TopFIND 4.0

Q05580: E3 ubiquitin-protein ligase HEL2 {ECO:0000305|PubMed:22570702}

General Information

Protein names
- E3 ubiquitin-protein ligase HEL2 {ECO:0000305|PubMed:22570702}
- 2.3.2.27 {ECO:0000269|PubMed:22570702}
- Histone E3 ligase 2 {ECO:0000303|PubMed:22570702}
- RING-type E3 ubiquitin transferase HEL2 {ECO:0000305}
Gene names
Organism Saccharomyces cerevisiae
Protease Family
Protease ID
Chromosome location
UniProt ID Q05580

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSESVKENVT PTRNFRRTQG PQNNTKPHND RKNFRRKQKK NNLSAEPNLT TSSADDTDEE 
        70         80         90        100        110        120 
NELCVICARK LTYVSLTPCH HKTCHICGFR QRALYNKKSC LICRTENEEV MFTDRIDGDI 
       130        140        150        160        170        180 
SDKYNFCEKN EKYGINFTSE EVATETLNLL KFFCPLSKDE QVCDFGSFKK YNEHLKSEHN 
       190        200        210        220        230        240 
RMICLICATH KHAFPCELEI FTQNQLRNHQ TKGNSEGFKG HPMCAFCSGK RFYSDDELYI 
       250        260        270        280        290        300 
HMRNQHEKCH ICDKMNPASP QYFKDYNQLF DHFKHSHYVC TVQTCLDNKF VVFKDELELQ 
       310        320        330        340        350        360 
AHILQEHGNI LKGKPKFFQS ELSTFISAPS RVIRERDDYD LPSISSLPGS SSGSRTDVRS 
       370        380        390        400        410        420 
ASSPEESRLR LAERAKYYLE NSKEDFNKFS SYNEDYSKGR LSAEKLLESY KLLFTKPNAD 
       430        440        450        460        470        480 
VYLLIHNLAE TFPKNSSKYN NLNAIYEQRE QTLARQTSLP SLSSDSSLSM SIGRGHWGGT 
       490        500        510        520        530        540 
NDGGSAGAAL GVRNIKNLPT LKSPSASYDP FATTVKKNTL RPVQNIKRTT PQSVSYRTST 
       550        560        570        580        590        600 
NTVAFSPTYL ESKKGSSSTS LNNSKDKLKS LNLPQLPPPK PKVQIPGLNR PQIADPKQWG 
       610        620        630    
KKSSTQDTNV HDNLRELNTT SGGNKKKGKQ KQLLFHIGV

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q05580-2-unknown MSESVK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q05580-2-Acetylation SESVKE... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...FHIGV 639 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)