TopFIND 4.0

P97411: Islet cell autoantigen 1

General Information

Protein names
- Islet cell autoantigen 1
- 69 kDa islet cell autoantigen
- ICA69
- Islet cell autoantigen p69
- ICAp69
- p69
Gene names Ica1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P97411

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSGHKCYSWE LQDRFAQDKS VVNKMQQKYW ETKQAFIKAT GKKEDEHVVA SDADLDAKLE 
        70         80         90        100        110        120 
LFHSIQRTCL DLSKAIVLYQ KRICFLSQEE NELGKFLRSQ GFQDKTRAGK MMQATGKALC 
       130        140        150        160        170        180 
FSSQQRLALR NPLCRFHQEV ETFRHRAISD TWLTVNRMEQ YRTEYRGALL WMKDVSQELD 
       190        200        210        220        230        240 
PDLYKQMEKF RKVQTQVRLA KKNFDKLKMD VCQKVDLLGA SRCNLLSHML ATYQTTLLHF 
       250        260        270        280        290        300 
WEKTSHTMAA IHESFKGYQP YEFTTLKSLQ DPMKKLVEKE GKKTSWRENR EAVAPEPRQL 
       310        320        330        340        350        360 
ISLEDEHKDS SAYKTEEGTS VLSSVDKGSV HDTCSGPIDE LLDGKPEEAC LGPTAGTPEP 
       370        380        390        400        410        420 
ESGDKDDLLL LNEIFSTSCL DEGEFSREWA AVFGDDQLKE PAPMGAQGEP DPKPQIGSGF 
       430        440        450        460        470    
LPSQLLDQNM KDLQASLQEP AKAASDLTAW FSLFADLDPL SNPDAVGKTD KEHELLNA

Isoforms

- Isoform 2 of Islet cell autoantigen 1

Sequence View

        10         20         30         40         50         60 
MSGHKCYSWE LQDRFAQDKS VVNKMQQKYW ETKQAFIKAT GKKEDEHVVA SDADLDAKLE 
        70         80         90        100        110        120 
LFHSIQRTCL DLSKAIVLYQ KRICFLSQEE NELGKFLRSQ GFQDKTRAGK MMQATGKALC 
       130        140        150        160        170        180 
FSSQQRLALR NPLCRFHQEV ETFRHRAISD TWLTVNRMEQ YRTEYRGALL WMKDVSQELD 
       190        200        210        220        230        240 
PDLYKQMEKF RKVQTQVRLA KKNFDKLKMD VCQKVDLLGA SRCNLLSHML ATYQTTLLHF 
       250        260        270        280        290        300 
WEKTSHTMAA IHESFKGYQP YEFTTLKSLQ DPMKKLVEKE GKKTSWRENR EAVAPEPRQL 
       310        320        330        340        350        360 
ISLEDEHKDS SAYKTEEGTS VLSSVDKGSV HDTCSGPIDE LLDGKPEEAC LGPTAGTPEP 
       370        380        390        400        410        420 
ESGDKDDLLL LNEIFSTSCL DEGEFSREWA AVFGDDQLKE PAPMGAQGEP DPKPQIGSGF 
       430        440        450        460        470    
LPSQLLDQNM KDLQASLQEP AKAASDLTAW FSLFADLDPL SNPDAVGKTD KEHELLNA



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P97411-1-unknown MSGHKC... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P97411-1-unknown MSGHKC... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77467

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ELLNA 478 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ELLNA 478 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73085

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)