Q04771: Activin receptor type-1

General Information

Protein names	- Activin receptor type-1 - 2.7.11.30 - Activin receptor type I - ACTR-I - Activin receptor-like kinase 2 - ALK-2 - Serine/threonine-protein kinase receptor R1 - SKR1 - TGF-B superfamily receptor type I - TSR-I
Gene names	ACVR1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q04771

1 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVDGVMILPV LIMIALPSPS MEDEKPKVNP KLYMCVCEGL SCGNEDHCEG QQCFSSLSIN
        70         80         90        100        110        120
DGFHVYQKGC FQVYEQGKMT CKTPPSPGQA VECCQGDWCN RNITAQLPTK GKSFPGTQNF
       130        140        150        160        170        180
HLEVGLIILS VVFAVCLLAC LLGVALRKFK RRNQERLNPR DVEYGTIEGL ITTNVGDSTL
       190        200        210        220        230        240
ADLLDHSCTS GSGSGLPFLV QRTVARQITL LECVGKGRYG EVWRGSWQGE NVAVKIFSSR
       250        260        270        280        290        300
DEKSWFRETE LYNTVMLRHE NILGFIASDM TSRHSSTQLW LITHYHEMGS LYDYLQLTTL
       310        320        330        340        350        360
DTVSCLRIVL SIASGLAHLH IEIFGTQGKP AIAHRDLKSK NILVKKNGQC CIADLGLAVM
       370        380        390        400        410        420
HSQSTNQLDV GNNPRVGTKR YMAPEVLDET IQVDCFDSYK RVDIWAFGLV LWEVARRMVS
       430        440        450        460        470        480
NGIVEDYKPP FYDVVPNDPS FEDMRKVVCV DQQRPNIPNR WFSDPTLTSL AKLMKECWYQ
       490        500
NPSARLTALR IKKTLTKIDN SLDKLKTDC

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q04771-21-unknown	MEDEKP...	21		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q04771-21-unknown	MEDEKP...	21		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PSPSME	21	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399322
...QKGCFQ	71	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000400767
...KGCFQV	72	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440091
...KTPPSP	86	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000401189
...TPPSPG	87	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000403006
...LKTDC	509	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)