Q03347: Runt-related transcription factor 1
| Protein names | - Runt-related transcription factor 1 - Acute myeloid leukemia 1 protein - Core-binding factor subunit alpha-2 - CBF-alpha-2 - Oncogene AML-1 - Polyomavirus enhancer-binding protein 2 alpha B subunit - PEA2-alpha B - PEBP2-alpha B - SL3-3 enhancer factor 1 alpha B subunit - SL3/AKV core-binding factor alpha B subunit |
|---|---|
| Gene names | Runx1 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q03347 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MRIPVDASTS RRFTPPSTAL SPGKMSEALP LGAPDGGPAL ASKLRSGDRS MVEVLADHPG
70 80 90 100 110 120
ELVRTDSPNF LCSVLPTHWR CNKTLPIAFK VVALGDVPDG TLVTVMAGND ENYSAELRNA
130 140 150 160 170 180
TAAMKNQVAR FNDLRFVGRS GRGKSFTLTI TVFTNPPQVA TYHRAIKITV DGPREPRRHR
190 200 210 220 230 240
QKLDDQTKPG SLSFSERLSE LEQLRRTAMR VSPHHPAPTP NPRASLNHST AFNPQPQSQM
250 260 270 280 290 300
QDARQIQPSP PWSYDQSYQY LGSITSSSVH PATPISPGRA SGMTSLSAEL SSRLSTAPDL
310 320 330 340 350 360
TAFGDPRQFP TLPSISDPRM HYPGAFTYSP PVTSGIGIGM SAMSSASRYH TYLPPPYPGS
370 380 390 400 410 420
SQAQAGPFQT GSPSYHLYYG ASAGSYQFSM VGGERSPPRI LPPCTNASTG AALLNPSLPS
430 440 450
QSDVVETEGS HSNSPTNMPP ARLEEAVWRP Y
Isoforms
- Isoform 2 of Runt-related transcription factor 1 - Isoform 3 of Runt-related transcription factor 1 - Isoform 4 of Runt-related transcription factor 1 - Isoform 5 of Runt-related transcription factor 1Sequence View
10 20 30 40 50 60
MRIPVDASTS RRFTPPSTAL SPGKMSEALP LGAPDGGPAL ASKLRSGDRS MVEVLADHPG
70 80 90 100 110 120
ELVRTDSPNF LCSVLPTHWR CNKTLPIAFK VVALGDVPDG TLVTVMAGND ENYSAELRNA
130 140 150 160 170 180
TAAMKNQVAR FNDLRFVGRS GRGKSFTLTI TVFTNPPQVA TYHRAIKITV DGPREPRRHR
190 200 210 220 230 240
QKLDDQTKPG SLSFSERLSE LEQLRRTAMR VSPHHPAPTP NPRASLNHST AFNPQPQSQM
250 260 270 280 290 300
QDARQIQPSP PWSYDQSYQY LGSITSSSVH PATPISPGRA SGMTSLSAEL SSRLSTAPDL
310 320 330 340 350 360
TAFGDPRQFP TLPSISDPRM HYPGAFTYSP PVTSGIGIGM SAMSSASRYH TYLPPPYPGS
370 380 390 400 410 420
SQAQAGPFQT GSPSYHLYYG ASAGSYQFSM VGGERSPPRI LPPCTNASTG AALLNPSLPS
430 440 450
QSDVVETEGS HSNSPTNMPP ARLEEAVWRP Y
10 20 30 40 50 60
MRIPVDASTS RRFTPPSTAL SPGKMSEALP LGAPDGGPAL ASKLRSGDRS MVEVLADHPG
70 80 90 100 110 120
ELVRTDSPNF LCSVLPTHWR CNKTLPIAFK VVALGDVPDG TLVTVMAGND ENYSAELRNA
130 140 150 160 170 180
TAAMKNQVAR FNDLRFVGRS GRGKSFTLTI TVFTNPPQVA TYHRAIKITV DGPREPRRHR
190 200 210 220 230 240
QKLDDQTKPG SLSFSERLSE LEQLRRTAMR VSPHHPAPTP NPRASLNHST AFNPQPQSQM
