Q06330: Recombining binding protein suppressor of hairless

General Information

Protein names	- Recombining binding protein suppressor of hairless - CBF-1 - J kappa-recombination signal-binding protein - RBP-J kappa - RBP-J - RBP-JK - Renal carcinoma antigen NY-REN-30
Gene names	RBPJ
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q06330

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform APCR-1 of Recombining binding protein suppressor of hairless - Isoform APCR-3 of Recombining binding protein suppressor of hairless - Isoform 4 of Recombining binding protein suppressor of hairless - Isoform 5 of Recombining binding protein suppressor of hairless - Isoform 6 of Recombining binding protein suppressor of hairless - Isoform 7 of Recombining binding protein suppressor of hairless

Sequence View

        10         20         30         40         50         60
MDHTEGSPAE EPPAHAPSPG KFGERPPPKR LTREAMRNYL KERGDQTVLI LHAKVAQKSY
        70         80         90        100        110        120
GNEKRFFCPP PCVYLMGSGW KKKKEQMERD GCSEQESQPC AFIGIGNSDQ EMQQLNLEGK
       130        140        150        160        170        180
NYCTAKTLYI SDSDKRKHFM LSVKMFYGNS DDIGVFLSKR IKVISKPSKK KQSLKNADLC
       190        200        210        220        230        240
IASGTKVALF NRLRSQTVST RYLHVEGGNF HASSQQWGAF FIHLLDDDES EGEEFTVRDG
       250        260        270        280        290        300
YIHYGQTVKL VCSVTGMALP RLIIRKVDKQ TALLDADDPV SQLHKCAFYL KDTERMYLCL
       310        320        330        340        350        360
SQERIIQFQA TPCPKEPNKE MINDGASWTI ISTDKAEYTF YEGMGPVLAP VTPVPVVESL
       370        380        390        400        410        420
QLNGGGDVAM LELTGQNFTP NLRVWFGDVE AETMYRCGES MLCVVPDISA FREGWRWVRQ
       430        440        450        460        470        480
PVQVPVTLVR NDGIIYSTSL TFTYTPEPGP RPHCSAAGAI LRANSSQVPP NESNTNSEGS
       490        500
YTNASTNSTS VTSSTATVVS         10         20         30         40         50         60
MDHTEGSPAE EPPAHAPSPG KFGERPPPKR LTREAMRNYL KERGDQTVLI LHAKVAQKSY
        70         80         90        100        110        120
GNEKRFFCPP PCVYLMGSGW KKKKEQMERD GCSEQESQPC AFIGIGNSDQ EMQQLNLEGK
       130        140        150        160        170        180
NYCTAKTLYI SDSDKRKHFM LSVKMFYGNS DDIGVFLSKR IKVISKPSKK KQSLKNADLC
       190        200        210        220        230        240
IASGTKVALF NRLRSQTVST RYLHVEGGNF HASSQQWGAF FIHLLDDDES EGEEFTVRDG
       250        260        270        280        290        300
YIHYGQTVKL VCSVTGMALP RLIIRKVDKQ TALLDADDPV SQLHKCAFYL KDTERMYLCL
       310        320        330        340        350        360
SQERIIQFQA TPCPKEPNKE MINDGASWTI ISTDKAEYTF YEGMGPVLAP VTPVPVVESL
       370        380        390        400        410        420
QLNGGGDVAM LELTGQNFTP NLRVWFGDVE AETMYRCGES MLCVVPDISA FREGWRWVRQ
       430        440        450        460        470        480
PVQVPVTLVR NDGIIYSTSL TFTYTPEPGP RPHCSAAGAI LRANSSQVPP NESNTNSEGS
       490        500
YTNASTNSTS VTSSTATVVS         10         20         30         40         50         60
MDHTEGSPAE EPPAHAPSPG KFGERPPPKR LTREAMRNYL KERGDQTVLI LHAKVAQKSY
        70         80         90        100        110        120
GNEKRFFCPP PCVYLMGSGW KKKKEQMERD GCSEQESQPC AFIGIGNSDQ EMQQLNLEGK
       130        140        150        160        170        180
NYCTAKTLYI SDSDKRKHFM LSVKMFYGNS DDIGVFLSKR IKVISKPSKK KQSLKNADLC
       190        200        210        220        230        240
IASGTKVALF NRLRSQTVST RYLHVEGGNF HASSQQWGAF FIHLLDDDES EGEEFTVRDG
       250        260        270        280        290        300
YIHYGQTVKL VCSVTGMALP RLIIRKVDKQ TALLDADDPV SQLHKCAFYL KDTERMYLCL
       310        320        330        340        350        360
SQERIIQFQA TPCPKEPNKE MINDGASWTI ISTDKAEYTF YEGMGPVLAP VTPVPVVESL
       370        380        390        400        410        420
QLNGGGDVAM LELTGQNFTP NLRVWFGDVE AETMYRCGES MLCVVPDISA FREGWRWVRQ
       430        440        450        460        470        480
PVQVPVTLVR NDGIIYSTSL TFTYTPEPGP RPHCSAAGAI LRANSSQVPP NESNTNSEGS
       490        500
YTNASTNSTS VTSSTATVVS         10         20         30         40         50         60
MDHTEGSPAE EPPAHAPSPG KFGERPPPKR LTREAMRNYL KERGDQTVLI LHAKVAQKSY
        70         80         90        100        110        120
GNEKRFFCPP PCVYLMGSGW KKKKEQMERD GCSEQESQPC AFIGIGNSDQ EMQQLNLEGK
       130        140        150        160        170        180
NYCTAKTLYI SDSDKRKHFM LSVKMFYGNS DDIGVFLSKR IKVISKPSKK KQSLKNADLC
       190        200        210        220        230        240
