TopFIND 4.0

Q0P5W1: Vacuolar protein sorting-associated protein 8 homolog

General Information

Protein names
- Vacuolar protein sorting-associated protein 8 homolog
Gene names Vps8
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q0P5W1

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
METEPDQEHL DQNPCARTVE EELSKSFNLE ASLSKFSCLD LDKELEFRSD LIDDKEFDIP 
        70         80         90        100        110        120 
QVDTPPTLES ILNETDDEDE SFVLEDPTLL NVDTIDSHSY DTSSVASSDS GDRANLKRKK 
       130        140        150        160        170        180 
KLPDSFSLHG SVMRHSLLKG ISAQIVSAAD KVDAGLPTAI AVSSLIAVGT SHGLALIFDQ 
       190        200        210        220        230        240 
NQALRLCLGS TSVGGQYGAI SALSINNDCS RLLCGFAKGQ ITMWDLASGK LLRSITDAHP 
       250        260        270        280        290        300 
PGTAILHIKF TDDPTLAICN DSGGSVFELT FKRVMGVRTC ESRCLFSGSK GEVCCIEPLH 
       310        320        330        340        350        360 
SKPELKDHPI TQFSLLAMAS LTKILVIGLK PSLKVWMTFP YGRMDPSSVP LLAWHFVAVN 
       370        380        390        400        410        420 
NSVNPMLAFC RGDMVHFLLV KRDESGAIHV TKQKHLHLYY DLINFTWINS RTVVLLDSVE 
       430        440        450        460        470        480 
KLHVIDRQTQ EELETMEISE VQLVYNSSHF KSLATGGNVS QALALVGEKA CYQSISSYGG 
       490        500        510        520        530        540 
QIFYLGTKSV YVMMLRSWRE RMDHLLKQDC LTEALALAWS FHEGKAKAVV GLSGDVSKRK 
       550        560        570        580        590        600 
AVVADRMVEI LFHYADRALK KCPDQGKIQV MEQHFQDTVP VIVDYCLLLQ RKDLLFGQMY 
       610        620        630        640        650        660 
DKLSENSVAK GVFLECLEPY ILSDKLVGIT PQVMKDLIVH FQDKKLLENV EALIVHMDIT 
       670        680        690        700        710        720 
SLDIQQVVLM CWENRLYDAM VYVYNRGMNE FISPMEKLFK VIAPPLNAGK TLTDEQVVMG 
       730        740        750        760        770        780 
NKLLVYISCC LAGRAYPLGD IPEDLVPLVK NQVFEFLIRL HSVEASSEEE VYPYVRTLLH 
       790        800        810        820        830        840 
FDTREFLNVL ALTFEDFKND KQAVEYQQRI VDILLKVMVE NSDFTPSQVG CLFTFLARQL 
       850        860        870        880        890        900 
AKPDNTLFVN RTLFDQVLEF LCSPDDDSRH SERQQVLLEL LQAGGIVQFE ESRLIRMAEK 
       910        920        930        940        950        960 
AEFYQICEFM YEREHQYDKI IDCYLHDPLR EEEVFNYIHN ILSIPGHSAE EKQSVWQKAM 
       970        980        990       1000       1010       1020 
NHMEELVSLK PCKAAELVAT HFSEQIEVVI GQLQNQLLLF KFLRSLLDPR EGVHVNQELL 
      1030       1040       1050       1060       1070       1080 
QIPPHITEQF IELLCQFSPD QVIQTLQVLE CYRLEETIQI TQKYQLHEVT AYLLEKKGDA 
      1090       1100       1110       1120       1130       1140 
HGAFLLLLER LQSRLQEMTR QDENTKEDIL LKGVEDTMVE TIALCQRNSQ NLNQQQREAL 
      1150       1160       1170       1180       1190       1200 
WFPLLEAMMT PQKLSSSAAA PHPHCEALKS LTMQVLNSMA AFIALPSILQ RILQDPIYGK 
      1210       1220       1230       1240       1250       1260 
GKLGEIQGLI LGMLDTFNYE QTLLETTASL LNQDLHWSLC NLRASVSRGL NPKQDYCSIC 
      1270       1280       1290       1300       1310       1320 
LQQYKRRQEM ADEIIVFSCG HLYHSFCLQS KECTLEVEGQ TRWACHKCSS SNKAGKLSEN 
      1330       1340       1350       1360       1370       1380 
PSENKKGRIT SSQVKMSPSY HQSKGDPPAR KANSEPVLDP QQMQAFDQLC RLYRGSSRLA 
      1390       1400       1410       1420    
LLTELSQNRG GDSCRPFAGP QSGPAFNSVF QKENFQLQLA PPPVAED

