Q06278: Aldehyde oxidase {ECO:0000312|HGNC:HGNC:553}

General Information

Protein names	- Aldehyde oxidase {ECO:0000312\|HGNC:HGNC:553} - 1.2.3.1 {ECO:0000269\|PubMed:22996261, ECO:0000269\|PubMed:26322824} - Aldehyde oxidase 1 - Azaheterocycle hydroxylase {ECO:0000305\|PubMed:7786031, ECO:0000305\|PubMed:9224775} - 1.17.3.- {ECO:0000269\|PubMed:7786031, ECO:0000269\|PubMed:9224775}
Gene names	AOX1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q06278

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDRASELLFY VNGRKVIEKN VDPETMLLPY LRKKLRLTGT KYGCGGGGCG ACTVMISRYN
        70         80         90        100        110        120
PITKRIRHHP ANACLIPICS LYGAAVTTVE GIGSTHTRIH PVQERIAKCH GTQCGFCTPG
       130        140        150        160        170        180
MVMSIYTLLR NHPEPTLDQL TDALGGNLCR CTGYRPIIDA CKTFCKTSGC CQSKENGVCC
       190        200        210        220        230        240
LDQGINGLPE FEEGSKTSPK LFAEEEFLPL DPTQELIFPP ELMIMAEKQS QRTRVFGSER
       250        260        270        280        290        300
MMWFSPVTLK ELLEFKFKYP QAPVIMGNTS VGPEVKFKGV FHPVIISPDR IEELSVVNHA
       310        320        330        340        350        360
YNGLTLGAGL SLAQVKDILA DVVQKLPEEK TQMYHALLKH LGTLAGSQIR NMASLGGHII
       370        380        390        400        410        420
SRHPDSDLNP ILAVGNCTLN LLSKEGKRQI PLNEQFLSKC PNADLKPQEI LVSVNIPYSR
       430        440        450        460        470        480
KWEFVSAFRQ AQRQENALAI VNSGMRVFFG EGDGIIRELC ISYGGVGPAT ICAKNSCQKL
       490        500        510        520        530        540
IGRHWNEQML DIACRLILNE VSLLGSAPGG KVEFKRTLII SFLFKFYLEV SQILKKMDPV
       550        560        570        580        590        600
HYPSLADKYE SALEDLHSKH HCSTLKYQNI GPKQHPEDPI GHPIMHLSGV KHATGEAIYC
       610        620        630        640        650        660
DDMPLVDQEL FLTFVTSSRA HAKIVSIDLS EALSMPGVVD IMTAEHLSDV NSFCFFTEAE
       670        680        690        700        710        720
KFLATDKVFC VGQLVCAVLA DSEVQAKRAA KRVKIVYQDL EPLILTIEES IQHNSSFKPE
       730        740        750        760        770        780
RKLEYGNVDE AFKVVDQILE GEIHMGGQEH FYMETQSMLV VPKGEDQEMD VYVSTQFPKY
       790        800        810        820        830        840
IQDIVASTLK LPANKVMCHV RRVGGAFGGK VLKTGIIAAV TAFAANKHGR AVRCVLERGE
       850        860        870        880        890        900
DMLITGGRHP YLGKYKAGFM NDGRILALDM EHYSNAGASL DESLFVIEMG LLKMDNAYKF
       910        920        930        940        950        960
PNLRCRGWAC RTNLPSNTAF RGFGFPQAAL ITESCITEVA AKCGLSPEKV RIINMYKEID
       970        980        990       1000       1010       1020
QTPYKQEINA KNLIQCWREC MAMSSYSLRK VAVEKFNAEN YWKKKGLAMV PLKFPVGLGS
      1030       1040       1050       1060       1070       1080
RAAGQAAALV HIYLDGSVLV THGGIEMGQG VHTKMIQVVS RELRMPMSNV HLRGTSTETV
      1090       1100       1110       1120       1130       1140
PNANISGGSV VADLNGLAVK DACQTLLKRL EPIISKNPKG TWKDWAQTAF DESINLSAVG
      1150       1160       1170       1180       1190       1200
YFRGYESDMN WEKGEGQPFE YFVYGAACSE VEIDCLTGDH KNIRTDIVMD VGCSINPAID
      1210       1220       1230       1240       1250       1260
IGQIEGAFIQ GMGLYTIEEL NYSPQGILHT RGPDQYKIPA ICDMPTELHI ALLPPSQNSN
      1270       1280       1290       1300       1310       1320
TLYSSKGLGE SGVFLGCSVF FAIHDAVSAA RQERGLHGPL TLNSPLTPEK IRMACEDKFT
      1330
KMIPRDEPGS YVPWNVPI

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q06278-1-unknown	MDRASE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q06278-26-unknown	MLLPYL...	26	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000392485
Q06278-1115-unknown	SKNPKG...	1115	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000260930
Q06278-1161-unknown	YFVYGA...	1161	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000413326

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QSKENG	176	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000392485
...RDEPGS	1329	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000260930
...WNVPI	1338	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)