Q02153: Guanylate cyclase soluble subunit beta-1 {ECO:0000305}

General Information

Protein names	- Guanylate cyclase soluble subunit beta-1 {ECO:0000305} - GCS-beta-1 - 4.6.1.2 {ECO:0000269\|PubMed:1352257, ECO:0000269\|PubMed:23505436, ECO:0000269\|PubMed:24669844} - Guanylate cyclase soluble subunit beta-3 {ECO:0000303\|PubMed:1352257} - GCS-beta-3 - Soluble guanylate cyclase small subunit
Gene names	GUCY1B3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q02153

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform HSGC-2 of Guanylate cyclase soluble subunit beta-1 - Isoform 3 of Guanylate cyclase soluble subunit beta-1

Sequence View

        10         20         30         40         50         60
MYGFVNHALE LLVIRNYGPE VWEDIKKEAQ LDEEGQFLVR IIYDDSKTYD LVAAASKVLN
        70         80         90        100        110        120
LNAGEILQMF GKMFFVFCQE SGYDTILRVL GSNVREFLQN LDALHDHLAT IYPGMRAPSF
       130        140        150        160        170        180
RCTDAEKGKG LILHYYSERE GLQDIVIGII KTVAQQIHGT EIDMKVIQQR NEECDHTQFL
       190        200        210        220        230        240
IEEKESKEED FYEDLDRFEE NGTQESRISP YTFCKAFPFH IIFDRDLVVT QCGNAIYRVL
       250        260        270        280        290        300
PQLQPGNCSL LSVFSLVRPH IDISFHGILS HINTVFVLRS KEGLLDVEKL ECEDELTGTE
       310        320        330        340        350        360
ISCLRLKGQM IYLPEADSIL FLCSPSVMNL DDLTRRGLYL SDIPLHDATR DLVLLGEQFR
       370        380        390        400        410        420
EEYKLTQELE ILTDRLQLTL RALEDEKKKT DTLLYSVLPP SVANELRHKR PVPAKRYDNV
       430        440        450        460        470        480
TILFSGIVGF NAFCSKHASG EGAMKIVNLL NDLYTRFDTL TDSRKNPFVY KVETVGDKYM
       490        500        510        520        530        540
TVSGLPEPCI HHARSICHLA LDMMEIAGQV QVDGESVQIT IGIHTGEVVT GVIGQRMPRY
       550        560        570        580        590        600
CLFGNTVNLT SRTETTGEKG KINVSEYTYR CLMSPENSDP QFHLEHRGPV SMKGKKEPMQ
       610
VWFLSRKNTG TEETKQDDD         10         20         30         40         50         60
MYGFVNHALE LLVIRNYGPE VWEDIKKEAQ LDEEGQFLVR IIYDDSKTYD LVAAASKVLN
        70         80         90        100        110        120
LNAGEILQMF GKMFFVFCQE SGYDTILRVL GSNVREFLQN LDALHDHLAT IYPGMRAPSF
       130        140        150        160        170        180
RCTDAEKGKG LILHYYSERE GLQDIVIGII KTVAQQIHGT EIDMKVIQQR NEECDHTQFL
       190        200        210        220        230        240
IEEKESKEED FYEDLDRFEE NGTQESRISP YTFCKAFPFH IIFDRDLVVT QCGNAIYRVL
       250        260        270        280        290        300
PQLQPGNCSL LSVFSLVRPH IDISFHGILS HINTVFVLRS KEGLLDVEKL ECEDELTGTE
       310        320        330        340        350        360
ISCLRLKGQM IYLPEADSIL FLCSPSVMNL DDLTRRGLYL SDIPLHDATR DLVLLGEQFR
       370        380        390        400        410        420
EEYKLTQELE ILTDRLQLTL RALEDEKKKT DTLLYSVLPP SVANELRHKR PVPAKRYDNV
       430        440        450        460        470        480
TILFSGIVGF NAFCSKHASG EGAMKIVNLL NDLYTRFDTL TDSRKNPFVY KVETVGDKYM
       490        500        510        520        530        540
TVSGLPEPCI HHARSICHLA LDMMEIAGQV QVDGESVQIT IGIHTGEVVT GVIGQRMPRY
       550        560        570        580        590        600
CLFGNTVNLT SRTETTGEKG KINVSEYTYR CLMSPENSDP QFHLEHRGPV SMKGKKEPMQ
       610
VWFLSRKNTG TEETKQDDD

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q02153-1-unknown	MYGFVN...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q02153-1-unknown	MYGFVN...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75824
Q02153-69-unknown	MFGKMF...	69	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000427226
Q02153-69-unknown	MFGKMF...	69	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000422313
Q02153-69-unknown	MFGKMF...	69	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000425065
Q02153-69-unknown	MFGKMF...	69	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196463
Q02153-69-unknown	MFGKMF...	69	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196464

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KQDDD	619	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KQDDD	619	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71442
...KQDDD	619	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71443

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)