Q13002: Glutamate receptor ionotropic, kainate 2

General Information

Protein names	- Glutamate receptor ionotropic, kainate 2 - GluK2 - Excitatory amino acid receptor 4 - EAA4 - Glutamate receptor 6 - GluR-6 - GluR6
Gene names	GRIK2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13002

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKIIFPILSN PVFRRTVKLL LCLLWIGYSQ GTTHVLRFGG IFEYVESGPM GAEELAFRFA
        70         80         90        100        110        120
VNTINRNRTL LPNTTLTYDT QKINLYDSFE ASKKACDQLS LGVAAIFGPS HSSSANAVQS
       130        140        150        160        170        180
ICNALGVPHI QTRWKHQVSD NKDSFYVSLY PDFSSLSRAI LDLVQFFKWK TVTVVYDDST
       190        200        210        220        230        240
GLIRLQELIK APSRYNLRLK IRQLPADTKD AKPLLKEMKR GKEFHVIFDC SHEMAAGILK
       250        260        270        280        290        300
QALAMGMMTE YYHYIFTTLD LFALDVEPYR YSGVNMTGFR ILNTENTQVS SIIEKWSMER
       310        320        330        340        350        360
LQAPPKPDSG LLDGFMTTDA ALMYDAVHVV SVAVQQFPQM TVSSLQCNRH KPWRFGTRFM
       370        380        390        400        410        420
SLIKEAHWEG LTGRITFNKT NGLRTDFDLD VISLKEEGLE KIGTWDPASG LNMTESQKGK
       430        440        450        460        470        480
PANITDSLSN RSLIVTTILE EPYVLFKKSD KPLYGNDRFE GYCIDLLREL STILGFTYEI
       490        500        510        520        530        540
RLVEDGKYGA QDDANGQWNG MVRELIDHKA DLAVAPLAIT YVREKVIDFS KPFMTLGISI
       550        560        570        580        590        600
LYRKPNGTNP GVFSFLNPLS PDIWMYILLA YLGVSCVLFV IARFSPYEWY NPHPCNPDSD
       610        620        630        640        650        660
VVENNFTLLN SFWFGVGALM QQGSELMPKA LSTRIVGGIW WFFTLIIISS YTANLAAFLT
       670        680        690        700        710        720
VERMESPIDS ADDLAKQTKI EYGAVEDGAT MTFFKKSKIS TYDKMWAFMS SRRQSVLVKS
       730        740        750        760        770        780
NEEGIQRVLT SDYAFLMEST TIEFVTQRNC NLTQIGGLID SKGYGVGTPM GSPYRDKITI
       790        800        810        820        830        840
AILQLQEEGK LHMMKEKWWR GNGCPEEESK EASALGVQNI GGIFIVLAAG LVLSVFVAVG
       850        860        870        880        890        900
EFLYKSKKNA QLEKRSFCSA MVEELRMSLK CQRRLKHKPQ APVIVKTEEV INMHTFNDRR

LPGKETMA

Isoforms

- Isoform 2 of Glutamate receptor ionotropic, kainate 2 - Isoform 3 of Glutamate receptor ionotropic, kainate 2 - Isoform 4 of Glutamate receptor ionotropic, kainate 2 - Isoform 5 of Glutamate receptor ionotropic, kainate 2 - Isoform 6 of Glutamate receptor ionotropic, kainate 2 - Isoform 7 of Glutamate receptor ionotropic, kainate 2