IASGTKVALF NRLRSQTVST RYLHVEGGNF HASSQQWGAF FIHLLDDDES EGEEFTVRDG
       250        260        270        280        290        300
YIHYGQTVKL VCSVTGMALP RLIIRKVDKQ TALLDADDPV SQLHKCAFYL KDTERMYLCL
       310        320        330        340        350        360
SQERIIQFQA TPCPKEPNKE MINDGASWTI ISTDKAEYTF YEGMGPVLAP VTPVPVVESL
       370        380        390        400        410        420
QLNGGGDVAM LELTGQNFTP NLRVWFGDVE AETMYRCGES MLCVVPDISA FREGWRWVRQ
       430        440        450        460        470        480
PVQVPVTLVR NDGIIYSTSL TFTYTPEPGP RPHCSAAGAI LRANSSQVPP NESNTNSEGS
       490        500
YTNASTNSTS VTSSTATVVS         10         20         30         40         50         60
MDHTEGSPAE EPPAHAPSPG KFGERPPPKR LTREAMRNYL KERGDQTVLI LHAKVAQKSY
        70         80         90        100        110        120
GNEKRFFCPP PCVYLMGSGW KKKKEQMERD GCSEQESQPC AFIGIGNSDQ EMQQLNLEGK
       130        140        150        160        170        180
NYCTAKTLYI SDSDKRKHFM LSVKMFYGNS DDIGVFLSKR IKVISKPSKK KQSLKNADLC
       190        200        210        220        230        240
IASGTKVALF NRLRSQTVST RYLHVEGGNF HASSQQWGAF FIHLLDDDES EGEEFTVRDG
       250        260        270        280        290        300
YIHYGQTVKL VCSVTGMALP RLIIRKVDKQ TALLDADDPV SQLHKCAFYL KDTERMYLCL
       310        320        330        340        350        360
SQERIIQFQA TPCPKEPNKE MINDGASWTI ISTDKAEYTF YEGMGPVLAP VTPVPVVESL
       370        380        390        400        410        420
QLNGGGDVAM LELTGQNFTP NLRVWFGDVE AETMYRCGES MLCVVPDISA FREGWRWVRQ
       430        440        450        460        470        480
PVQVPVTLVR NDGIIYSTSL TFTYTPEPGP RPHCSAAGAI LRANSSQVPP NESNTNSEGS
       490        500
YTNASTNSTS VTSSTATVVS         10         20         30         40         50         60
MDHTEGSPAE EPPAHAPSPG KFGERPPPKR LTREAMRNYL KERGDQTVLI LHAKVAQKSY
        70         80         90        100        110        120
GNEKRFFCPP PCVYLMGSGW KKKKEQMERD GCSEQESQPC AFIGIGNSDQ EMQQLNLEGK
       130        140        150        160        170        180
NYCTAKTLYI SDSDKRKHFM LSVKMFYGNS DDIGVFLSKR IKVISKPSKK KQSLKNADLC
       190        200        210        220        230        240
IASGTKVALF NRLRSQTVST RYLHVEGGNF HASSQQWGAF FIHLLDDDES EGEEFTVRDG
       250        260        270        280        290        300
YIHYGQTVKL VCSVTGMALP RLIIRKVDKQ TALLDADDPV SQLHKCAFYL KDTERMYLCL
       310        320        330        340        350        360
SQERIIQFQA TPCPKEPNKE MINDGASWTI ISTDKAEYTF YEGMGPVLAP VTPVPVVESL
       370        380        390        400        410        420
QLNGGGDVAM LELTGQNFTP NLRVWFGDVE AETMYRCGES MLCVVPDISA FREGWRWVRQ
       430        440        450        460        470        480
PVQVPVTLVR NDGIIYSTSL TFTYTPEPGP RPHCSAAGAI LRANSSQVPP NESNTNSEGS
       490        500
YTNASTNSTS VTSSTATVVS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q06330-1-unknown	MDHTEG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q06330-6-	GSPAEE...	6		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q06330-6-	GSPAEE...	6		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q06330-6-	GSPAEE...	6		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q06330-36-unknown	MRNYLK...	36	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91061
Q06330-36-unknown	MRNYLK...	36	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106037
Q06330-36-unknown	MRNYLK...	36	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106036
Q06330-36-unknown	MRNYLK...	36	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106035
Q06330-76-unknown	MGSGWK...	76	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt91058
Q06330-76-unknown	MGSGWK...	76	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt105850
Q06330-76-unknown	MGSGWK...	76	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt105851
Q06330-76-unknown	MGSGWK...	76	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt105849
Q06330-76-unknown	MGSGWK...	76	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt105848

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ATVVS	500	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ATVVS	500	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86677
...ATVVS	500	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86676
...ATVVS	500	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86679
...ATVVS	500	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86678
...ATVVS	500	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86680
...ATVVS	500	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86681

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)