250 260 270 280 290 300
QDARQIQPSP PWSYDQSYQY LGSITSSSVH PATPISPGRA SGMTSLSAEL SSRLSTAPDL
310 320 330 340 350 360
TAFGDPRQFP TLPSISDPRM HYPGAFTYSP PVTSGIGIGM SAMSSASRYH TYLPPPYPGS
370 380 390 400 410 420
SQAQAGPFQT GSPSYHLYYG ASAGSYQFSM VGGERSPPRI LPPCTNASTG AALLNPSLPS
430 440 450
QSDVVETEGS HSNSPTNMPP ARLEEAVWRP Y
10 20 30 40 50 60
MRIPVDASTS RRFTPPSTAL SPGKMSEALP LGAPDGGPAL ASKLRSGDRS MVEVLADHPG
70 80 90 100 110 120
ELVRTDSPNF LCSVLPTHWR CNKTLPIAFK VVALGDVPDG TLVTVMAGND ENYSAELRNA
130 140 150 160 170 180
TAAMKNQVAR FNDLRFVGRS GRGKSFTLTI TVFTNPPQVA TYHRAIKITV DGPREPRRHR
190 200 210 220 230 240
QKLDDQTKPG SLSFSERLSE LEQLRRTAMR VSPHHPAPTP NPRASLNHST AFNPQPQSQM
250 260 270 280 290 300
QDARQIQPSP PWSYDQSYQY LGSITSSSVH PATPISPGRA SGMTSLSAEL SSRLSTAPDL
310 320 330 340 350 360
TAFGDPRQFP TLPSISDPRM HYPGAFTYSP PVTSGIGIGM SAMSSASRYH TYLPPPYPGS
370 380 390 400 410 420
SQAQAGPFQT GSPSYHLYYG ASAGSYQFSM VGGERSPPRI LPPCTNASTG AALLNPSLPS
430 440 450
QSDVVETEGS HSNSPTNMPP ARLEEAVWRP Y
10 20 30 40 50 60
MRIPVDASTS RRFTPPSTAL SPGKMSEALP LGAPDGGPAL ASKLRSGDRS MVEVLADHPG
70 80 90 100 110 120
ELVRTDSPNF LCSVLPTHWR CNKTLPIAFK VVALGDVPDG TLVTVMAGND ENYSAELRNA
130 140 150 160 170 180
TAAMKNQVAR FNDLRFVGRS GRGKSFTLTI TVFTNPPQVA TYHRAIKITV DGPREPRRHR
190 200 210 220 230 240
QKLDDQTKPG SLSFSERLSE LEQLRRTAMR VSPHHPAPTP NPRASLNHST AFNPQPQSQM
250 260 270 280 290 300
QDARQIQPSP PWSYDQSYQY LGSITSSSVH PATPISPGRA SGMTSLSAEL SSRLSTAPDL
310 320 330 340 350 360
TAFGDPRQFP TLPSISDPRM HYPGAFTYSP PVTSGIGIGM SAMSSASRYH TYLPPPYPGS
370 380 390 400 410 420
SQAQAGPFQT GSPSYHLYYG ASAGSYQFSM VGGERSPPRI LPPCTNASTG AALLNPSLPS
430 440 450
QSDVVETEGS HSNSPTNMPP ARLEEAVWRP Y
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q03347-1-unknown | MRIPVD... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q03347-1-unknown | MRIPVD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt88416 | |||
| Q03347-1-unknown | MRIPVD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt88417 | |||
| Q03347-1-unknown | MRIPVD... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt88419 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...VWRPY | 451 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...VWRPY | 451 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt84034 | |||
| ...VWRPY | 451 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt84036 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|