TopFIND 4.0

Q08117: TLE family member 5 {ECO:0000305}

General Information

Protein names
- TLE family member 5 {ECO:0000305}
- Amino-terminal enhancer of split
- Amino enhancer of split
- Gp130-associated protein GAM
- Grg-5
- Groucho-related protein 5
- Protein ESP1
- Protein GRG
- TLE family member 5, transcriptional modulator {ECO:0000305}
Gene names AES
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q08117

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MMFPQSRHSG SSHLPQQLKF TTSDSCDRIK DEFQLLQAQY HSLKLECDKL ASEKSEMQRH 
        70         80         90        100        110        120 
YVMYYEMSYG LNIEMHKQAE IVKRLNGICA QVLPYLSQEH QQQVLGAIER AKQVTAPELN 
       130        140        150        160        170        180 
SIIRQQLQAH QLSQLQALAL PLTPLPVGLQ PPSLPAVSAG TGLLSLSALG SQAHLSKEDK 
       190    
NGHDGDTHQE DDGEKSD

Isoforms

- Isoform 2 of Amino-terminal enhancer of split - Isoform 2 of TLE family member 5

Sequence View

        10         20         30         40         50         60 
MMFPQSRHSG SSHLPQQLKF TTSDSCDRIK DEFQLLQAQY HSLKLECDKL ASEKSEMQRH 
        70         80         90        100        110        120 
YVMYYEMSYG LNIEMHKQAE IVKRLNGICA QVLPYLSQEH QQQVLGAIER AKQVTAPELN 
       130        140        150        160        170        180 
SIIRQQLQAH QLSQLQALAL PLTPLPVGLQ PPSLPAVSAG TGLLSLSALG SQAHLSKEDK 
       190    
NGHDGDTHQE DDGEKSD         10         20         30         40         50         60 
MMFPQSRHSG SSHLPQQLKF TTSDSCDRIK DEFQLLQAQY HSLKLECDKL ASEKSEMQRH 
        70         80         90        100        110        120 
YVMYYEMSYG LNIEMHKQAE IVKRLNGICA QVLPYLSQEH QQQVLGAIER AKQVTAPELN 
       130        140        150        160        170        180 
SIIRQQLQAH QLSQLQALAL PLTPLPVGLQ PPSLPAVSAG TGLLSLSALG SQAHLSKEDK 
       190    
NGHDGDTHQE DDGEKSD



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Evidence Codes:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q08117-1-unknown MMFPQS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q08117-2-unknown MFPQSR... 2 inferred from electronic annotation unknown TISdb inferred from TISdb

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GEKSD 197 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...GEKSD 197 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt62061

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)