TopFIND 4.0

Q0VAM2: Ras-GEF domain-containing family member 1B

General Information

Protein names
- Ras-GEF domain-containing family member 1B
- GPI gamma-4
Gene names RASGEF1B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q0VAM2

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPQTPPFSAM FDSSGYNRNL YQSAEDSCGG LYYHDNNLLS GSLEALIQHL VPNVDYYPDR 
        70         80         90        100        110        120 
TYIFTFLLSS RLFMHPYELM AKVCHLCVEH QRLSDPDSDK NQMRKIAPKI LQLLTEWTET 
       130        140        150        160        170        180 
FPYDFRDERM MRNLKDLAHR IASGEEQTYR KNVQQMMQCL IRKLAALSQY EEVLAKISST 
       190        200        210        220        230        240 
STDRLTVLKT KPQSIQRDII TVCNDPYTLA QQLTHIELER LNYIGPEEFV QAFVQKDPLD 
       250        260        270        280        290        300 
NDKSCYSERK KTRNLEAYVE WFNRLSYLVA TEICMPVKKK HRARMIEYFI DVARECFNIG 
       310        320        330        340        350        360 
NFNSLMAIIS GMNMSPVSRL KKTWAKVKTA KFDILEHQMD PSSNFYNYRT ALRGAAQRSL 
       370        380        390        400        410        420 
TAHSSREKIV IPFFSLLIKD IYFLNEGCAN RLPNGHVNFE KFWELAKQVS EFMTWKQVEC 
       430        440        450        460        470    
PFERDRKILQ YLLTVPVFSE DALYLASYES EGPENHIEKD RWKSLRSSLL GRV

Isoforms

- Isoform 2 of Ras-GEF domain-containing family member 1B - Isoform 3 of Ras-GEF domain-containing family member 1B

Sequence View

        10         20         30         40         50         60 
MPQTPPFSAM FDSSGYNRNL YQSAEDSCGG LYYHDNNLLS GSLEALIQHL VPNVDYYPDR 
        70         80         90        100        110        120 
TYIFTFLLSS RLFMHPYELM AKVCHLCVEH QRLSDPDSDK NQMRKIAPKI LQLLTEWTET 
       130        140        150        160        170        180 
FPYDFRDERM MRNLKDLAHR IASGEEQTYR KNVQQMMQCL IRKLAALSQY EEVLAKISST 
       190        200        210        220        230        240 
STDRLTVLKT KPQSIQRDII TVCNDPYTLA QQLTHIELER LNYIGPEEFV QAFVQKDPLD 
       250        260        270        280        290        300 
NDKSCYSERK KTRNLEAYVE WFNRLSYLVA TEICMPVKKK HRARMIEYFI DVARECFNIG 
       310        320        330        340        350        360 
NFNSLMAIIS GMNMSPVSRL KKTWAKVKTA KFDILEHQMD PSSNFYNYRT ALRGAAQRSL 
       370        380        390        400        410        420 
TAHSSREKIV IPFFSLLIKD IYFLNEGCAN RLPNGHVNFE KFWELAKQVS EFMTWKQVEC 
       430        440        450        460        470    
PFERDRKILQ YLLTVPVFSE DALYLASYES EGPENHIEKD RWKSLRSSLL GRV         10         20         30         40         50         60 
MPQTPPFSAM FDSSGYNRNL YQSAEDSCGG LYYHDNNLLS GSLEALIQHL VPNVDYYPDR 
        70         80         90        100        110        120 
TYIFTFLLSS RLFMHPYELM AKVCHLCVEH QRLSDPDSDK NQMRKIAPKI LQLLTEWTET 
       130        140        150        160        170        180 
FPYDFRDERM MRNLKDLAHR IASGEEQTYR KNVQQMMQCL IRKLAALSQY EEVLAKISST 
       190        200        210        220        230        240 
STDRLTVLKT KPQSIQRDII TVCNDPYTLA QQLTHIELER LNYIGPEEFV QAFVQKDPLD 
       250        260        270        280        290        300 
NDKSCYSERK KTRNLEAYVE WFNRLSYLVA TEICMPVKKK HRARMIEYFI DVARECFNIG 
       310        320        330        340        350        360 
NFNSLMAIIS GMNMSPVSRL KKTWAKVKTA KFDILEHQMD PSSNFYNYRT ALRGAAQRSL 
       370        380        390        400        410        420 
TAHSSREKIV IPFFSLLIKD IYFLNEGCAN RLPNGHVNFE KFWELAKQVS EFMTWKQVEC 
       430        440        450        460        470    
PFERDRKILQ YLLTVPVFSE DALYLASYES EGPENHIEKD RWKSLRSSLL GRV



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q0VAM2-1-unknown MPQTPP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q0VAM2-1-unknown MPQTPP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87415
    Q0VAM2-1-unknown MPQTPP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87416

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)