TopFIND 4.0

P97793: ALK tyrosine kinase receptor

General Information

Protein names
- ALK tyrosine kinase receptor
- 2.7.10.1
- Anaplastic lymphoma kinase
- CD246
Gene names Alk
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P97793

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGAAGFLWLL PPLLLAAASY SGAATDQRAG SPASGPPLQP REPLSYSRLQ RKSLAVDFVV 
        70         80         90        100        110        120 
PSLFRVYARD LLLPQPRSPS EPEAGGLEAR GSLALDCEPL LRLLGPLPGI SWADGASSPS 
       130        140        150        160        170        180 
PEAGPTLSRV LKGGSVRKLR RAKQLVLELG EETILEGCIG PPEEVAAVGI LQFNLSELFS 
       190        200        210        220        230        240 
WWILHGEGRL RIRLMPEKKA SEVGREGRLS SAIRASQPRL LFQIFGTGHS SMESPSETPS 
       250        260        270        280        290        300 
PPGTFMWNLT WTMKDSFPFL SHRSRYGLEC SFDFPCELEY SPPLHNHGNQ SWSWRHVPSE 
       310        320        330        340        350        360 
EASRMNLLDG PEAEHSQEMP RGSFLLLNTS ADSKHTILSP WMRSSSDHCT LAVSVHRHLQ 
       370        380        390        400        410        420 
PSGRYVAQLL PHNEAGREIL LVPTPGKHGW TVLQGRVGRP ANPFRVALEY ISSGNRSLSA 
       430        440        450        460        470        480 
VDFFALKNCS EGTSPGSKMA LQSSFTCWNG TVLQLGQACD FHQDCAQGED EGQLCSKLPA 
       490        500        510        520        530        540 
GFYCNFENGF CGWTQSPLSP HMPRWQVRTL RDAHSQGHQG RALLLSTTDI LASEGATVTS 
       550        560        570        580        590        600 
ATFPAPMKNS PCELRMSWLI RGVLRGNVSL VLVENKTGKE QSRTVWHVAT DEGLSLWQHT 
       610        620        630        640        650        660 
VLSLLDVTDR FWLQIVTWWG PGSRATVGFD NISISLDCYL TISGEEKMSL NSVPKSRNLF 
       670        680        690        700        710        720 
EKNPNKESKS WANISGPTPI FDPTVHWLFT TCGASGPHGP TQAQCNNAYQ NSNLSVVVGS 
       730        740        750        760        770        780 
EGPLKGVQIW KVPATDTYSI SGYGAAGGKG GKNTMMRSHG VSVLGIFNLE KGDTLYILVG 
       790        800        810        820        830        840 
QQGEDACPRA NQLIQKVCVG ENNVIEEEIR VNRSVHEWAG GGGGGGGATY VFKMKDGVPV 
       850        860        870        880        890        900 
PLIIAAGGGG RAYGAKTETF HPERLESNSS VLGLNGNSGA AGGGGGWNDN TSLLWAGKSL 
       910        920        930        940        950        960 
LEGAAGGHSC PQAMKKWGWE TRGGFGGGGG GCSSGGGGGG YIGGNAASNN DPEMDGEDGV 
       970        980        990       1000       1010       1020 
SFISPLGILY TPALKVMEGH GEVNIKHYLN CSHCEVDECH MDPESHKVIC FCDHGTVLAD 
      1030       1040       1050       1060       1070       1080 
DGVSCIVSPT PEPHLPLSLI LSVVTSALVA ALVLAFSGIM IVYRRKHQEL QAMQMELQSP 
      1090       1100       1110       1120       1130       1140 
EYKLSKLRTS TIMTDYNPNY CFAGKTSSIS DLKEVPRKNI TLIRGLGHGA FGEVYEGQVS 
      1150       1160       1170       1180       1190       1200 
GMPNDPSPLQ VAVKTLPEVC SEQDELDFLM EALIISKFNH QNIVRCIGVS LQALPRFILL 
      1210       1220       1230       1240       1250       1260 
ELMAGGDLKS FLRETRPRPN QPTSLAMLDL LHVARDIACG CQYLEENHFI HRDIAARNCL 
      1270       1280       1290       1300       1310       1320 
LTCPGAGRIA KIGDFGMARD IYRASYYRKG GCAMLPVKWM PPEAFMEGIF TSKTDTWSFG 
      1330       1340       1350       1360       1370       1380 
VLLWEIFSLG YMPYPSKSNQ EVLEFVTSGG RMDPPKNCPG PVYRIMTQCW QHQPEDRPNF 
      1390       1400       1410       1420       1430       1440 
AIILERIEYC TQDPDVINTA LPIEYGPVVE EEEKVPMRPK DPEGMPPLLV SPQPAKHEEA 
      1450       1460       1470       1480       1490       1500 
SAAPQPAALT APGPSVKKPP GAGAGAGAGA GAGPVPRGAA DRGHVNMAFS QPNPPPELHK 
      1510       1520       1530       1540       1550       1560 
GPGSRNKPTS LWNPTYGSWF TEKPAKKTHP PPGAEPQARA GAAEGGWTGP GAGPRRAEAA 
      1570       1580       1590       1600       1610       1620 
LLLEPSALSA TMKEVPLFRL RHFPCGNVNY GYQQQGLPLE ATAAPGDTML KSKNKVTQPG 
   
P

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P97793-19-unknown SYSGAA... 19 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TQPGP 1621 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)