TopFIND 4.0

Q08AF3: Schlafen family member 5

General Information

Protein names
- Schlafen family member 5
Gene names SLFN5
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q08AF3

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSLRIDVDTN FPECVVDAGK VTLGTQQRQE MDPRLREKQN EIILRAVCAL LNSGGGIIKA 
        70         80         90        100        110        120 
EIENKGYNYE RHGVGLDVPP IFRSHLDKMQ KENHFLIFVK SWNTEAGVPL ATLCSNLYHR 
       130        140        150        160        170        180 
ERTSTDVMDS QEALAFLKCR TQTPTNINVS NSLGPQAAQG SVQYEGNINV SAAALFDRKR 
       190        200        210        220        230        240 
LQYLEKLNLP ESTHVEFVMF STDVSHCVKD RLPKCVSAFA NTEGGYVFFG VHDETCQVIG 
       250        260        270        280        290        300 
CEKEKIDLTS LRASIDGCIK KLPVHHFCTQ RPEIKYVLNF LEVHDKGALR GYVCAIKVEK 
       310        320        330        340        350        360 
FCCAVFAKVP SSWQVKDNRV RQLPTREWTA WMMEADPDLS RCPEMVLQLS LSSATPRSKP 
       370        380        390        400        410        420 
VCIHKNSECL KEQQKRYFPV FSDRVVYTPE SLYKELFSQH KGLRDLINTE MRPFSQGILI 
       430        440        450        460        470        480 
FSQSWAVDLG LQEKQGVICD ALLISQNNTP ILYTIFSKWD AGCKGYSMIV AYSLKQKLVN 
       490        500        510        520        530        540 
KGGYTGRLCI TPLVCVLNSD RKAQSVYSSY LQIYPESYNF MTPQHMEALL QSLVIVLLGF 
       550        560        570        580        590        600 
KSFLSEELGS EVLNLLTNKQ YELLSKNLRK TRELFVHGLP GSGKTILALR IMEKIRNVFH 
       610        620        630        640        650        660 
CEPANILYIC ENQPLKKLVS FSKKNICQPV TRKTFMKNNF EHIQHIIIDD AQNFRTEDGD 
       670        680        690        700        710        720 
WYGKAKFITQ TARDGPGVLW IFLDYFQTYH LSCSGLPPPS DQYPREEINR VVRNAGPIAN 
       730        740        750        760        770        780 
YLQQVMQEAR QNPPPNLPPG SLVMLYEPKW AQGVPGNLEI IEDLNLEEIL IYVANKCRFL 
       790        800        810        820        830        840 
LRNGYSPKDI AVLFTKASEV EKYKDRLLTA MRKRKLSQLH EESDLLLQIG DASDVLTDHI 
       850        860        870        880        890    
VLDSVCRFSG LERNIVFGIN PGVAPPAGAY NLLLCLASRA KRHLYILKAS V

Isoforms

- Isoform 2 of Schlafen family member 5

Sequence View

        10         20         30         40         50         60 
MSLRIDVDTN FPECVVDAGK VTLGTQQRQE MDPRLREKQN EIILRAVCAL LNSGGGIIKA 
        70         80         90        100        110        120 
EIENKGYNYE RHGVGLDVPP IFRSHLDKMQ KENHFLIFVK SWNTEAGVPL ATLCSNLYHR 
       130        140        150        160        170        180 
ERTSTDVMDS QEALAFLKCR TQTPTNINVS NSLGPQAAQG SVQYEGNINV SAAALFDRKR 
       190        200        210        220        230        240 
LQYLEKLNLP ESTHVEFVMF STDVSHCVKD RLPKCVSAFA NTEGGYVFFG VHDETCQVIG 
       250        260        270        280        290        300 
CEKEKIDLTS LRASIDGCIK KLPVHHFCTQ RPEIKYVLNF LEVHDKGALR GYVCAIKVEK 
       310        320        330        340        350        360 
FCCAVFAKVP SSWQVKDNRV RQLPTREWTA WMMEADPDLS RCPEMVLQLS LSSATPRSKP 
       370        380        390        400        410        420 
VCIHKNSECL KEQQKRYFPV FSDRVVYTPE SLYKELFSQH KGLRDLINTE MRPFSQGILI 
       430        440        450        460        470        480 
FSQSWAVDLG LQEKQGVICD ALLISQNNTP ILYTIFSKWD AGCKGYSMIV AYSLKQKLVN 
       490        500        510        520        530        540 
KGGYTGRLCI TPLVCVLNSD RKAQSVYSSY LQIYPESYNF MTPQHMEALL QSLVIVLLGF 
       550        560        570        580        590        600 
KSFLSEELGS EVLNLLTNKQ YELLSKNLRK TRELFVHGLP GSGKTILALR IMEKIRNVFH 
       610        620        630        640        650        660 
CEPANILYIC ENQPLKKLVS FSKKNICQPV TRKTFMKNNF EHIQHIIIDD AQNFRTEDGD 
       670        680        690        700        710        720 
WYGKAKFITQ TARDGPGVLW IFLDYFQTYH LSCSGLPPPS DQYPREEINR VVRNAGPIAN 
       730        740        750        760        770        780 
YLQQVMQEAR QNPPPNLPPG SLVMLYEPKW AQGVPGNLEI IEDLNLEEIL IYVANKCRFL 
       790        800        810        820        830        840 
LRNGYSPKDI AVLFTKASEV EKYKDRLLTA MRKRKLSQLH EESDLLLQIG DASDVLTDHI 
       850        860        870        880        890    
VLDSVCRFSG LERNIVFGIN PGVAPPAGAY NLLLCLASRA KRHLYILKAS V



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)