TopFIND 4.0

Q03963: Interferon-induced, double-stranded RNA-activated protein kinase

General Information

Protein names
- Interferon-induced, double-stranded RNA-activated protein kinase
- 2.7.11.1
- Eukaryotic translation initiation factor 2-alpha kinase 2
- eIF-2A protein kinase 2
- Interferon-inducible RNA-dependent protein kinase
- P1/eIF-2A protein kinase
- Protein kinase RNA-activated
- PKR
- Protein kinase R {ECO:0000303|PubMed:20478537}
- Serine/threonine-protein kinase TIK
- Tyrosine-protein kinase EIF2AK2
- 2.7.10.2
- p68 kinase
Gene names Eif2ak2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q03963

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASDTPGFYM DKLNKYRQMH GVAITYKELS TSGPPHDRRF TFQVLIDEKE FPEAKGRSKQ 
        70         80         90        100        110        120 
EARNAAAKLA VDILDNENKV DCHTSASEQG LFVGNYIGLV NSFAQKKKLS VNYEQCEPNS 
       130        140        150        160        170        180 
ELPQRFICKC KIGQTMYGTG SGVTKQEAKQ LAAKEAYQKL LKSPPKTAGT SSSVVTSTFS 
       190        200        210        220        230        240 
GFSSSSSMTS NGVSQSAPGS FSSENVFTNG LGENKRKSGV KVSPDDVQRN KYTLDARFNS 
       250        260        270        280        290        300 
DFEDIEEIGL GGFGQVFKAK HRIDGKRYAI KRVKYNTEKA EHEVQALAEL NHVNIVQYHS 
       310        320        330        340        350        360 
CWEGVDYDPE HSMSDTSRYK TRCLFIQMEF CDKGTLEQWM RNRNQSKVDK ALILDLYEQI 
       370        380        390        400        410        420 
VTGVEYIHSK GLIHRDLKPG NIFLVDERHI KIGDFGLATA LENDGKSRTR RTGTLQYMSP 
       430        440        450        460        470        480 
EQLFLKHYGK EVDIFALGLI LAELLHTCFT ESEKIKFFES LRKGDFSNDI FDNKEKSLLK 
       490        500        510    
KLLSEKPKDR PETSEILKTL AEWRNISEKK KRNTC

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KRNTC 515 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)