170        180
EGSGPTKKKA KLHAAEKALR SFVQFPNASE AHLAMGRTLS VNTDFTSDQA DFPDTLFNGF
       190        200        210        220        230        240
ETPDKAEPPF YVGSNGDDSF SSSGDLSLSA SPVPASLAQP PLPVLPPFPP PSGKNPVMIL
       250        260        270        280        290        300
NELRPGLKYD FLSESGESHA KSFVMSVVVD GQFFEGSGRN KKLAKARAAQ SALAAIFNLH
       310        320        330        340        350        360
LDQTPSRQPI PSEGLQLHLP QVLADAVSRL VLGKFGDLTD NFSSPHARRK VLAGVVMTTG
       370        380        390        400        410        420
TDVKDAKVIS VSTGTKCING EYMSDRGLAL NDCHAEIISR RSLLRFLYTQ LELYLNNKDD
       430        440        450        460        470        480
QKRSIFQKSE RGGFRLKENV QFHLYISTSP CGDARIFSPH EPILEGSRSY TQAGVQWCNH
       490        500        510        520        530        540
GSLQPRPPGL LSDPSTSTFQ GAGTTEPADR HPNRKARGQL RTKIESGEGT IPVRSNASIQ
       550        560        570        580        590        600
TWDGVLQGER LLTMSCSDKI ARWNVVGIQG SLLSIFVEPI YFSSIILGSL YHGDHLSRAM
       610        620        630        640        650        660
YQRISNIEDL PPLYTLNKPL LSGISNAEAR QPGKAPNFSV NWTVGDSAIE VINATTGKDE
       670        680        690        700        710        720
LGRASRLCKH ALYCRWMRVH GKVPSHLLRS KITKPNVYHE SKLAAKEYQA AKARLFTAFI
       730        740
KAGLGAWVEK PTEQDQFSLT P         10         20         30         40         50         60
MDIEDEENMS SSSTDVKENR NLDNVSPKDG STPGPGEGSQ LSNGGGGGPG RKRPLEEGSN
        70         80         90        100        110        120
GHSKYRLKKR RKTPGPVLPK NALMQLNEIK PGLQYTLLSQ TGPVHAPLFV MSVEVNGQVF
       130        140        150        160        170        180
EGSGPTKKKA KLHAAEKALR SFVQFPNASE AHLAMGRTLS VNTDFTSDQA DFPDTLFNGF
       190        200        210        220        230        240
ETPDKAEPPF YVGSNGDDSF SSSGDLSLSA SPVPASLAQP PLPVLPPFPP PSGKNPVMIL
       250        260        270        280        290        300
NELRPGLKYD FLSESGESHA KSFVMSVVVD GQFFEGSGRN KKLAKARAAQ SALAAIFNLH
       310        320        330        340        350        360
LDQTPSRQPI PSEGLQLHLP QVLADAVSRL VLGKFGDLTD NFSSPHARRK VLAGVVMTTG
       370        380        390        400        410        420
TDVKDAKVIS VSTGTKCING EYMSDRGLAL NDCHAEIISR RSLLRFLYTQ LELYLNNKDD
       430        440        450        460        470        480
QKRSIFQKSE RGGFRLKENV QFHLYISTSP CGDARIFSPH EPILEGSRSY TQAGVQWCNH
       490        500        510        520        530        540
GSLQPRPPGL LSDPSTSTFQ GAGTTEPADR HPNRKARGQL RTKIESGEGT IPVRSNASIQ
       550        560        570        580        590        600
TWDGVLQGER LLTMSCSDKI ARWNVVGIQG SLLSIFVEPI YFSSIILGSL YHGDHLSRAM
       610        620        630        640        650        660
YQRISNIEDL PPLYTLNKPL LSGISNAEAR QPGKAPNFSV NWTVGDSAIE VINATTGKDE
       670        680        690        700        710        720
LGRASRLCKH ALYCRWMRVH GKVPSHLLRS KITKPNVYHE SKLAAKEYQA AKARLFTAFI
       730        740
KAGLGAWVEK PTEQDQFSLT P         10         20         30         40         50         60
MDIEDEENMS SSSTDVKENR NLDNVSPKDG STPGPGEGSQ LSNGGGGGPG RKRPLEEGSN
        70         80         90        100        110        120
GHSKYRLKKR RKTPGPVLPK NALMQLNEIK PGLQYTLLSQ TGPVHAPLFV MSVEVNGQVF
       130        140        150        160        170        180
EGSGPTKKKA KLHAAEKALR SFVQFPNASE AHLAMGRTLS VNTDFTSDQA DFPDTLFNGF
       190        200        210        220        230        240
ETPDKAEPPF YVGSNGDDSF SSSGDLSLSA SPVPASLAQP PLPVLPPFPP PSGKNPVMIL
       250        260        270        280        290        300
NELRPGLKYD FLSESGESHA KSFVMSVVVD GQFFEGSGRN KKLAKARAAQ SALAAIFNLH
