P97797: Tyrosine-protein phosphatase non-receptor type substrate 1

General Information

Protein names	- Tyrosine-protein phosphatase non-receptor type substrate 1 - SHP substrate 1 - SHPS-1 - Brain Ig-like molecule with tyrosine-based activation motifs - Bit - CD172 antigen-like family member A - Inhibitory receptor SHPS-1 - MyD-1 antigen - Signal-regulatory protein alpha-1 - Sirp-alpha-1 - mSIRP-alpha1 - p84 - CD172a
Gene names	Sirpa
Organism	Mus musculus
Protease Family
Protease ID	I43.001
Chromosome location
UniProt ID	P97797

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEPAGPAPGR LGPLLLCLLL SASCFCTGAT GKELKVTQPE KSVSVAAGDS TVLNCTLTSL
        70         80         90        100        110        120
LPVGPIRWYR GVGPSRLLIY SFAGEYVPRI RNVSDTTKRN NMDFSIRISN VTPADAGIYY
       130        140        150        160        170        180
CVKFQKGSSE PDTEIQSGGG TEVYVLAKPS PPEVSGPADR GIPDQKVNFT CKSHGFSPRN
       190        200        210        220        230        240
ITLKWFKDGQ ELHPLETTVN PSGKNVSYNI SSTVRVVLNS MDVNSKVICE VAHITLDRSP
       250        260        270        280        290        300
LRGIANLSNF IRVSPTVKVT QQSPTSMNQV NLTCRAERFY PEDLQLIWLE NGNVSRNDTP
       310        320        330        340        350        360
KNLTKNTDGT YNYTSLFLVN SSAHREDVVF TCQVKHDQQP AITRNHTVLG FAHSSDQGSM
       370        380        390        400        410        420
QTFPDNNATH NWNVFIGVGV ACALLVVLLM AALYLLRIKQ KKAKGSTSST RLHEPEKNAR
       430        440        450        460        470        480
EITQVQSLIQ DTNDINDITY ADLNLPKEKK PAPRAPEPNN HTEYASIETG KVPRPEDTLT
       490        500        510
YADLDMVHLS RAQPAPKPEP SFSEYASVQV QRK

Isoforms

- Isoform 2 of Tyrosine-protein phosphatase non-receptor type substrate 1 - Isoform 3 of Tyrosine-protein phosphatase non-receptor type substrate 1 - Isoform 2 of Tyrosine-protein phosphatase non-receptor type substrate 1 - Isoform 3 of Tyrosine-protein phosphatase non-receptor type substrate 1 - Isoform 4 of Tyrosine-protein phosphatase non-receptor type substrate 1

