Q12303: Aspartic proteinase yapsin-3
| Protein names | - Aspartic proteinase yapsin-3 - 3.4.23.- |
|---|---|
| Gene names | YPS3 |
| Organism | Saccharomyces cerevisiae |
| Protease Family | A01.035 |
| Protease ID | A01.035 |
| Chromosome location | |
| UniProt ID | Q12303 |
3
N-termini
3
C-termini
3
Cleavages
2
Substrates
Sequence
10 20 30 40 50 60
MKLQLAAVAT LAVLTSPAFG RVLPDGKYVK IPFTKKKNGD NGELSKRSNG HEKFVLANEQ
70 80 90 100 110 120
SFYSVELAIG TPSQNLTVLL DTGSADLWVP GKGNPYCGSV MDCDQYGVFD KTKSSTFKAN
130 140 150 160 170 180
KSSPFYAAYG DGTYAEGAFG QDKLKYNELD LSGLSFAVAN ESNSTFGVLG IGLSTLEVTY
190 200 210 220 230 240
SGKVAIMDKR SYEYDNFPLF LKHSGAIDAT AYSLFLNDES QSSGSILFGA VDHSKYEGQL
250 260 270 280 290 300
YTIPLVNLYK SQGYQHPVAF DVTLQGLGLQ TDKRNITLTT TKLPALLDSG TTLTYLPSQA
310 320 330 340 350 360
VALLAKSLNA SYSKTLGYYE YTCPSSDNKT SVAFDFGGFR INAPLSDFTM QTSVGTCVLA
370 380 390 400 410 420
IIPQAGNATA ILGDSFLRNA YVVYDLDNYE ISLAQAKYGT GKENVEVIKS TVPSAIRAPS
430 440 450 460 470 480
YNNTWSNYAS ATSGGNIFTT VRTFNGTSTA TTTRSTTTKK TNSTTTAKST HKSKRALQRA
490 500
ATNSASSIRS TLGLLLVPSL LILSVFFS
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 3 Cleavages - 2 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q12303-21-unknown | RVLPDG... | 21 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q12303-48-unknown | SNGHEK... | 48 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q12303-48-unknown | SNGHEK... | 48 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32048 | |||
| Q12303-48-unknown | SNGHEK... | 48 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32676 | |||
| Q12303-54-unknown | FVLANE... | 54 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32677 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...ELSKRS | 47 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32048 | |||
| ...ELSKRS | 47 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32676 | |||
| ...NGHEKF | 53 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32677 | |||
| ...RAATNS | 483 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| KEX2_YEAST | 47 | SKRS.|.SNGH | inferred from experiment | unknown | MEROPS | Hube B | Bader O et al.:Processing of predicted substra... (S08.070) | 18625069, |
| YPS3_YEAST | 47 | SKRS.|.SNGH | inferred from experiment | unknown | MEROPS | Loh YP | Olsen V et al.:Identification and characteriza... (A01.035) | 10191273, |
| YPS3_YEAST | 53 | HEKF.|.FVLA | inferred from experiment | unknown | MEROPS | Loh YP | Olsen V et al.:Identification and characteriza... (A01.035) | 10191273, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| YPS3_YEAST | 47 | SKRS.|.SNGH | inferred from experiment | unknown | MEROPS | Loh YP | Olsen V et al.:Identification and characteriza... (A01.035) | 10191273, |
| YPS3_YEAST | 53 | HEKF.|.FVLA | inferred from experiment | unknown | MEROPS | Loh YP | Olsen V et al.:Identification and characteriza... (A01.035) | 10191273, |