       310        320        330        340        350        360
LDQTPSRQPI PSEGLQLHLP QVLADAVSRL VLGKFGDLTD NFSSPHARRK VLAGVVMTTG
       370        380        390        400        410        420
TDVKDAKVIS VSTGTKCING EYMSDRGLAL NDCHAEIISR RSLLRFLYTQ LELYLNNKDD
       430        440        450        460        470        480
QKRSIFQKSE RGGFRLKENV QFHLYISTSP CGDARIFSPH EPILEGSRSY TQAGVQWCNH
       490        500        510        520        530        540
GSLQPRPPGL LSDPSTSTFQ GAGTTEPADR HPNRKARGQL RTKIESGEGT IPVRSNASIQ
       550        560        570        580        590        600
TWDGVLQGER LLTMSCSDKI ARWNVVGIQG SLLSIFVEPI YFSSIILGSL YHGDHLSRAM
       610        620        630        640        650        660
YQRISNIEDL PPLYTLNKPL LSGISNAEAR QPGKAPNFSV NWTVGDSAIE VINATTGKDE
       670        680        690        700        710        720
LGRASRLCKH ALYCRWMRVH GKVPSHLLRS KITKPNVYHE SKLAAKEYQA AKARLFTAFI
       730        740
KAGLGAWVEK PTEQDQFSLT P         10         20         30         40         50         60
MDIEDEENMS SSSTDVKENR NLDNVSPKDG STPGPGEGSQ LSNGGGGGPG RKRPLEEGSN
        70         80         90        100        110        120
GHSKYRLKKR RKTPGPVLPK NALMQLNEIK PGLQYTLLSQ TGPVHAPLFV MSVEVNGQVF
       130        140        150        160        170        180
EGSGPTKKKA KLHAAEKALR SFVQFPNASE AHLAMGRTLS VNTDFTSDQA DFPDTLFNGF
       190        200        210        220        230        240
ETPDKAEPPF YVGSNGDDSF SSSGDLSLSA SPVPASLAQP PLPVLPPFPP PSGKNPVMIL
       250        260        270        280        290        300
NELRPGLKYD FLSESGESHA KSFVMSVVVD GQFFEGSGRN KKLAKARAAQ SALAAIFNLH
       310        320        330        340        350        360
LDQTPSRQPI PSEGLQLHLP QVLADAVSRL VLGKFGDLTD NFSSPHARRK VLAGVVMTTG
       370        380        390        400        410        420
TDVKDAKVIS VSTGTKCING EYMSDRGLAL NDCHAEIISR RSLLRFLYTQ LELYLNNKDD
       430        440        450        460        470        480
QKRSIFQKSE RGGFRLKENV QFHLYISTSP CGDARIFSPH EPILEGSRSY TQAGVQWCNH
       490        500        510        520        530        540
GSLQPRPPGL LSDPSTSTFQ GAGTTEPADR HPNRKARGQL RTKIESGEGT IPVRSNASIQ
       550        560        570        580        590        600
TWDGVLQGER LLTMSCSDKI ARWNVVGIQG SLLSIFVEPI YFSSIILGSL YHGDHLSRAM
       610        620        630        640        650        660
YQRISNIEDL PPLYTLNKPL LSGISNAEAR QPGKAPNFSV NWTVGDSAIE VINATTGKDE
       670        680        690        700        710        720
LGRASRLCKH ALYCRWMRVH GKVPSHLLRS KITKPNVYHE SKLAAKEYQA AKARLFTAFI
       730        740
KAGLGAWVEK PTEQDQFSLT P         10         20         30         40         50         60
MDIEDEENMS SSSTDVKENR NLDNVSPKDG STPGPGEGSQ LSNGGGGGPG RKRPLEEGSN
        70         80         90        100        110        120
GHSKYRLKKR RKTPGPVLPK NALMQLNEIK PGLQYTLLSQ TGPVHAPLFV MSVEVNGQVF
       130        140        150        160        170        180
EGSGPTKKKA KLHAAEKALR SFVQFPNASE AHLAMGRTLS VNTDFTSDQA DFPDTLFNGF
       190        200        210        220        230        240
ETPDKAEPPF YVGSNGDDSF SSSGDLSLSA SPVPASLAQP PLPVLPPFPP PSGKNPVMIL
       250        260        270        280        290        300
NELRPGLKYD FLSESGESHA KSFVMSVVVD GQFFEGSGRN KKLAKARAAQ SALAAIFNLH
       310        320        330        340        350        360
LDQTPSRQPI PSEGLQLHLP QVLADAVSRL VLGKFGDLTD NFSSPHARRK VLAGVVMTTG
       370        380        390        400        410        420
TDVKDAKVIS VSTGTKCING EYMSDRGLAL NDCHAEIISR RSLLRFLYTQ LELYLNNKDD
       430        440        450        460        470        480
