P85298: Rho GTPase-activating protein 8

General Information

Protein names	- Rho GTPase-activating protein 8 - Rho-type GTPase-activating protein 8
Gene names	ARHGAP8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P85298

1 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Rho GTPase-activating protein 8 - Isoform 3 of Rho GTPase-activating protein 8 - Isoform 4 of Rho GTPase-activating protein 8 - Isoform 5 of Rho GTPase-activating protein 8

Sequence View

        10         20         30         40         50         60
MAGQDPALST SHPFYDVARH GILQVAGDDR FGRRVVTFSC CRMPPSHELD HQRLLEYLKY
        70         80         90        100        110        120
TLDQYVENDY TIVYFHYGLN SRNKPSLGWL QSAYKEFDRK DGDLTMWPRL VSNSKLKRSS
       130        140        150        160        170        180
HLSLPKYWDY RYKKNLKALY VVHPTSFIKV LWNILKPLIS HKFGKKVIYF NYLSELHEHL
       190        200        210        220        230        240
KYDQLVIPPE VLRYDEKLQS LHEGRTPPPT KTPPPRPPLP TQQFGVSLQY LKDKNQGELI
       250        260        270        280        290        300
PPVLRFTVTY LREKGLRTEG LFRRSASVQT VREIQRLYNQ GKPVNFDDYG DIHIPAVILK
       310        320        330        340        350        360
TFLRELPQPL LTFQAYEQIL GITCVESSLR VTGCRQILRS LPEHNYVVLR YLMGFLHAVS
       370        380        390        400        410        420
RESIFNKMNS SNLACVFGLN LIWPSQGVSS LSALVPLNMF TELLIEYYEK IFSTPEAPGE
       430        440        450        460
HGLAPWEQGS RAAPLQEAVP RTQATGLTKP TLPPSPLMAA RRRL         10         20         30         40         50         60
MAGQDPALST SHPFYDVARH GILQVAGDDR FGRRVVTFSC CRMPPSHELD HQRLLEYLKY
        70         80         90        100        110        120
TLDQYVENDY TIVYFHYGLN SRNKPSLGWL QSAYKEFDRK DGDLTMWPRL VSNSKLKRSS
       130        140        150        160        170        180
HLSLPKYWDY RYKKNLKALY VVHPTSFIKV LWNILKPLIS HKFGKKVIYF NYLSELHEHL
       190        200        210        220        230        240
KYDQLVIPPE VLRYDEKLQS LHEGRTPPPT KTPPPRPPLP TQQFGVSLQY LKDKNQGELI
       250        260        270        280        290        300
PPVLRFTVTY LREKGLRTEG LFRRSASVQT VREIQRLYNQ GKPVNFDDYG DIHIPAVILK
       310        320        330        340        350        360
TFLRELPQPL LTFQAYEQIL GITCVESSLR VTGCRQILRS LPEHNYVVLR YLMGFLHAVS
       370        380        390        400        410        420
RESIFNKMNS SNLACVFGLN LIWPSQGVSS LSALVPLNMF TELLIEYYEK IFSTPEAPGE
       430        440        450        460
HGLAPWEQGS RAAPLQEAVP RTQATGLTKP TLPPSPLMAA RRRL         10         20         30         40         50         60
MAGQDPALST SHPFYDVARH GILQVAGDDR FGRRVVTFSC CRMPPSHELD HQRLLEYLKY
        70         80         90        100        110        120
TLDQYVENDY TIVYFHYGLN SRNKPSLGWL QSAYKEFDRK DGDLTMWPRL VSNSKLKRSS
       130        140        150        160        170        180
HLSLPKYWDY RYKKNLKALY VVHPTSFIKV LWNILKPLIS HKFGKKVIYF NYLSELHEHL
       190        200        210        220        230        240
KYDQLVIPPE VLRYDEKLQS LHEGRTPPPT KTPPPRPPLP TQQFGVSLQY LKDKNQGELI
       250        260        270        280        290        300
PPVLRFTVTY LREKGLRTEG LFRRSASVQT VREIQRLYNQ GKPVNFDDYG DIHIPAVILK
       310        320        330        340        350        360
TFLRELPQPL LTFQAYEQIL GITCVESSLR VTGCRQILRS LPEHNYVVLR YLMGFLHAVS
       370        380        390        400        410        420
RESIFNKMNS SNLACVFGLN LIWPSQGVSS LSALVPLNMF TELLIEYYEK IFSTPEAPGE
       430        440        450        460
HGLAPWEQGS RAAPLQEAVP RTQATGLTKP TLPPSPLMAA RRRL         10         20         30         40         50         60
MAGQDPALST SHPFYDVARH GILQVAGDDR FGRRVVTFSC CRMPPSHELD HQRLLEYLKY
        70         80         90        100        110        120
TLDQYVENDY TIVYFHYGLN SRNKPSLGWL QSAYKEFDRK DGDLTMWPRL VSNSKLKRSS
       130        140        150        160        170        180
HLSLPKYWDY RYKKNLKALY VVHPTSFIKV LWNILKPLIS HKFGKKVIYF NYLSELHEHL
       190        200        210        220        230        240
KYDQLVIPPE VLRYDEKLQS LHEGRTPPPT KTPPPRPPLP TQQFGVSLQY LKDKNQGELI
       250        260        270        280        290        300
PPVLRFTVTY LREKGLRTEG LFRRSASVQT VREIQRLYNQ GKPVNFDDYG DIHIPAVILK
       310        320        330        340        350        360
TFLRELPQPL LTFQAYEQIL GITCVESSLR VTGCRQILRS LPEHNYVVLR YLMGFLHAVS
       370        380        390        400        410        420
RESIFNKMNS SNLACVFGLN LIWPSQGVSS LSALVPLNMF TELLIEYYEK IFSTPEAPGE
       430        440        450        460
HGLAPWEQGS RAAPLQEAVP RTQATGLTKP TLPPSPLMAA RRRL

Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P85298-1-unknown	MAGQDP...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P85298-1-unknown	MAGQDP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87599
P85298-1-unknown	MAGQDP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87600
P85298-1-unknown	MAGQDP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87601
P85298-1-unknown	MAGQDP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87602

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KYWDYR	130	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000379425
...ARRRL	464	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ARRRL	464	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83219
...ARRRL	464	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83218

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

P85298: Rho GTPase-activating protein 8

General Information

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates