TopFIND 4.0

Q04859: Serine/threonine-protein kinase MAK

General Information

Protein names
- Serine/threonine-protein kinase MAK
- 2.7.11.1 {ECO:0000250|UniProtKB:P20794}
- Male germ cell-associated kinase
- Protein kinase RCK
Gene names Mak
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q04859

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MNRYTTMKQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 
        70         80         90        100        110        120 
NVIKLKEVIR ENDHLYFVFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 
       130        140        150        160        170        180 
FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 
       190        200        210        220        230        240 
IDVWAVGSIM AELYTFRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ 
       250        260        270        280        290        300 
CIPINLKTLI PNASSEAIQL MTEMLNWDPK KRPTASQALK HPYFQVGQVL GSSAHHLDTK 
       310        320        330        340        350        360 
QTLHKQLQPL EPKPSSSERD PKPLPNILDQ PAGQPQPKQG HQPLQTIQPP QNTVTHPPPK 
       370        380        390        400        410        420 
QQGHQKPPQT MFPSIIKTIP VNSVSTLGHK GARRRWGQTV FKSGDSCDDI EDDLGASHSK 
       430        440        450        460        470        480 
KPSMEACKEK KKESPFRFPD SGLPVSNHFK GENRNLHASV SLKSDPNLST ASTAKQYYLK 
       490        500        510        520        530        540 
QSRYLPGVNP KNVSLVAGGK DINSHSWNNQ LFPKSLGSMG ADLSFKRSNA AGNLGSYTTY 
       550        560        570        580        590        600 
NQTGYMPSFL KKEVGSAGQR IQLAPLGASA SDYTWSTKTG RGQFSGRTYN PTAKNLNIVN 
       610        620    
RTQPVPSVHG RTDWVAKYGG HR

Isoforms

- Isoform 2 of Serine/threonine-protein kinase MAK - Isoform 3 of Serine/threonine-protein kinase MAK

Sequence View

        10         20         30         40         50         60 
MNRYTTMKQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 
        70         80         90        100        110        120 
NVIKLKEVIR ENDHLYFVFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 
       130        140        150        160        170        180 
FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 
       190        200        210        220        230        240 
IDVWAVGSIM AELYTFRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ 
       250        260        270        280        290        300 
CIPINLKTLI PNASSEAIQL MTEMLNWDPK KRPTASQALK HPYFQVGQVL GSSAHHLDTK 
       310        320        330        340        350        360 
QTLHKQLQPL EPKPSSSERD PKPLPNILDQ PAGQPQPKQG HQPLQTIQPP QNTVTHPPPK 
       370        380        390        400        410        420 
QQGHQKPPQT MFPSIIKTIP VNSVSTLGHK GARRRWGQTV FKSGDSCDDI EDDLGASHSK 
       430        440        450        460        470        480 
KPSMEACKEK KKESPFRFPD SGLPVSNHFK GENRNLHASV SLKSDPNLST ASTAKQYYLK 
       490        500        510        520        530        540 
QSRYLPGVNP KNVSLVAGGK DINSHSWNNQ LFPKSLGSMG ADLSFKRSNA AGNLGSYTTY 
       550        560        570        580        590        600 
NQTGYMPSFL KKEVGSAGQR IQLAPLGASA SDYTWSTKTG RGQFSGRTYN PTAKNLNIVN 
       610        620    
RTQPVPSVHG RTDWVAKYGG HR         10         20         30         40         50         60 
MNRYTTMKQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 
        70         80         90        100        110        120 
NVIKLKEVIR ENDHLYFVFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 
       130        140        150        160        170        180 
FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 
       190        200        210        220        230        240 
IDVWAVGSIM AELYTFRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ 
       250        260        270        280        290        300 
CIPINLKTLI PNASSEAIQL MTEMLNWDPK KRPTASQALK HPYFQVGQVL GSSAHHLDTK 
       310        320        330        340        350        360 
QTLHKQLQPL EPKPSSSERD PKPLPNILDQ PAGQPQPKQG HQPLQTIQPP QNTVTHPPPK 
       370        380        390        400        410        420 
QQGHQKPPQT MFPSIIKTIP VNSVSTLGHK GARRRWGQTV FKSGDSCDDI EDDLGASHSK 
       430        440        450        460        470        480 
KPSMEACKEK KKESPFRFPD SGLPVSNHFK GENRNLHASV SLKSDPNLST ASTAKQYYLK 
       490        500        510        520        530        540 
QSRYLPGVNP KNVSLVAGGK DINSHSWNNQ LFPKSLGSMG ADLSFKRSNA AGNLGSYTTY 
       550        560        570        580        590        600 
NQTGYMPSFL KKEVGSAGQR IQLAPLGASA SDYTWSTKTG RGQFSGRTYN PTAKNLNIVN 
       610        620    
RTQPVPSVHG RTDWVAKYGG HR



Filter Information:


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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q04859-1-unknown MNRYTT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q04859-1-unknown MNRYTT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80338
    Q04859-1-unknown MNRYTT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80339

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)