Sequence View

        10         20         30         40         50         60
MEPAGPAPGR LGPLLLCLLL SASCFCTGAT GKELKVTQPE KSVSVAAGDS TVLNCTLTSL
        70         80         90        100        110        120
LPVGPIRWYR GVGPSRLLIY SFAGEYVPRI RNVSDTTKRN NMDFSIRISN VTPADAGIYY
       130        140        150        160        170        180
CVKFQKGSSE PDTEIQSGGG TEVYVLAKPS PPEVSGPADR GIPDQKVNFT CKSHGFSPRN
       190        200        210        220        230        240
ITLKWFKDGQ ELHPLETTVN PSGKNVSYNI SSTVRVVLNS MDVNSKVICE VAHITLDRSP
       250        260        270        280        290        300
LRGIANLSNF IRVSPTVKVT QQSPTSMNQV NLTCRAERFY PEDLQLIWLE NGNVSRNDTP
       310        320        330        340        350        360
KNLTKNTDGT YNYTSLFLVN SSAHREDVVF TCQVKHDQQP AITRNHTVLG FAHSSDQGSM
       370        380        390        400        410        420
QTFPDNNATH NWNVFIGVGV ACALLVVLLM AALYLLRIKQ KKAKGSTSST RLHEPEKNAR
       430        440        450        460        470        480
EITQVQSLIQ DTNDINDITY ADLNLPKEKK PAPRAPEPNN HTEYASIETG KVPRPEDTLT
       490        500        510
YADLDMVHLS RAQPAPKPEP SFSEYASVQV QRK         10         20         30         40         50         60
MEPAGPAPGR LGPLLLCLLL SASCFCTGAT GKELKVTQPE KSVSVAAGDS TVLNCTLTSL
        70         80         90        100        110        120
LPVGPIRWYR GVGPSRLLIY SFAGEYVPRI RNVSDTTKRN NMDFSIRISN VTPADAGIYY
       130        140        150        160        170        180
CVKFQKGSSE PDTEIQSGGG TEVYVLAKPS PPEVSGPADR GIPDQKVNFT CKSHGFSPRN
       190        200        210        220        230        240
ITLKWFKDGQ ELHPLETTVN PSGKNVSYNI SSTVRVVLNS MDVNSKVICE VAHITLDRSP
       250        260        270        280        290        300
LRGIANLSNF IRVSPTVKVT QQSPTSMNQV NLTCRAERFY PEDLQLIWLE NGNVSRNDTP
       310        320        330        340        350        360
KNLTKNTDGT YNYTSLFLVN SSAHREDVVF TCQVKHDQQP AITRNHTVLG FAHSSDQGSM
       370        380        390        400        410        420
QTFPDNNATH NWNVFIGVGV ACALLVVLLM AALYLLRIKQ KKAKGSTSST RLHEPEKNAR
       430        440        450        460        470        480
EITQVQSLIQ DTNDINDITY ADLNLPKEKK PAPRAPEPNN HTEYASIETG KVPRPEDTLT
       490        500        510
YADLDMVHLS RAQPAPKPEP SFSEYASVQV QRK         10         20         30         40         50         60
MEPAGPAPGR LGPLLLCLLL SASCFCTGAT GKELKVTQPE KSVSVAAGDS TVLNCTLTSL
        70         80         90        100        110        120
LPVGPIRWYR GVGPSRLLIY SFAGEYVPRI RNVSDTTKRN NMDFSIRISN VTPADAGIYY
       130        140        150        160        170        180
CVKFQKGSSE PDTEIQSGGG TEVYVLAKPS PPEVSGPADR GIPDQKVNFT CKSHGFSPRN
       190        200        210        220        230        240
ITLKWFKDGQ ELHPLETTVN PSGKNVSYNI SSTVRVVLNS MDVNSKVICE VAHITLDRSP
       250        260        270        280        290        300
LRGIANLSNF IRVSPTVKVT QQSPTSMNQV NLTCRAERFY PEDLQLIWLE NGNVSRNDTP
       310        320        330        340        350        360
KNLTKNTDGT YNYTSLFLVN SSAHREDVVF TCQVKHDQQP AITRNHTVLG FAHSSDQGSM
       370        380        390        400        410        420
QTFPDNNATH NWNVFIGVGV ACALLVVLLM AALYLLRIKQ KKAKGSTSST RLHEPEKNAR
       430        440        450        460        470        480
EITQVQSLIQ DTNDINDITY ADLNLPKEKK PAPRAPEPNN HTEYASIETG KVPRPEDTLT
       490        500        510
YADLDMVHLS RAQPAPKPEP SFSEYASVQV QRK         10         20         30         40         50         60
MEPAGPAPGR LGPLLLCLLL SASCFCTGAT GKELKVTQPE KSVSVAAGDS TVLNCTLTSL
        70         80         90        100        110        120
LPVGPIRWYR GVGPSRLLIY SFAGEYVPRI RNVSDTTKRN NMDFSIRISN VTPADAGIYY
       130        140        150        160        170        180
CVKFQKGSSE PDTEIQSGGG TEVYVLAKPS PPEVSGPADR GIPDQKVNFT CKSHGFSPRN
       190        200        210        220        230        240
ITLKWFKDGQ ELHPLETTVN PSGKNVSYNI SSTVRVVLNS MDVNSKVICE VAHITLDRSP
       250        260        270        280        290        300
LRGIANLSNF IRVSPTVKVT QQSPTSMNQV NLTCRAERFY PEDLQLIWLE NGNVSRNDTP
       310        320        330        340        350        360
KNLTKNTDGT YNYTSLFLVN SSAHREDVVF TCQVKHDQQP AITRNHTVLG FAHSSDQGSM
       370        380        390        400        410        420
QTFPDNNATH NWNVFIGVGV ACALLVVLLM AALYLLRIKQ KKAKGSTSST RLHEPEKNAR
       430        440        450        460        470        480
EITQVQSLIQ DTNDINDITY ADLNLPKEKK PAPRAPEPNN HTEYASIETG KVPRPEDTLT
       490        500        510
YADLDMVHLS RAQPAPKPEP SFSEYASVQV QRK         10         20         30         40         50         60
MEPAGPAPGR LGPLLLCLLL SASCFCTGAT GKELKVTQPE KSVSVAAGDS TVLNCTLTSL
        70         80         90        100        110        120
LPVGPIRWYR GVGPSRLLIY SFAGEYVPRI RNVSDTTKRN NMDFSIRISN VTPADAGIYY
       130        140        150        160        170        180
CVKFQKGSSE PDTEIQSGGG TEVYVLAKPS PPEVSGPADR GIPDQKVNFT CKSHGFSPRN
       190        200        210        220        230        240
ITLKWFKDGQ ELHPLETTVN PSGKNVSYNI SSTVRVVLNS MDVNSKVICE VAHITLDRSP
       250        260        270        280        290        300
LRGIANLSNF IRVSPTVKVT QQSPTSMNQV NLTCRAERFY PEDLQLIWLE NGNVSRNDTP
       310        320        330        340        350        360
KNLTKNTDGT YNYTSLFLVN SSAHREDVVF TCQVKHDQQP AITRNHTVLG FAHSSDQGSM
       370        380        390        400        410        420
QTFPDNNATH NWNVFIGVGV ACALLVVLLM AALYLLRIKQ KKAKGSTSST RLHEPEKNAR
       430        440        450        460        470        480
EITQVQSLIQ DTNDINDITY ADLNLPKEKK PAPRAPEPNN HTEYASIETG KVPRPEDTLT
       490        500        510
YADLDMVHLS RAQPAPKPEP SFSEYASVQV QRK

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P97797-1-unknown	MEPAGP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89642
P97797-1-unknown	MEPAGP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89643
P97797-32-unknown	KELKVT...	32	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P97797-32-unknown	KELKVT...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114984
P97797-32-unknown	KELKVT...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114985

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QVQRK	513	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QVQRK	513	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85261
...QVQRK	513	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85260

TopFIND

P97797: Tyrosine-protein phosphatase non-receptor type substrate 1

General Information

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates