TopFIND 4.0

P80188: Neutrophil gelatinase-associated lipocalin {ECO:0000303|PubMed:9339356}

General Information

Protein names
- Neutrophil gelatinase-associated lipocalin {ECO:0000303|PubMed:9339356}
- NGAL
- 25 kDa alpha-2-microglobulin-related subunit of MMP-9 {ECO:0000303|PubMed:1281792}
- Lipocalin-2
- Oncogene 24p3
- Siderocalin {ECO:0000303|PubMed:15642259, ECO:0000303|PubMed:20581821}
- p25
Gene names LCN2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P80188

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPLGLLWLGL ALLGALHAQA QDSTSDLIPA PPLSKVPLQQ NFQDNQFQGK WYVVGLAGNA 
        70         80         90        100        110        120 
ILREDKDPQK MYATIYELKE DKSYNVTSVL FRKKKCDYWI RTFVPGCQPG EFTLGNIKSY 
       130        140        150        160        170        180 
PGLTSYLVRV VSTNYNQHAM VFFKKVSQNR EYFKITLYGR TKELTSELKE NFIRFSKSLG 
       190    
LPENHIVFPV PIDQCIDG

Isoforms

- Isoform 2 of Neutrophil gelatinase-associated lipocalin

Sequence View

        10         20         30         40         50         60 
MPLGLLWLGL ALLGALHAQA QDSTSDLIPA PPLSKVPLQQ NFQDNQFQGK WYVVGLAGNA 
        70         80         90        100        110        120 
ILREDKDPQK MYATIYELKE DKSYNVTSVL FRKKKCDYWI RTFVPGCQPG EFTLGNIKSY 
       130        140        150        160        170        180 
PGLTSYLVRV VSTNYNQHAM VFFKKVSQNR EYFKITLYGR TKELTSELKE NFIRFSKSLG 
       190    
LPENHIVFPV PIDQCIDG



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P80188-1-unknown MPLGLL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt82812
    P80188-21-Pyrrolidone carboxylic acid QDSTSD... 21 pyrrolidone carboxylic acid- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P80188-21-Pyrrolidone carboxylic acid QDSTSD... 21 pyrrolidone carboxylic acid- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112556

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QCIDG 198 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)