TopFIND 4.0

Q05769: Prostaglandin G/H synthase 2

General Information

Protein names
- Prostaglandin G/H synthase 2
- 1.14.99.1
- Cyclooxygenase-2
- COX-2
- Glucocorticoid-regulated inflammatory cyclooxygenase
- Gripghs
- Macrophage activation-associated marker protein P71/73
- PES-2
- PHS II
- Prostaglandin H2 synthase 2
- PGH synthase 2
- PGHS-2
- Prostaglandin-endoperoxide synthase 2
- TIS10 protein
Gene names Ptgs2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q05769

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLFRAVLLCA ALGLSQAANP CCSNPCQNRG ECMSTGFDQY KCDCTRTGFY GENCTTPEFL 
        70         80         90        100        110        120 
TRIKLLLKPT PNTVHYILTH FKGVWNIVNN IPFLRSLIMK YVLTSRSYLI DSPPTYNVHY 
       130        140        150        160        170        180 
GYKSWEAFSN LSYYTRALPP VADDCPTPMG VKGNKELPDS KEVLEKVLLR REFIPDPQGS 
       190        200        210        220        230        240 
NMMFAFFAQH FTHQFFKTDH KRGPGFTRGL GHGVDLNHIY GETLDRQHKL RLFKDGKLKY 
       250        260        270        280        290        300 
QVIGGEVYPP TVKDTQVEMI YPPHIPENLQ FAVGQEVFGL VPGLMMYATI WLREHNRVCD 
       310        320        330        340        350        360 
ILKQEHPEWG DEQLFQTSRL ILIGETIKIV IEDYVQHLSG YHFKLKFDPE LLFNQQFQYQ 
       370        380        390        400        410        420 
NRIASEFNTL YHWHPLLPDT FNIEDQEYSF KQFLYNNSIL LEHGLTQFVE SFTRQIAGRV 
       430        440        450        460        470        480 
AGGRNVPIAV QAVAKASIDQ SREMKYQSLN EYRKRFSLKP YTSFEELTGE KEMAAELKAL 
       490        500        510        520        530        540 
YSDIDVMELY PALLVEKPRP DAIFGETMVE LGAPFSLKGL MGNPICSPQY WKPSTFGGEV 
       550        560        570        580        590        600 
GFKIINTASI QSLICNNVKG CPFTSFNVQD PQPTKTATIN ASASHSRLDD INPTVLIKRR 
   
STEL

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q05769-18-unknown ANPCCS... 18 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RSTEL 604 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)