TopFIND 4.0

Q06164: E3 ubiquitin-protein ligase substrate receptor MMS22

General Information

Protein names
- E3 ubiquitin-protein ligase substrate receptor MMS22
- Methyl methanesulfonate-sensitivity protein 22
- Synthetically lethal with MCM10 protein 2
Gene names MMS22
Organism Saccharomyces cerevisiae
Protease Family
Protease ID
Chromosome location
UniProt ID Q06164

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDVDEPNPIV ISDSEATDEE ISIIYEPEFN ENYLWAEENV QEASRSQKIV TERLSLDSTA 
        70         80         90        100        110        120 
GESCTPSVVT DTQVTTGLRW SLRKRKAIQK MPYSLERIKH RQLLEGYDIS SFDSISNQLT 
       130        140        150        160        170        180 
LPKNASTVIH SNDILLTKRT GKPLDEQKDV TIDSIKPENS SVQSQRYDSD EEIPKKRHRT 
       190        200        210        220        230        240 
FKDLDQDIVF QSGDSTEDEQ DLASTNLQNT QNDEVIFRGR VLNVRTGYRG VLPRVAWEKS 
       250        260        270        280        290        300 
LQKQQSSKVT KRKTQLLNHK GVAKRKMNRS AHIEDEEQNL LNDLIAPDDE LDIEENAPPD 
       310        320        330        340        350        360 
IYLGNLPEDR EANEKELKEL QEYYESKYSE DAQSAGTSGF NLNEEYRNEP VYELEYDGPG 
       370        380        390        400        410        420 
SCISHVSYKD QPIIYLNSRH SDSGFSEQYN ISAEDNQSVI SLDAAEEHND GIIDKMLVKP 
       430        440        450        460        470        480 
KRIKATNDAN FLNTKSKRVR RYKYKYRNSC LAPSTKAIKV GKRSAHKSHL AANNPVSFVS 
       490        500        510        520        530        540 
KKNHVIDDYF FEELESQSLE QDDSSSLKPQ KKRRKKKAPI YSSFSADLES RRKPVFNTVV 
       550        560        570        580        590        600 
EVPTNRYAFT KPNVRNRDSI NHDMEFEEED SNQELGPIMV VLDSILLKKP FEPPNFFKIQ 
       610        620        630        640        650        660 
LSDKSFLLSK LNPADIATSL QKIFRVIIDK GITDTELVHF NESLIAFLVH LDMPELFDLI 
       670        680        690        700        710        720 
GEFHREFRSK VNSLRKKAKP IHFFQIAACQ LMFLEISRYN KISAAAKFDM DVKLLDHIVS 
       730        740        750        760        770        780 
FFKLLSVCYD SVMKNPMQYL YTSYYILSAV VDVIHKKEAL WDLFQKHPFS PHISLLLVNI 
       790        800        810        820        830        840 
FPTKVCRWQV LRLDSEFQPL SSAFRFINYC IETCNWNVTN SLILSLDRIF KRRRFSDFEE 
       850        860        870        880        890        900 
ESDLSQNNKI IYPPTNQLTS RLMFNRYLHL LTLCELSSSD TQRVIPMGDI SMNDSLSVLK 
       910        920        930        940        950        960 
NRLNLLIVLA TRFDLNLEKR FQELTRPLYS KEYLNLHTQN TVRTITTLIM QASLSFLEIS 
       970        980        990       1000       1010       1020 
RIKNHPFSGK FIASLFDKLV LQQPSISGVT ENFLKEFTNL VSKMKRKSVS MLKFLYPSLV 
      1030       1040       1050       1060       1070       1080 
AMSQENIFES SFFLLLQVYL KSLDVLGPTW VQNYLFQFIK SKAQENERWI ECYCQIGKFL 
      1090       1100       1110       1120       1130       1140 
VDSGIFTWWT FFTYNGLDAA LHFQLAFHSL IIDFCDTDSF ELLKKPLYSI ASDLLLISKD 
      1150       1160       1170       1180       1190       1200 
DAFYHFLSNL LKRAHIIVAD LKPVSDENEL LRLAYIFSKA LKKNAYQDLL AVFLSLAKKH 
      1210       1220       1230       1240       1250       1260 
YDEGDISRNF LAKYLEFLNK NCLTELRNNQ LFISLRRELG ISSDEDEKCA FWDSFNEAGD 
      1270       1280       1290       1300       1310       1320 
ILSKAAFVET GIVQACCTGN EIDGYLDNLS TLFTSTMLES PFAFFSDLVI AHIFENRPFF 
      1330       1340       1350       1360       1370       1380 
DVNIKNFLLS HFIDLFNKVL KMKFEQVSPD EFAELCKVYR ALCIECATDD TFNSNSDLIA 
      1390       1400       1410       1420       1430       1440 
AKDAFLVSVL RIADGFWEHD KLLQLRMLDS NMNIPNQIPH TTLQSSLSAI VIKIIESNIG 
      1450    
KIEASEPFKT FKNT

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q06164-1-unknown MDVDEP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TFKNT 1454 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)