TopFIND 4.0

Q05511: Serine protease hepsin

General Information

Protein names
- Serine protease hepsin
- 3.4.21.106 {ECO:0000250|UniProtKB:P05981}
- Serine protease hepsin non-catalytic chain
- Serine protease hepsin catalytic chain
Gene names Hpn
Organism Rattus norvegicus
Protease Family
Protease ID S01.224
Chromosome location
UniProt ID Q05511

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAKEGGRTAP CCSRPKVAAL TVGTLLFLTG IGAASWAIVT ILLRSDQEPL YQVQLSPGDS 
        70         80         90        100        110        120 
RLLVLDKTEG TWRLLCSSRS NARVAGLGCE EMGFLRALAH SELDVRTAGA NGTSGFFCVD 
       130        140        150        160        170        180 
EGGLPLAQRL LDVISVCDCP RGRFLTATCQ DCGRRKLPVD RIVGGQDSSL GRWPWQVSLR 
       190        200        210        220        230        240 
YDGTHLCGGS LLSGDWVLTA AHCFPERNRV LSRWRVFAGA VARTSPHAVQ LGVQAVIYHG 
       250        260        270        280        290        300 
GYLPFRDPTI DENSNDIALV HLSSSLPLTE YIQPVCLPAA GQALVDGKVC TVTGWGNTQF 
       310        320        330        340        350        360 
YGQQAVVLQE ARVPIISNEV CNSPDFYGNQ IKPKMFCAGY PEGGIDACQG DSGGHFVCED 
       370        380        390        400        410    
RISGTSRWRL CGIVSWGTGC ALARKPGVYT KVIDFREWIF QAIKTHSEAT GMVTQP

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q05511-1-unknown MAKEGG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q05511-162-unknown IVGGQD... 162 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LPVDRI 161 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...MVTQP 416 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)