TopFIND 4.0

Q07731: Glial cell line-derived neurotrophic factor

General Information

Protein names
- Glial cell line-derived neurotrophic factor
- Astrocyte-derived trophic factor
- ATF
Gene names Gdnf
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q07731

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKLWDVVAVC LVLLHTASAF PLPAGKRLLE APAEDHSLGH RRVPFALTSD SNMPEDYPDQ 
        70         80         90        100        110        120 
FDDVMDFIQA TIKRLKRSPD KQAAALPRRE RNRQAAAASP ENSRGKGRRG QRGKNRGCVL 
       130        140        150        160        170        180 
TAIHLNVTDL GLGYETKEEL IFRYCSGSCE AAETMYDKIL KNLSRSRRLT SDKVGQACCR 
       190        200        210    
PVAFDDDLSF LDDSLVYHIL RKHSAKRCGC I

Isoforms

- Isoform 2 of Glial cell line-derived neurotrophic factor - Isoform 3 of Glial cell line-derived neurotrophic factor - Isoform 4 of Glial cell line-derived neurotrophic factor

Sequence View

        10         20         30         40         50         60 
MKLWDVVAVC LVLLHTASAF PLPAGKRLLE APAEDHSLGH RRVPFALTSD SNMPEDYPDQ 
        70         80         90        100        110        120 
FDDVMDFIQA TIKRLKRSPD KQAAALPRRE RNRQAAAASP ENSRGKGRRG QRGKNRGCVL 
       130        140        150        160        170        180 
TAIHLNVTDL GLGYETKEEL IFRYCSGSCE AAETMYDKIL KNLSRSRRLT SDKVGQACCR 
       190        200        210    
PVAFDDDLSF LDDSLVYHIL RKHSAKRCGC I         10         20         30         40         50         60 
MKLWDVVAVC LVLLHTASAF PLPAGKRLLE APAEDHSLGH RRVPFALTSD SNMPEDYPDQ 
        70         80         90        100        110        120 
FDDVMDFIQA TIKRLKRSPD KQAAALPRRE RNRQAAAASP ENSRGKGRRG QRGKNRGCVL 
       130        140        150        160        170        180 
TAIHLNVTDL GLGYETKEEL IFRYCSGSCE AAETMYDKIL KNLSRSRRLT SDKVGQACCR 
       190        200        210    
PVAFDDDLSF LDDSLVYHIL RKHSAKRCGC I         10         20         30         40         50         60 
MKLWDVVAVC LVLLHTASAF PLPAGKRLLE APAEDHSLGH RRVPFALTSD SNMPEDYPDQ 
        70         80         90        100        110        120 
FDDVMDFIQA TIKRLKRSPD KQAAALPRRE RNRQAAAASP ENSRGKGRRG QRGKNRGCVL 
       130        140        150        160        170        180 
TAIHLNVTDL GLGYETKEEL IFRYCSGSCE AAETMYDKIL KNLSRSRRLT SDKVGQACCR 
       190        200        210    
PVAFDDDLSF LDDSLVYHIL RKHSAKRCGC I



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)