TopFIND 4.0

Q08AH1: Acyl-coenzyme A synthetase ACSM1, mitochondrial

General Information

Protein names
- Acyl-coenzyme A synthetase ACSM1, mitochondrial
- 6.2.1.2
- Acyl-CoA synthetase medium-chain family member 1
- Butyrate--CoA ligase 1
- Butyryl-coenzyme A synthetase 1
- Lipoate-activating enzyme
- Middle-chain acyl-CoA synthetase 1
Gene names ACSM1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q08AH1

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MQWLMRFRTL WGIHKSFHNI HPAPSQLRCR SLSEFGAPRW NDYEVPEEFN FASYVLDYWA 
        70         80         90        100        110        120 
QKEKEGKRGP NPAFWWVNGQ GDEVKWSFRE MGDLTRRVAN VFTQTCGLQQ GDHLALMLPR 
       130        140        150        160        170        180 
VPEWWLVAVG CMRTGIIFIP ATILLKAKDI LYRLQLSKAK GIVTIDALAS EVDSIASQCP 
       190        200        210        220        230        240 
SLKTKLLVSD HSREGWLDFR SLVKSASPEH TCVKSKTLDP MVIFFTSGTT GFPKMAKHSH 
       250        260        270        280        290        300 
GLALQPSFPG SRKLRSLKTS DVSWCLSDSG WIVATIWTLV EPWTAGCTVF IHHLPQFDTK 
       310        320        330        340        350        360 
VIIQTLLKYP INHFWGVSSI YRMILQQDFT SIRFPALEHC YTGGEVVLPK DQEEWKRRTG 
       370        380        390        400        410        420 
LLLYENYGQS ETGLICATYW GMKIKPGFMG KATPPYDVQV IDDKGSILPP NTEGNIGIRI 
       430        440        450        460        470        480 
KPVRPVSLFM CYEGDPEKTA KVECGDFYNT GDRGKMDEEG YICFLGRSDD IINASGYRIG 
       490        500        510        520        530        540 
PAEVESALVE HPAVAESAVV GSPDPIRGEV VKAFIVLTPQ FLSHDKDQLT KELQQHVKSV 
       550        560        570    
TAPYKYPRKV EFVSELPKTI TGKIERKELR KKETGQM

Isoforms

- Isoform 2 of Acyl-coenzyme A synthetase ACSM1, mitochondrial

Sequence View

        10         20         30         40         50         60 
MQWLMRFRTL WGIHKSFHNI HPAPSQLRCR SLSEFGAPRW NDYEVPEEFN FASYVLDYWA 
        70         80         90        100        110        120 
QKEKEGKRGP NPAFWWVNGQ GDEVKWSFRE MGDLTRRVAN VFTQTCGLQQ GDHLALMLPR 
       130        140        150        160        170        180 
VPEWWLVAVG CMRTGIIFIP ATILLKAKDI LYRLQLSKAK GIVTIDALAS EVDSIASQCP 
       190        200        210        220        230        240 
SLKTKLLVSD HSREGWLDFR SLVKSASPEH TCVKSKTLDP MVIFFTSGTT GFPKMAKHSH 
       250        260        270        280        290        300 
GLALQPSFPG SRKLRSLKTS DVSWCLSDSG WIVATIWTLV EPWTAGCTVF IHHLPQFDTK 
       310        320        330        340        350        360 
VIIQTLLKYP INHFWGVSSI YRMILQQDFT SIRFPALEHC YTGGEVVLPK DQEEWKRRTG 
       370        380        390        400        410        420 
LLLYENYGQS ETGLICATYW GMKIKPGFMG KATPPYDVQV IDDKGSILPP NTEGNIGIRI 
       430        440        450        460        470        480 
KPVRPVSLFM CYEGDPEKTA KVECGDFYNT GDRGKMDEEG YICFLGRSDD IINASGYRIG 
       490        500        510        520        530        540 
PAEVESALVE HPAVAESAVV GSPDPIRGEV VKAFIVLTPQ FLSHDKDQLT KELQQHVKSV 
       550        560        570    
TAPYKYPRKV EFVSELPKTI TGKIERKELR KKETGQM



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RSLVKS 204 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61837
    ...ETGQM 577 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)