TopFIND 4.0

Q08501: Prolactin receptor

General Information

Protein names
- Prolactin receptor
- PRL-R
Gene names Prlr
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q08501

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSSALAYMLL VLSISLLNGQ SPPGKPEIHK CRSPDKETFT CWWNPGSDGG LPTNYSLTYS 
        70         80         90        100        110        120 
KEGEKNTYEC PDYKTSGPNS CFFSKQYTSI WKIYIITVNA TNEMGSSTSD PLYVDVTYIV 
       130        140        150        160        170        180 
EPEPPRNLTL EVKQLKDKKT YLWVKWLPPT ITDVKTGWFT MEYEIRLKSE EADEWEIHFT 
       190        200        210        220        230        240 
GHQTQFKVFD LYPGQKYLVQ TRCKPDHGYW SRWGQEKSIE IPNDFTLKDT TVWIIVAVLS 
       250        260        270        280        290        300 
AVICLIMVWA VALKGYSMMT CIFPPVPGPK IKGFDTHLLE KGKSEELLSA LGCQDFPPTS 
       310        320        330        340        350        360 
DCEDLLVEFL EVDDNEDERL MPSHSKEYPG QGVKPTHLDP DSDSGHGSYD SHSLLSEKCE 
       370        380        390        400        410        420 
EPQAYPPAFH IPEITEKPEN PEANIPPTPN PQNNTPNCHT DTSKSTTWPL PPGQHTRRSP 
       430        440        450        460        470        480 
YHSIADVCKL AGSPGDTLDS FLDKAEENVL KLSEDAGEEE VAVQEGAKSF PSDKQNTSWP 
       490        500        510        520        530        540 
PLQEKGPIVY AKPPDYVEIH KVNKDGVLSL LPKQRENHQT ENPGVPETSK EYAKVSGVTD 
       550        560        570        580        590        600 
NNILVLVPDS RAQNTALLEE SAKKVPPSLE QNQSEKDLAS FTATSSNCRL QLGRLDYLDP 
   
TCFMHSFH

Isoforms

- Isoform PRL-R1 of Prolactin receptor - Isoform PRL-R2 of Prolactin receptor

Sequence View

        10         20         30         40         50         60 
MSSALAYMLL VLSISLLNGQ SPPGKPEIHK CRSPDKETFT CWWNPGSDGG LPTNYSLTYS 
        70         80         90        100        110        120 
KEGEKNTYEC PDYKTSGPNS CFFSKQYTSI WKIYIITVNA TNEMGSSTSD PLYVDVTYIV 
       130        140        150        160        170        180 
EPEPPRNLTL EVKQLKDKKT YLWVKWLPPT ITDVKTGWFT MEYEIRLKSE EADEWEIHFT 
       190        200        210        220        230        240 
GHQTQFKVFD LYPGQKYLVQ TRCKPDHGYW SRWGQEKSIE IPNDFTLKDT TVWIIVAVLS 
       250        260        270        280        290        300 
AVICLIMVWA VALKGYSMMT CIFPPVPGPK IKGFDTHLLE KGKSEELLSA LGCQDFPPTS 
       310        320        330        340        350        360 
DCEDLLVEFL EVDDNEDERL MPSHSKEYPG QGVKPTHLDP DSDSGHGSYD SHSLLSEKCE 
       370        380        390        400        410        420 
EPQAYPPAFH IPEITEKPEN PEANIPPTPN PQNNTPNCHT DTSKSTTWPL PPGQHTRRSP 
       430        440        450        460        470        480 
YHSIADVCKL AGSPGDTLDS FLDKAEENVL KLSEDAGEEE VAVQEGAKSF PSDKQNTSWP 
       490        500        510        520        530        540 
PLQEKGPIVY AKPPDYVEIH KVNKDGVLSL LPKQRENHQT ENPGVPETSK EYAKVSGVTD 
       550        560        570        580        590        600 
NNILVLVPDS RAQNTALLEE SAKKVPPSLE QNQSEKDLAS FTATSSNCRL QLGRLDYLDP 
   
TCFMHSFH         10         20         30         40         50         60 
MSSALAYMLL VLSISLLNGQ SPPGKPEIHK CRSPDKETFT CWWNPGSDGG LPTNYSLTYS 
        70         80         90        100        110        120 
KEGEKNTYEC PDYKTSGPNS CFFSKQYTSI WKIYIITVNA TNEMGSSTSD PLYVDVTYIV 
       130        140        150        160        170        180 
EPEPPRNLTL EVKQLKDKKT YLWVKWLPPT ITDVKTGWFT MEYEIRLKSE EADEWEIHFT 
       190        200        210        220        230        240 
GHQTQFKVFD LYPGQKYLVQ TRCKPDHGYW SRWGQEKSIE IPNDFTLKDT TVWIIVAVLS 
       250        260        270        280        290        300 
AVICLIMVWA VALKGYSMMT CIFPPVPGPK IKGFDTHLLE KGKSEELLSA LGCQDFPPTS 
       310        320        330        340        350        360 
DCEDLLVEFL EVDDNEDERL MPSHSKEYPG QGVKPTHLDP DSDSGHGSYD SHSLLSEKCE 
       370        380        390        400        410        420 
EPQAYPPAFH IPEITEKPEN PEANIPPTPN PQNNTPNCHT DTSKSTTWPL PPGQHTRRSP 
       430        440        450        460        470        480 
YHSIADVCKL AGSPGDTLDS FLDKAEENVL KLSEDAGEEE VAVQEGAKSF PSDKQNTSWP 
       490        500        510        520        530        540 
PLQEKGPIVY AKPPDYVEIH KVNKDGVLSL LPKQRENHQT ENPGVPETSK EYAKVSGVTD 
       550        560        570        580        590        600 
NNILVLVPDS RAQNTALLEE SAKKVPPSLE QNQSEKDLAS FTATSSNCRL QLGRLDYLDP 
   
TCFMHSFH



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...MHSFH 608 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)