QKRSIFQKSE RGGFRLKENV QFHLYISTSP CGDARIFSPH EPILEGSRSY TQAGVQWCNH
       490        500        510        520        530        540
GSLQPRPPGL LSDPSTSTFQ GAGTTEPADR HPNRKARGQL RTKIESGEGT IPVRSNASIQ
       550        560        570        580        590        600
TWDGVLQGER LLTMSCSDKI ARWNVVGIQG SLLSIFVEPI YFSSIILGSL YHGDHLSRAM
       610        620        630        640        650        660
YQRISNIEDL PPLYTLNKPL LSGISNAEAR QPGKAPNFSV NWTVGDSAIE VINATTGKDE
       670        680        690        700        710        720
LGRASRLCKH ALYCRWMRVH GKVPSHLLRS KITKPNVYHE SKLAAKEYQA AKARLFTAFI
       730        740
KAGLGAWVEK PTEQDQFSLT P         10         20         30         40         50         60
MDIEDEENMS SSSTDVKENR NLDNVSPKDG STPGPGEGSQ LSNGGGGGPG RKRPLEEGSN
        70         80         90        100        110        120
GHSKYRLKKR RKTPGPVLPK NALMQLNEIK PGLQYTLLSQ TGPVHAPLFV MSVEVNGQVF
       130        140        150        160        170        180
EGSGPTKKKA KLHAAEKALR SFVQFPNASE AHLAMGRTLS VNTDFTSDQA DFPDTLFNGF
       190        200        210        220        230        240
ETPDKAEPPF YVGSNGDDSF SSSGDLSLSA SPVPASLAQP PLPVLPPFPP PSGKNPVMIL
       250        260        270        280        290        300
NELRPGLKYD FLSESGESHA KSFVMSVVVD GQFFEGSGRN KKLAKARAAQ SALAAIFNLH
       310        320        330        340        350        360
LDQTPSRQPI PSEGLQLHLP QVLADAVSRL VLGKFGDLTD NFSSPHARRK VLAGVVMTTG
       370        380        390        400        410        420
TDVKDAKVIS VSTGTKCING EYMSDRGLAL NDCHAEIISR RSLLRFLYTQ LELYLNNKDD
       430        440        450        460        470        480
QKRSIFQKSE RGGFRLKENV QFHLYISTSP CGDARIFSPH EPILEGSRSY TQAGVQWCNH
       490        500        510        520        530        540
GSLQPRPPGL LSDPSTSTFQ GAGTTEPADR HPNRKARGQL RTKIESGEGT IPVRSNASIQ
       550        560        570        580        590        600
TWDGVLQGER LLTMSCSDKI ARWNVVGIQG SLLSIFVEPI YFSSIILGSL YHGDHLSRAM
       610        620        630        640        650        660
YQRISNIEDL PPLYTLNKPL LSGISNAEAR QPGKAPNFSV NWTVGDSAIE VINATTGKDE
       670        680        690        700        710        720
LGRASRLCKH ALYCRWMRVH GKVPSHLLRS KITKPNVYHE SKLAAKEYQA AKARLFTAFI
       730        740
KAGLGAWVEK PTEQDQFSLT P

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P78563-1-unknown	MDIEDE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P78563-1-unknown	MDIEDE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87247
P78563-1-unknown	MDIEDE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87248
P78563-1-unknown	MDIEDE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104377
P78563-1-unknown	MDIEDE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104376

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KALRSF	141	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000387480
...KALRSF	141	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154878
...KALRSF	141	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154879
...KALRSF	141	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154877
...KALRSF	141	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154876
...FSLTP	741	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FSLTP	741	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82865
...FSLTP	741	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82867
...FSLTP	741	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82868

TopFIND

P78563: Double-stranded RNA-specific editase 1

General Information

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates