TopFIND 4.0

Q02401: Lactase-phlorizin hydrolase

General Information

Protein names
- Lactase-phlorizin hydrolase
- Lactase-glycosylceramidase
- Lactase
- 3.2.1.108
- Phlorizin hydrolase
- 3.2.1.62
Gene names Lct
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q02401

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MELPWTALFL STVLLGLSCQ GSDWESDRNF ISAAGPLTND LVLNLNYPPG KQGSDVVSGN 
        70         80         90        100        110        120 
TDHLLCQQPL PSFLSQYFSS LRASQVTHYK VLLSWAQLLP TGSSKNPDQE AVQCYRQLLQ 
       130        140        150        160        170        180 
SLKDAQLEPM VVLCHQTPPT SSAIQREGAF ADLFADYATL AFQSFGDLVE IWFTFSDLEK 
       190        200        210        220        230        240 
VIMDLPHKDL KASALQTLSN AHRRAFEIYH RKFSSQGGKL SVVLKAEDIP ELLPDPALAA 
       250        260        270        280        290        300 
LVQGSVDFLS LDLSYECQSV ATLPQKLSEL QNLEPKVKVF IYTLKLEDCP ATGTSPSSLL 
       310        320        330        340        350        360 
ISLLEAINKD QIQTVGFDVN AFLSCTSNSE ESPSCSLTDS LALQTEQQQE TAVPSSPGSA 
       370        380        390        400        410        420 
YQRVWAAFAN QSREERDAFL QDVFPEGFLW GISTGAFNVE GGWAEGGRGP SIWDHYGNLN 
       430        440        450        460        470        480 
AAEGQATAKV ASDSYHKPAS DVALLRGIRA QVYKFSISWS GLFPLGQKST PNRQGVAYYN 
       490        500        510        520        530        540 
KLIDRLLDSH IEPMATLFHW DLPQALQEQG GWQNESVVEA FLDYAAFCFS TFGDRVKLWV 
       550        560        570        580        590        600 
TFHEPWVMSY AGYGTGQHAP AISDPGMASF KVAHLILKAH ARTWHLYDLH HRLQQQGRVG 
       610        620        630        640        650        660 
IVLNSDLAEP LDRKSPQDLA AAERFLHFML GWFAHPIFVD GDYPTTSAQI QHINQQCGHP 
       670        680        690        700        710        720 
LAQLPEFTEA EKRLLKGSAD FLGLSHYTSR LISKAGRQTC TSSYDNIGGF SQHVDPEWPQ 
       730        740        750        760        770        780 
TASPWIRVVP WGIRRLLRFA SMEYTKGKLP IFLAGNGMPV GEEADLFDDS VRVNYFNWYI 
       790        800        810        820        830        840 
NEVLKAVKED LVDVRSYIVR SLIDGYEGPL GFSQRFGLYH VNFNDSSRPR TPRKSAYLFT 
       850        860        870        880        890        900 
SIIEKNGFSA KKVKRNPLPV RADFTSRARV TDSLPSEVPS KAKISVEKFS KQPRFERDLF 
       910        920        930        940        950        960 
YDGRFRDDFL WGVSSSPYQI EGGWNADGKG PSIWDNFTHT PGNGVKDNAT GDVACDSYHQ 
       970        980        990       1000       1010       1020 
LDADLNILRT LKVKSYRFSI SWSRIFPTGR NSTINKQGVD YYNRLIDSLV DNNIFPMVTL 
      1030       1040       1050       1060       1070       1080 
FHWDLPQALQ DIGGWENPSL IELFDSYADY CFKTFGDRVK FWMTFNEPWC HVVLGYSSGI 
      1090       1100       1110       1120       1130       1140 
FPPSVQEPGW LPYKVSHIVI KAHARVYHTY DEKYRSEQKG VISLSLNTHW AEPKDPGLQR 
      1150       1160       1170       1180       1190       1200 
DVEAADRMLQ FTMGWFAHPI FKNGDYPDVM KWTVGNRSEL QHLASSRLPT FTEEEKNYVR 
      1210       1220       1230       1240       1250       1260 
GTADVFCHNT YTSVFVQHST PRLNPPSYDD DMELKLIEMN SSTGVMHQDV PWGTRRLLNW 
      1270       1280       1290       1300       1310       1320 
IKEEYGNIPI YITENGQGLE NPTLDDTERI FYHKTYINEA LKAYKLDGVD LRGYSAWTLM 
      1330       1340       1350       1360       1370       1380 
DDFEWLLGYT MRFGLYYVDF NHVSRPRTAR ASARYYPDLI ANNGMPLARE DEFLYGEFPK 
      1390       1400       1410       1420       1430       1440 
GFIWSAASAS YQVEGAWRAD GKGLSIWDTF SHTPLRIGND DNGDVACDSY HKIAEDVVAL 
      1450       1460       1470       1480       1490       1500 
QNLGVSHYRF SIAWSRILPD GTTKFINEAG LSYYVRFIDA LLAAGITPQV TIYHWDLPQA 
      1510       1520       1530       1540       1550       1560 
LQDVGGWENE TIVQRFKEYA DVLFQRLGDR VKFWITLNEP FVIAAQGYGT GVSAPGISFR 
      1570       1580       1590       1600       1610       1620 
PGTAPYIAGH NLIKAHAEAW HLYNDVYRAR QGGTISITIS SDWGEPRDPT NREHVEAARS 
      1630       1640       1650       1660       1670       1680 
YVQFMGGWFA HPIFKNGDYP EVMKTRIRDR SLGAGLNKSR LPEFTESEKS RIKGTFDFFG 
      1690       1700       1710       1720       1730       1740 
FNHNTTVLAY NLDYPAAFSS FDADRGVASI ADSSWPVSGS FWLKVTPFGF RRILNWLKEE 
      1750       1760       1770       1780       1790       1800 
YNNPPIYVTE NGVSRRGEPE LNDTDRIYYL RSYINEALKA VHDKVDLRGY TVWSIMDNFE 
      1810       1820       1830       1840       1850       1860 
WATGFAERFG VHFVNRSDPS LPRIPRASAK FYATIVRCNG FPDPAQGPHP CLQQPEDAAP 
      1870       1880       1890       1900       1910       1920 
TASPVQSEVP FLGLMLGIAE AQTALYVLFA LLLLGACSLA FLTYNTGRRS KQGNAQPSQH 
   
QLSPISSF

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q02401-868-unknown ARVTDS... 868 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PISSF 1928 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)