Q06136: 3-ketodihydrosphingosine reductase

General Information

Protein names	- 3-ketodihydrosphingosine reductase - KDS reductase - 1.1.1.102 - 3-dehydrosphinganine reductase - Follicular variant translocation protein 1 - FVT-1 - Short chain dehydrogenase/reductase family 35C member 1
Gene names	KDSR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q06136

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MLLLAAAFLV AFVLLLYMVS PLISPKPLAL PGAHVVVTGG SSGIGKCIAI ECYKQGAFIT
        70         80         90        100        110        120
LVARNEDKLL QAKKEIEMHS INDKQVVLCI SVDVSQDYNQ VENVIKQAQE KLGPVDMLVN
       130        140        150        160        170        180
CAGMAVSGKF EDLEVSTFER LMSINYLGSV YPSRAVITTM KERRVGRIVF VSSQAGQLGL
       190        200        210        220        230        240
FGFTAYSASK FAIRGLAEAL QMEVKPYNVY ITVAYPPDTD TPGFAEENRT KPLETRLISE
       250        260        270        280        290        300
TTSVCKPEQV AKQIVKDAIQ GNFNSSLGSD GYMLSALTCG MAPVTSITEG LQQVVTMGLF
       310        320        330
RTIALFYLGS FDSIVRRCMM QREKSENADK TA

Isoforms

- Isoform 2 of 3-ketodihydrosphingosine reductase

Sequence View

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Evidence Codes:

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q06136-26-unknown	KPLALP...	26		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q06136-96-unknown	QDYNQV...	96		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000468203

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...VITTMK	160	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000467962
...ADKTA	332		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...ADKTA	332	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...ADKTA	332		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)