Q02318: Sterol 26-hydroxylase, mitochondrial {ECO:0000250|UniProtKB:P17177}
| Protein names | - Sterol 26-hydroxylase, mitochondrial {ECO:0000250|UniProtKB:P17177} - 1.14.15.15 {ECO:0000269|PubMed:11412116, ECO:0000269|PubMed:1708392, ECO:0000269|PubMed:2019602, ECO:0000269|PubMed:7915755, ECO:0000269|PubMed:9186905, ECO:0000269|PubMed:9790667} - 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase {ECO:0000303|PubMed:1708392} - Cytochrome P-450C27/25 - Cytochrome P450 27 - Sterol 27-hydroxylase {ECO:0000303|PubMed:1708392} - Vitamin D(3) 25-hydroxylase {ECO:0000303|PubMed:15465040} |
|---|---|
| Gene names | CYP27A1 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q02318 |
2
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAALGCARLR WALRGAGRGL CPHGARAKAA IPAALPSDKA TGAPGAGPGV RRRQRSLEEI
70 80 90 100 110 120
PRLGQLRFFF QLFVQGYALQ LHQLQVLYKA KYGPMWMSYL GPQMHVNLAS APLLEQVMRQ
130 140 150 160 170 180
EGKYPVRNDM ELWKEHRDQH DLTYGPFTTE GHHWYQLRQA LNQRLLKPAE AALYTDAFNE
190 200 210 220 230 240
VIDDFMTRLD QLRAESASGN QVSDMAQLFY YFALEAICYI LFEKRIGCLQ RSIPEDTVTF
250 260 270 280 290 300
VRSIGLMFQN SLYATFLPKW TRPVLPFWKR YLDGWNAIFS FGKKLIDEKL EDMEAQLQAA
310 320 330 340 350 360
GPDGIQVSGY LHFLLASGQL SPREAMGSLP ELLMAGVDTT SNTLTWALYH LSKDPEIQEA
370 380 390 400 410 420
LHEEVVGVVP AGQVPQHKDF AHMPLLKAVL KETLRLYPVV PTNSRIIEKE IEVDGFLFPK
430 440 450 460 470 480
NTQFVFCHYV VSRDPTAFSE PESFQPHRWL RNSQPATPRI QHPFGSVPFG YGVRACLGRR
490 500 510 520 530
IAELEMQLLL ARLIQKYKVV LAPETGELKS VARIVLVPNK KVGLQFLQRQ C
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q02318-34-unknown | ALPSDK... | 34 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q02318-95-unknown | MWMSYL... | 95 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000392671 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LHFLLA | 315 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000392671 | |||
| ...LQRQC | 531 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|