TopFIND 4.0

Q02083: N-acylethanolamine-hydrolyzing acid amidase

General Information

Protein names
- N-acylethanolamine-hydrolyzing acid amidase
- 3.5.1.- {ECO:0000269|PubMed:15655246, ECO:0000269|PubMed:17980170, ECO:0000269|PubMed:18793752, ECO:0000269|PubMed:22040171, ECO:0000269|PubMed:30301806}
- Acid ceramidase-like protein
- N-acylsphingosine amidohydrolase-like
- ASAH-like protein
- N-acylethanolamine-hydrolyzing acid amidase subunit alpha
- N-acylethanolamine-hydrolyzing acid amidase subunit beta
Gene names NAAA
Organism Homo sapiens
Protease Family
Protease ID C89.002
Chromosome location
UniProt ID Q02083

3

N-termini

4

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRTADREARP GLPSLLLLLL AGAGLSAASP PAAPRFNVSL DSVPELRWLP VLRHYDLDLV 
        70         80         90        100        110        120 
RAAMAQVIGD RVPKWVHVLI GKVVLELERF LPQPFTGEIR GMCDFMNLSL ADCLLVNLAY 
       130        140        150        160        170        180 
ESSVFCTSIV AQDSRGHIYH GRNLDYPFGN VLRKLTVDVQ FLKNGQIAFT GTTFIGYVGL 
       190        200        210        220        230        240 
WTGQSPHKFT VSGDERDKGW WWENAIAALF RRHIPVSWLI RATLSESENF EAAVGKLAKT 
       250        260        270        280        290        300 
PLIADVYYIV GGTSPREGVV ITRNRDGPAD IWPLDPLNGA WFRVETNYDH WKPAPKEDDR 
       310        320        330        340        350    
RTSAIKALNA TGQANLSLEA LFQILSVVPV YNNFTIYTTV MSAGSPDKYM TRIRNPSRK

Isoforms

- Isoform 2 of N-acylethanolamine-hydrolyzing acid amidase - Isoform 3 of N-acylethanolamine-hydrolyzing acid amidase

Sequence View

        10         20         30         40         50         60 
MRTADREARP GLPSLLLLLL AGAGLSAASP PAAPRFNVSL DSVPELRWLP VLRHYDLDLV 
        70         80         90        100        110        120 
RAAMAQVIGD RVPKWVHVLI GKVVLELERF LPQPFTGEIR GMCDFMNLSL ADCLLVNLAY 
       130        140        150        160        170        180 
ESSVFCTSIV AQDSRGHIYH GRNLDYPFGN VLRKLTVDVQ FLKNGQIAFT GTTFIGYVGL 
       190        200        210        220        230        240 
WTGQSPHKFT VSGDERDKGW WWENAIAALF RRHIPVSWLI RATLSESENF EAAVGKLAKT 
       250        260        270        280        290        300 
PLIADVYYIV GGTSPREGVV ITRNRDGPAD IWPLDPLNGA WFRVETNYDH WKPAPKEDDR 
       310        320        330        340        350    
RTSAIKALNA TGQANLSLEA LFQILSVVPV YNNFTIYTTV MSAGSPDKYM TRIRNPSRK         10         20         30         40         50         60 
MRTADREARP GLPSLLLLLL AGAGLSAASP PAAPRFNVSL DSVPELRWLP VLRHYDLDLV 
        70         80         90        100        110        120 
RAAMAQVIGD RVPKWVHVLI GKVVLELERF LPQPFTGEIR GMCDFMNLSL ADCLLVNLAY 
       130        140        150        160        170        180 
ESSVFCTSIV AQDSRGHIYH GRNLDYPFGN VLRKLTVDVQ FLKNGQIAFT GTTFIGYVGL 
       190        200        210        220        230        240 
WTGQSPHKFT VSGDERDKGW WWENAIAALF RRHIPVSWLI RATLSESENF EAAVGKLAKT 
       250        260        270        280        290        300 
PLIADVYYIV GGTSPREGVV ITRNRDGPAD IWPLDPLNGA WFRVETNYDH WKPAPKEDDR 
       310        320        330        340        350    
RTSAIKALNA TGQANLSLEA LFQILSVVPV YNNFTIYTTV MSAGSPDKYM TRIRNPSRK



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Directness:


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Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)