Q10570: Cleavage and polyadenylation specificity factor subunit 1

General Information

Protein names	- Cleavage and polyadenylation specificity factor subunit 1 - Cleavage and polyadenylation specificity factor 160 kDa subunit - CPSF 160 kDa subunit
Gene names	CPSF1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q10570

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MYAVYKQAHP PTGLEFSMYC NFFNNSERNL VVAGTSQLYV YRLNRDAEAL TKNDRSTEGK
        70         80         90        100        110        120
AHREKLELAA SFSFFGNVMS MASVQLAGAK RDALLLSFKD AKLSVVEYDP GTHDLKTLSL
       130        140        150        160        170        180
HYFEEPELRD GFVQNVHTPR VRVDPDGRCA AMLVYGTRLV VLPFRRESLA EEHEGLVGEG
       190        200        210        220        230        240
QRSSFLPSYI IDVRALDEKL LNIIDLQFLH GYYEPTLLIL FEPNQTWPGR VAVRQDTCSI
       250        260        270        280        290        300
VAISLNITQK VHPVIWSLTS LPFDCTQALA VPKPIGGVVV FAVNSLLYLN QSVPPYGVAL
       310        320        330        340        350        360
NSLTTGTTAF PLRTQEGVRI TLDCAQATFI SYDKMVISLK GGEIYVLTLI TDGMRSVRAF
       370        380        390        400        410        420
HFDKAAASVL TTSMVTMEPG YLFLGSRLGN SLLLKYTEKL QEPPASAVRE AADKEEPPSK
       430        440        450        460        470        480
KKRVDATAGW SAAGKSVPQD EVDEIEVYGS EAQSGTQLAT YSFEVCDSIL NIGPCANAAV
       490        500        510        520        530        540
GEPAFLSEEF QNSPEPDLEI VVCSGHGKNG ALSVLQKSIR PQVVTTFELP GCYDMWTVIA
       550        560        570        580        590        600
PVRKEEEDNP KGEGTEQEPS TTPEADDDGR RHGFLILSRE DSTMILQTGQ EIMELDTSGF
       610        620        630        640        650        660
ATQGPTVFAG NIGDNRYIVQ VSPLGIRLLE GVNQLHFIPV DLGAPIVQCA VADPYVVIMS
       670        680        690        700        710        720
AEGHVTMFLL KSDSYGGRHH RLALHKPPLH HQSKVITLCL YRDLSGMFTT ESRLGGARDE
       730        740        750        760        770        780
LGGRSGPEAE GLGSETSPTV DDEEEMLYGD SGSLFSPSKE EARRSSQPPA DRDPAPFRAE
       790        800        810        820        830        840
PTHWCLLVRE NGTMEIYQLP DWRLVFLVKN FPVGQRVLVD SSFGQPTTQG EARREEATRQ
       850        860        870        880        890        900
GELPLVKEVL LVALGSRQSR PYLLVHVDQE LLIYEAFPHD SQLGQGNLKV RFKKVPHNIN
       910        920        930        940        950        960
FREKKPKPSK KKAEGGGAEE GAGARGRVAR FRYFEDIYGY SGVFICGPSP HWLLVTGRGA
       970        980        990       1000       1010       1020
LRLHPMAIDG PVDSFAPFHN VNCPRGFLYF NRQGELRISV LPAYLSYDAP WPVRKIPLRC
      1030       1040       1050       1060       1070       1080
TAHYVAYHVE SKVYAVATST NTPCARIPRM TGEEKEFETI ERDERYIHPQ QEAFSIQLIS
      1090       1100       1110       1120       1130       1140
PVSWEAIPNA RIELQEWEHV TCMKTVSLRS EETVSGLKGY VAAGTCLMQG EEVTCRGRIL
      1150       1160       1170       1180       1190       1200
IMDVIEVVPE PGQPLTKNKF KVLYEKEQKG PVTALCHCNG HLVSAIGQKI FLWSLRASEL
      1210       1220       1230       1240       1250       1260
TGMAFIDTQL YIHQMISVKN FILAADVMKS ISLLRYQEES KTLSLVSRDA KPLEVYSVDF
      1270       1280       1290       1300       1310       1320
MVDNAQLGFL VSDRDRNLMV YMYLPEAKES FGGMRLLRRA DFHVGAHVNT FWRTPCRGAT
      1330       1340       1350       1360       1370       1380
EGLSKKSVVW ENKHITWFAT LDGGIGLLLP MQEKTYRRLL MLQNALTTML PHHAGLNPRA
      1390       1400       1410       1420       1430       1440
FRMLHVDRRT LQNAVRNVLD GELLNRYLYL STMERSELAK KIGTTPDIIL DDLLETDRVT

AHF

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q10570-1-unknown	MYAVYK...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q10570-1228-unknown	MKSISL...	1228		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000454354

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AEEHEG	174	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435761
...HITWFA	1338	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457485
...VTAHF	1443	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)