Q08509: Epidermal growth factor receptor kinase substrate 8

General Information

Protein names	- Epidermal growth factor receptor kinase substrate 8
Gene names	Eps8
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q08509

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNGHMSNRSS GYGVYPSQLN GYGSSPPYSQ MDREHSSRTS AKALYEQRKN YARDSVSSVS
        70         80         90        100        110        120
DVSQYRVEHL TTFVLDRKDA MITVEDGIRK LKLLDAKGKV WTQDMILQVD DRAVSLIDLE
       130        140        150        160        170        180
SKNELENFPL NTISHCQAVV HACSYDSILA LVCKEPTQSK PDLHLFQCDE VKANLISEDI
       190        200        210        220        230        240
ESAISDSKGG KQKRRPEALR MIAKADPGIP PPPRAPAPVP PGTVTQVDVR SRVAAWSAWA
       250        260        270        280        290        300
ADQGDFEKPR QYHEQEETPE MMAARIDRDV QILNHILDDI EFFITKLQKA AEAFSELSKR
       310        320        330        340        350        360
KKSKKSKRKG PGEGVLTLRA KPPPPDEFVD CFQKFKHGFN LLAKLKSHIQ NPSASDLVHF
       370        380        390        400        410        420
LFTPLNMVVQ ATGGPELASS VLSPLLTKDT VDFLNYTATA EERKLWMSLG DSWVKVRAEW
       430        440        450        460        470        480
PKEQFIPPYV PRFRNGWEPP MLNFMGAPTE QDMYQLAESV ANAEHQRKQD SKRLSTEHSN
       490        500        510        520        530        540
VSDYPPADGY AYSSSMYHRG PHADHGEAAM PFKSTPNHQV DRNYDAVKTQ PKKYAKSKYD
       550        560        570        580        590        600
FVARNSSELS VMKDDVLEIL DDRRQWWKVR NASGDSGFVP NNILDIMRTP ESGVGRADPP
       610        620        630        640        650        660
YTHTIQKQRT EYGLRSADTP SAPSPPPTPA PVPVPLPPSV PAPVSVPKVP ANVTRQNSSS
       670        680        690        700        710        720
SDSGGSIVRD SQRYKQLPVD RRKSQMEEVQ DELFQRLTIG RSAAQRKFHV PRQNVPVINI
       730        740        750        760        770        780
TYDSSPEEVK TWLQSKGFNP VTVNSLGVLN GAQLFSLNKD ELRSVCPEGA RVFNQITVQK
       790        800        810        820
AALEDSNGSS ELQEIMRRRQ EKISAAASDS GVESFDEGSS H

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q08509-1-unknown	MNGHMS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q08509-262-unknown	MAARID...	262		inferred from electronic annotation	unknown	TISdb		inferred from TISdb

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SDSKGG	189	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119997
...RKGPGE	312	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122517
...ILDIMR	587	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120044
...EGSSH	821	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)