Isoforms

- Isoform 2 of Vacuolar protein sorting-associated protein 8 homolog - Isoform 3 of Vacuolar protein sorting-associated protein 8 homolog

Sequence View

        10         20         30         40         50         60 
METEPDQEHL DQNPCARTVE EELSKSFNLE ASLSKFSCLD LDKELEFRSD LIDDKEFDIP 
        70         80         90        100        110        120 
QVDTPPTLES ILNETDDEDE SFVLEDPTLL NVDTIDSHSY DTSSVASSDS GDRANLKRKK 
       130        140        150        160        170        180 
KLPDSFSLHG SVMRHSLLKG ISAQIVSAAD KVDAGLPTAI AVSSLIAVGT SHGLALIFDQ 
       190        200        210        220        230        240 
NQALRLCLGS TSVGGQYGAI SALSINNDCS RLLCGFAKGQ ITMWDLASGK LLRSITDAHP 
       250        260        270        280        290        300 
PGTAILHIKF TDDPTLAICN DSGGSVFELT FKRVMGVRTC ESRCLFSGSK GEVCCIEPLH 
       310        320        330        340        350        360 
SKPELKDHPI TQFSLLAMAS LTKILVIGLK PSLKVWMTFP YGRMDPSSVP LLAWHFVAVN 
       370        380        390        400        410        420 
NSVNPMLAFC RGDMVHFLLV KRDESGAIHV TKQKHLHLYY DLINFTWINS RTVVLLDSVE 
       430        440        450        460        470        480 
KLHVIDRQTQ EELETMEISE VQLVYNSSHF KSLATGGNVS QALALVGEKA CYQSISSYGG 
       490        500        510        520        530        540 
QIFYLGTKSV YVMMLRSWRE RMDHLLKQDC LTEALALAWS FHEGKAKAVV GLSGDVSKRK 
       550        560        570        580        590        600 
AVVADRMVEI LFHYADRALK KCPDQGKIQV MEQHFQDTVP VIVDYCLLLQ RKDLLFGQMY 
       610        620        630        640        650        660 
DKLSENSVAK GVFLECLEPY ILSDKLVGIT PQVMKDLIVH FQDKKLLENV EALIVHMDIT 
       670        680        690        700        710        720 
SLDIQQVVLM CWENRLYDAM VYVYNRGMNE FISPMEKLFK VIAPPLNAGK TLTDEQVVMG 
       730        740        750        760        770        780 
NKLLVYISCC LAGRAYPLGD IPEDLVPLVK NQVFEFLIRL HSVEASSEEE VYPYVRTLLH 
       790        800        810        820        830        840 
FDTREFLNVL ALTFEDFKND KQAVEYQQRI VDILLKVMVE NSDFTPSQVG CLFTFLARQL 
       850        860        870        880        890        900 
AKPDNTLFVN RTLFDQVLEF LCSPDDDSRH SERQQVLLEL LQAGGIVQFE ESRLIRMAEK 
       910        920        930        940        950        960 
AEFYQICEFM YEREHQYDKI IDCYLHDPLR EEEVFNYIHN ILSIPGHSAE EKQSVWQKAM 
       970        980        990       1000       1010       1020 
NHMEELVSLK PCKAAELVAT HFSEQIEVVI GQLQNQLLLF KFLRSLLDPR EGVHVNQELL 
      1030       1040       1050       1060       1070       1080 
QIPPHITEQF IELLCQFSPD QVIQTLQVLE CYRLEETIQI TQKYQLHEVT AYLLEKKGDA 
      1090       1100       1110       1120       1130       1140 
HGAFLLLLER LQSRLQEMTR QDENTKEDIL LKGVEDTMVE TIALCQRNSQ NLNQQQREAL 
      1150       1160       1170       1180       1190       1200 
WFPLLEAMMT PQKLSSSAAA PHPHCEALKS LTMQVLNSMA AFIALPSILQ RILQDPIYGK 
      1210       1220       1230       1240       1250       1260 
GKLGEIQGLI LGMLDTFNYE QTLLETTASL LNQDLHWSLC NLRASVSRGL NPKQDYCSIC 
      1270       1280       1290       1300       1310       1320 
LQQYKRRQEM ADEIIVFSCG HLYHSFCLQS KECTLEVEGQ TRWACHKCSS SNKAGKLSEN 
      1330       1340       1350       1360       1370       1380 
PSENKKGRIT SSQVKMSPSY HQSKGDPPAR KANSEPVLDP QQMQAFDQLC RLYRGSSRLA 
      1390       1400       1410       1420    
LLTELSQNRG GDSCRPFAGP QSGPAFNSVF QKENFQLQLA PPPVAED         10         20         30         40         50         60 
METEPDQEHL DQNPCARTVE EELSKSFNLE ASLSKFSCLD LDKELEFRSD LIDDKEFDIP 
        70         80         90        100        110        120 
