TopFIND 4.0

P97785: GDNF family receptor alpha-1

General Information

Protein names
- GDNF family receptor alpha-1
- GDNF receptor alpha-1
- GDNFR-alpha-1
- GFR-alpha-1
- TGF-beta-related neurotrophic factor receptor 1
Gene names Gfra1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P97785

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFLATLYFVL PLLDLLMSAE VSGGDRLDCV KASDQCLKEQ SCSTKYRTLR QCVAGKETNF 
        70         80         90        100        110        120 
SLTSGLEAKD ECRSAMEALK QKSLYNCRCK RGMKKEKNCL RIYWSMYQSL QGNDLLEDSP 
       130        140        150        160        170        180 
YEPVNSRLSD IFRAVPFISD VFQQVEHISK GNNCLDAAKA CNLDDTCKKY RSAYITPCTT 
       190        200        210        220        230        240 
SMSNEVCNRR KCHKALRQFF DKVPAKHSYG MLFCSCRDVA CTERRRQTIV PVCSYEERER 
       250        260        270        280        290        300 
PNCLNLQDSC KTNYICRSRL ADFFTNCQPE SRSVSNCLKE NYADCLLAYS GLIGTVMTPN 
       310        320        330        340        350        360 
YIDSSSLSVA PWCDCSNSGN DLEDCLKFLN FFKDNTCLKN AIQAFGNGSD VTMWQPAPPV 
       370        380        390        400        410        420 
QTTTATTTTA FRIKNKPLGP AGSENEIPTH VLPPCANLQA QKLKSNVSGS THLCLSDNDY 
       430        440        450        460    
GKDGLAGASS HITTKSMAAP PSCGLSSLPV MVFTALAALL SVSLAETS

Isoforms

- Isoform 2 of GDNF family receptor alpha-1

Sequence View

        10         20         30         40         50         60 
MFLATLYFVL PLLDLLMSAE VSGGDRLDCV KASDQCLKEQ SCSTKYRTLR QCVAGKETNF 
        70         80         90        100        110        120 
SLTSGLEAKD ECRSAMEALK QKSLYNCRCK RGMKKEKNCL RIYWSMYQSL QGNDLLEDSP 
       130        140        150        160        170        180 
YEPVNSRLSD IFRAVPFISD VFQQVEHISK GNNCLDAAKA CNLDDTCKKY RSAYITPCTT 
       190        200        210        220        230        240 
SMSNEVCNRR KCHKALRQFF DKVPAKHSYG MLFCSCRDVA CTERRRQTIV PVCSYEERER 
       250        260        270        280        290        300 
PNCLNLQDSC KTNYICRSRL ADFFTNCQPE SRSVSNCLKE NYADCLLAYS GLIGTVMTPN 
       310        320        330        340        350        360 
YIDSSSLSVA PWCDCSNSGN DLEDCLKFLN FFKDNTCLKN AIQAFGNGSD VTMWQPAPPV 
       370        380        390        400        410        420 
QTTTATTTTA FRIKNKPLGP AGSENEIPTH VLPPCANLQA QKLKSNVSGS THLCLSDNDY 
       430        440        450        460    
GKDGLAGASS HITTKSMAAP PSCGLSSLPV MVFTALAALL SVSLAETS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P97785-1-unknown MFLATL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75901
    P97785-25-unknown DRLDCV... 25 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P97785-25-unknown DRLDCV... 25 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113852

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)