TopFIND 4.0

Q0VAA2: Leucine-rich repeat-containing protein 74A {ECO:0000312|HGNC:HGNC:23346}

General Information

Protein names
- Leucine-rich repeat-containing protein 74A {ECO:0000312|HGNC:HGNC:23346}
- Leucine-rich repeat-containing protein 74 {ECO:0000312|HGNC:HGNC:23346}
Gene names LRRC74
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q0VAA2

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MHIQFPSKPT LPRACWEGRI TAGSPGMPPD EIEIEPVRQS SDKMLYCEAE SPPTVEKVKP 
        70         80         90        100        110        120 
ARENSETDLE IEDDEKFFTT GQKELYLEAC KLMGVVPVSY FIRNMEESYV NLNHHGLGPR 
       130        140        150        160        170        180 
GTKAIAIALV SNMAVTKLEL EDNCIMEEGV LSLVEMLQEN YYLQEMNISN NHLGLEGARI 
       190        200        210        220        230        240 
ISDFFERNSS SIWSLELSGN DFKEDSAALL CQALSTNYQI KKLDLSHNQF SDVGGEHLGQ 
       250        260        270        280        290        300 
MLAINVGLTS LDLSWNNFHT RGAVALCNGL RGNVTLTKLD LSMNGFGNEV ALALGEVLRL 
       310        320        330        340        350        360 
NRCLVYLDIG GNDIGNEGAS KISKGLESNE SLRVLKLFLN PINMDGAILL ILAIKRNPKS 
       370        380        390        400        410        420 
RMEELDISNV LVSEQFMKTL DGVYAVHPQL DVVFKAVQGL SPKKTIFLLT NPMKLIQSYA 
       430        440        450        460        470        480 
DQHKITIVDF FKSLNPTGTM KMSVDEFQKV MIEQNKVPLN QYQVREVIKK LDEKTGMVNF 
   
SFLNTMKP

Isoforms

- Isoform 2 of Leucine-rich repeat-containing protein 74 - Isoform 2 of Leucine-rich repeat-containing protein 74A

Sequence View

        10         20         30         40         50         60 
MHIQFPSKPT LPRACWEGRI TAGSPGMPPD EIEIEPVRQS SDKMLYCEAE SPPTVEKVKP 
        70         80         90        100        110        120 
ARENSETDLE IEDDEKFFTT GQKELYLEAC KLMGVVPVSY FIRNMEESYV NLNHHGLGPR 
       130        140        150        160        170        180 
GTKAIAIALV SNMAVTKLEL EDNCIMEEGV LSLVEMLQEN YYLQEMNISN NHLGLEGARI 
       190        200        210        220        230        240 
ISDFFERNSS SIWSLELSGN DFKEDSAALL CQALSTNYQI KKLDLSHNQF SDVGGEHLGQ 
       250        260        270        280        290        300 
MLAINVGLTS LDLSWNNFHT RGAVALCNGL RGNVTLTKLD LSMNGFGNEV ALALGEVLRL 
       310        320        330        340        350        360 
NRCLVYLDIG GNDIGNEGAS KISKGLESNE SLRVLKLFLN PINMDGAILL ILAIKRNPKS 
       370        380        390        400        410        420 
RMEELDISNV LVSEQFMKTL DGVYAVHPQL DVVFKAVQGL SPKKTIFLLT NPMKLIQSYA 
       430        440        450        460        470        480 
DQHKITIVDF FKSLNPTGTM KMSVDEFQKV MIEQNKVPLN QYQVREVIKK LDEKTGMVNF 
   
SFLNTMKP         10         20         30         40         50         60 
MHIQFPSKPT LPRACWEGRI TAGSPGMPPD EIEIEPVRQS SDKMLYCEAE SPPTVEKVKP 
        70         80         90        100        110        120 
ARENSETDLE IEDDEKFFTT GQKELYLEAC KLMGVVPVSY FIRNMEESYV NLNHHGLGPR 
       130        140        150        160        170        180 
GTKAIAIALV SNMAVTKLEL EDNCIMEEGV LSLVEMLQEN YYLQEMNISN NHLGLEGARI 
       190        200        210        220        230        240 
ISDFFERNSS SIWSLELSGN DFKEDSAALL CQALSTNYQI KKLDLSHNQF SDVGGEHLGQ 
       250        260        270        280        290        300 
MLAINVGLTS LDLSWNNFHT RGAVALCNGL RGNVTLTKLD LSMNGFGNEV ALALGEVLRL 
       310        320        330        340        350        360 
NRCLVYLDIG GNDIGNEGAS KISKGLESNE SLRVLKLFLN PINMDGAILL ILAIKRNPKS 
       370        380        390        400        410        420 
RMEELDISNV LVSEQFMKTL DGVYAVHPQL DVVFKAVQGL SPKKTIFLLT NPMKLIQSYA 
       430        440        450        460        470        480 
DQHKITIVDF FKSLNPTGTM KMSVDEFQKV MIEQNKVPLN QYQVREVIKK LDEKTGMVNF 
   
SFLNTMKP



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q0VAA2-1-unknown MHIQFP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q0VAA2-93-unknown MGVVPV... 93 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79920

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NTMKP 488 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)