QVDTPPTLES ILNETDDEDE SFVLEDPTLL NVDTIDSHSY DTSSVASSDS GDRANLKRKK 
       130        140        150        160        170        180 
KLPDSFSLHG SVMRHSLLKG ISAQIVSAAD KVDAGLPTAI AVSSLIAVGT SHGLALIFDQ 
       190        200        210        220        230        240 
NQALRLCLGS TSVGGQYGAI SALSINNDCS RLLCGFAKGQ ITMWDLASGK LLRSITDAHP 
       250        260        270        280        290        300 
PGTAILHIKF TDDPTLAICN DSGGSVFELT FKRVMGVRTC ESRCLFSGSK GEVCCIEPLH 
       310        320        330        340        350        360 
SKPELKDHPI TQFSLLAMAS LTKILVIGLK PSLKVWMTFP YGRMDPSSVP LLAWHFVAVN 
       370        380        390        400        410        420 
NSVNPMLAFC RGDMVHFLLV KRDESGAIHV TKQKHLHLYY DLINFTWINS RTVVLLDSVE 
       430        440        450        460        470        480 
KLHVIDRQTQ EELETMEISE VQLVYNSSHF KSLATGGNVS QALALVGEKA CYQSISSYGG 
       490        500        510        520        530        540 
QIFYLGTKSV YVMMLRSWRE RMDHLLKQDC LTEALALAWS FHEGKAKAVV GLSGDVSKRK 
       550        560        570        580        590        600 
AVVADRMVEI LFHYADRALK KCPDQGKIQV MEQHFQDTVP VIVDYCLLLQ RKDLLFGQMY 
       610        620        630        640        650        660 
DKLSENSVAK GVFLECLEPY ILSDKLVGIT PQVMKDLIVH FQDKKLLENV EALIVHMDIT 
       670        680        690        700        710        720 
SLDIQQVVLM CWENRLYDAM VYVYNRGMNE FISPMEKLFK VIAPPLNAGK TLTDEQVVMG 
       730        740        750        760        770        780 
NKLLVYISCC LAGRAYPLGD IPEDLVPLVK NQVFEFLIRL HSVEASSEEE VYPYVRTLLH 
       790        800        810        820        830        840 
FDTREFLNVL ALTFEDFKND KQAVEYQQRI VDILLKVMVE NSDFTPSQVG CLFTFLARQL 
       850        860        870        880        890        900 
AKPDNTLFVN RTLFDQVLEF LCSPDDDSRH SERQQVLLEL LQAGGIVQFE ESRLIRMAEK 
       910        920        930        940        950        960 
AEFYQICEFM YEREHQYDKI IDCYLHDPLR EEEVFNYIHN ILSIPGHSAE EKQSVWQKAM 
       970        980        990       1000       1010       1020 
NHMEELVSLK PCKAAELVAT HFSEQIEVVI GQLQNQLLLF KFLRSLLDPR EGVHVNQELL 
      1030       1040       1050       1060       1070       1080 
QIPPHITEQF IELLCQFSPD QVIQTLQVLE CYRLEETIQI TQKYQLHEVT AYLLEKKGDA 
      1090       1100       1110       1120       1130       1140 
HGAFLLLLER LQSRLQEMTR QDENTKEDIL LKGVEDTMVE TIALCQRNSQ NLNQQQREAL 
      1150       1160       1170       1180       1190       1200 
WFPLLEAMMT PQKLSSSAAA PHPHCEALKS LTMQVLNSMA AFIALPSILQ RILQDPIYGK 
      1210       1220       1230       1240       1250       1260 
GKLGEIQGLI LGMLDTFNYE QTLLETTASL LNQDLHWSLC NLRASVSRGL NPKQDYCSIC 
      1270       1280       1290       1300       1310       1320 
LQQYKRRQEM ADEIIVFSCG HLYHSFCLQS KECTLEVEGQ TRWACHKCSS SNKAGKLSEN 
      1330       1340       1350       1360       1370       1380 
PSENKKGRIT SSQVKMSPSY HQSKGDPPAR KANSEPVLDP QQMQAFDQLC RLYRGSSRLA 
      1390       1400       1410       1420    
LLTELSQNRG GDSCRPFAGP QSGPAFNSVF QKENFQLQLA PPPVAED



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q0P5W1-1-unknown METEPD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q0P5W1-1-unknown METEPD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94293
    Q0P5W1-1-unknown METEPD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94294

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PVAED 1427 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PVAED 1427 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt89912

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)