TopFIND 4.0

P97887: Presenilin-1

General Information

Protein names
- Presenilin-1
- PS-1
- 3.4.23.-
- Protein S182
- Presenilin-1 NTF subunit
- Presenilin-1 CTF subunit
- Presenilin-1 CTF12
- PS1-CTF12
Gene names Psen1
Organism Rattus norvegicus
Protease Family
Protease ID A22.001
Chromosome location
UniProt ID P97887

3

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTEIPAPLSY FQNAQMSEDS HSSSVRSQND NQERQQHHDR QRLDNPESIS NGRPQSNFTR 
        70         80         90        100        110        120 
QVIEQDEEED EELTLKYGAK HVIMLFVPVT LCMVVVVATI KSVSFYTRKD GQLIYTPFTE 
       130        140        150        160        170        180 
DTETVGQRAL HSILNAAIMI SVIVVMTILL VVLYKYRCYK VIHAWLIVSS LLLLFFFSFI 
       190        200        210        220        230        240 
YLGEVFKTYN VAVDYITVAL LIWNFGVVGM IAIHWKGPLR LQQAYLIMIS ALMALVFIKY 
       250        260        270        280        290        300 
LPEWTAWLIL AVISVYDLVA VLCPKGPLRM LVETAQERNE TLFPALIYSS TMVWLVNMAE 
       310        320        330        340        350        360 
GDPEAQRRVP KNPKYSTQGT EREETQDTGT GSDDGGFSEE WEAQRDSHLG PHRSTPESRA 
       370        380        390        400        410        420 
AVQELSGSIL TSEDPEERGV KLGLGDFIFY SVLVGKASAT ASGDWNTTIA CFVAILIGLC 
       430        440        450        460    
LTLLLLAIFK KALPALPISI TFGLIFYFAT DYLVQPFMDQ LAFHQFYI

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P97887-1-unknown MTEIPA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P97887-299-unknown AEGDPE... 299 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P97887-347-unknown SHLGPH... 347 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...WLVNMA 298 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HQFYI 468 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)