TopFIND 4.0

P98083: SHC-transforming protein 1

General Information

Protein names
- SHC-transforming protein 1
- SHC-transforming protein A
- Src homology 2 domain-containing-transforming protein C1
- SH2 domain protein C1
Gene names Shc1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P98083

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDLLPPKPKY NPLRNESLSS LEEGASGSTP PEELPSPSAS SLGPILPPLP GDDSPTTLCS 
        70         80         90        100        110        120 
FFPRMSNLKL ANPAGGRLGP KGEPGKAAED GEGSAGAALR DSGLLPLLQD MNKLSGGGGR 
       130        140        150        160        170        180 
RTRVEGGQLG GEEWTRHGSF VNKPTRGWLH PNDKVMGPGV SYLVRYMGCV EVLQSMRALD 
       190        200        210        220        230        240 
FNTRTQVTRE AISLVCEAVP GAKGATRRRK PCSRPLSSIL GRSNLKFAGM PITLTVSTSS 
       250        260        270        280        290        300 
LNLMAADCKQ IIANHHMQSI SFASGGDPDT AEYVAYVAKD PVNQRACHIL ECPEGLAQDV 
       310        320        330        340        350        360 
ISTIGQAFEL RFKQYLRNPP KLVTPHDRMA GFDGSAWDEE EEEPPDHQYY NDFPGKEPPL 
       370        380        390        400        410        420 
GGVVDMRLRE GAARPTLPSA QMSSHLGATL PIGQHAAGDH EVRKQMLPPP PCPGRELFDD 
       430        440        450        460        470        480 
PSYVNIQNLD KARQAGGGAG PPNPSLNGSA PRDLFDMKPF EDALRVPPPP QSMSMAEQLQ 
       490        500        510        520        530        540 
GEPWFHGKLS RREAEALLQL NGDFLVREST TTPGQYVLTG LQSGQPKHLL LVDPEGVVRT 
       550        560        570    
KDHRFESVSH LISYHMDNHL PIISAGSELC LQQPVDRKV

Isoforms

- Isoform p52Shc of SHC-transforming protein 1 - Isoform p47Shc of SHC-transforming protein 1

Sequence View

        10         20         30         40         50         60 
MDLLPPKPKY NPLRNESLSS LEEGASGSTP PEELPSPSAS SLGPILPPLP GDDSPTTLCS 
        70         80         90        100        110        120 
FFPRMSNLKL ANPAGGRLGP KGEPGKAAED GEGSAGAALR DSGLLPLLQD MNKLSGGGGR 
       130        140        150        160        170        180 
RTRVEGGQLG GEEWTRHGSF VNKPTRGWLH PNDKVMGPGV SYLVRYMGCV EVLQSMRALD 
       190        200        210        220        230        240 
FNTRTQVTRE AISLVCEAVP GAKGATRRRK PCSRPLSSIL GRSNLKFAGM PITLTVSTSS 
       250        260        270        280        290        300 
LNLMAADCKQ IIANHHMQSI SFASGGDPDT AEYVAYVAKD PVNQRACHIL ECPEGLAQDV 
       310        320        330        340        350        360 
ISTIGQAFEL RFKQYLRNPP KLVTPHDRMA GFDGSAWDEE EEEPPDHQYY NDFPGKEPPL 
       370        380        390        400        410        420 
GGVVDMRLRE GAARPTLPSA QMSSHLGATL PIGQHAAGDH EVRKQMLPPP PCPGRELFDD 
       430        440        450        460        470        480 
PSYVNIQNLD KARQAGGGAG PPNPSLNGSA PRDLFDMKPF EDALRVPPPP QSMSMAEQLQ 
       490        500        510        520        530        540 
GEPWFHGKLS RREAEALLQL NGDFLVREST TTPGQYVLTG LQSGQPKHLL LVDPEGVVRT 
       550        560        570    
KDHRFESVSH LISYHMDNHL PIISAGSELC LQQPVDRKV         10         20         30         40         50         60 
MDLLPPKPKY NPLRNESLSS LEEGASGSTP PEELPSPSAS SLGPILPPLP GDDSPTTLCS 
        70         80         90        100        110        120 
FFPRMSNLKL ANPAGGRLGP KGEPGKAAED GEGSAGAALR DSGLLPLLQD MNKLSGGGGR 
       130        140        150        160        170        180 
RTRVEGGQLG GEEWTRHGSF VNKPTRGWLH PNDKVMGPGV SYLVRYMGCV EVLQSMRALD 
       190        200        210        220        230        240 
FNTRTQVTRE AISLVCEAVP GAKGATRRRK PCSRPLSSIL GRSNLKFAGM PITLTVSTSS 
       250        260        270        280        290        300 
LNLMAADCKQ IIANHHMQSI SFASGGDPDT AEYVAYVAKD PVNQRACHIL ECPEGLAQDV 
       310        320        330        340        350        360 
ISTIGQAFEL RFKQYLRNPP KLVTPHDRMA GFDGSAWDEE EEEPPDHQYY NDFPGKEPPL 
       370        380        390        400        410        420 
GGVVDMRLRE GAARPTLPSA QMSSHLGATL PIGQHAAGDH EVRKQMLPPP PCPGRELFDD 
       430        440        450        460        470        480 
PSYVNIQNLD KARQAGGGAG PPNPSLNGSA PRDLFDMKPF EDALRVPPPP QSMSMAEQLQ 
       490        500        510        520        530        540 
GEPWFHGKLS RREAEALLQL NGDFLVREST TTPGQYVLTG LQSGQPKHLL LVDPEGVVRT 
       550        560        570    
KDHRFESVSH LISYHMDNHL PIISAGSELC LQQPVDRKV



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Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P98083-1-Acetylation MDLLPP... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P98083-111-unknown MNKLSG... 111 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89588
    P98083-111-unknown MNKLSG... 111 inferred from electronic annotation unknown TISdb inferred from TISdb
    P98083-156-unknown MGPGVS... 156 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89589
    P98083-156-unknown MGPGVS... 156 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt109506

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)