Sequence View

        10         20         30         40         50         60
MKIIFPILSN PVFRRTVKLL LCLLWIGYSQ GTTHVLRFGG IFEYVESGPM GAEELAFRFA
        70         80         90        100        110        120
VNTINRNRTL LPNTTLTYDT QKINLYDSFE ASKKACDQLS LGVAAIFGPS HSSSANAVQS
       130        140        150        160        170        180
ICNALGVPHI QTRWKHQVSD NKDSFYVSLY PDFSSLSRAI LDLVQFFKWK TVTVVYDDST
       190        200        210        220        230        240
GLIRLQELIK APSRYNLRLK IRQLPADTKD AKPLLKEMKR GKEFHVIFDC SHEMAAGILK
       250        260        270        280        290        300
QALAMGMMTE YYHYIFTTLD LFALDVEPYR YSGVNMTGFR ILNTENTQVS SIIEKWSMER
       310        320        330        340        350        360
LQAPPKPDSG LLDGFMTTDA ALMYDAVHVV SVAVQQFPQM TVSSLQCNRH KPWRFGTRFM
       370        380        390        400        410        420
SLIKEAHWEG LTGRITFNKT NGLRTDFDLD VISLKEEGLE KIGTWDPASG LNMTESQKGK
       430        440        450        460        470        480
PANITDSLSN RSLIVTTILE EPYVLFKKSD KPLYGNDRFE GYCIDLLREL STILGFTYEI
       490        500        510        520        530        540
RLVEDGKYGA QDDANGQWNG MVRELIDHKA DLAVAPLAIT YVREKVIDFS KPFMTLGISI
       550        560        570        580        590        600
LYRKPNGTNP GVFSFLNPLS PDIWMYILLA YLGVSCVLFV IARFSPYEWY NPHPCNPDSD
       610        620        630        640        650        660
VVENNFTLLN SFWFGVGALM QQGSELMPKA LSTRIVGGIW WFFTLIIISS YTANLAAFLT
       670        680        690        700        710        720
VERMESPIDS ADDLAKQTKI EYGAVEDGAT MTFFKKSKIS TYDKMWAFMS SRRQSVLVKS
       730        740        750        760        770        780
NEEGIQRVLT SDYAFLMEST TIEFVTQRNC NLTQIGGLID SKGYGVGTPM GSPYRDKITI
       790        800        810        820        830        840
AILQLQEEGK LHMMKEKWWR GNGCPEEESK EASALGVQNI GGIFIVLAAG LVLSVFVAVG
       850        860        870        880        890        900
EFLYKSKKNA QLEKRSFCSA MVEELRMSLK CQRRLKHKPQ APVIVKTEEV INMHTFNDRR

LPGKETMA         10         20         30         40         50         60
MKIIFPILSN PVFRRTVKLL LCLLWIGYSQ GTTHVLRFGG IFEYVESGPM GAEELAFRFA
        70         80         90        100        110        120
VNTINRNRTL LPNTTLTYDT QKINLYDSFE ASKKACDQLS LGVAAIFGPS HSSSANAVQS
       130        140        150        160        170        180
ICNALGVPHI QTRWKHQVSD NKDSFYVSLY PDFSSLSRAI LDLVQFFKWK TVTVVYDDST
       190        200        210        220        230        240
GLIRLQELIK APSRYNLRLK IRQLPADTKD AKPLLKEMKR GKEFHVIFDC SHEMAAGILK
       250        260        270        280        290        300
QALAMGMMTE YYHYIFTTLD LFALDVEPYR YSGVNMTGFR ILNTENTQVS SIIEKWSMER
       310        320        330        340        350        360
LQAPPKPDSG LLDGFMTTDA ALMYDAVHVV SVAVQQFPQM TVSSLQCNRH KPWRFGTRFM
       370        380        390        400        410        420
SLIKEAHWEG LTGRITFNKT NGLRTDFDLD VISLKEEGLE KIGTWDPASG LNMTESQKGK
       430        440        450        460        470        480
PANITDSLSN RSLIVTTILE EPYVLFKKSD KPLYGNDRFE GYCIDLLREL STILGFTYEI
       490        500        510        520        530        540
RLVEDGKYGA QDDANGQWNG MVRELIDHKA DLAVAPLAIT YVREKVIDFS KPFMTLGISI
       550        560        570        580        590        600
LYRKPNGTNP GVFSFLNPLS PDIWMYILLA YLGVSCVLFV IARFSPYEWY NPHPCNPDSD
       610        620        630        640        650        660
VVENNFTLLN SFWFGVGALM QQGSELMPKA LSTRIVGGIW WFFTLIIISS YTANLAAFLT
       670        680        690        700        710        720
VERMESPIDS ADDLAKQTKI EYGAVEDGAT MTFFKKSKIS TYDKMWAFMS SRRQSVLVKS
       730        740        750        760        770        780
NEEGIQRVLT SDYAFLMEST TIEFVTQRNC NLTQIGGLID SKGYGVGTPM GSPYRDKITI
       790        800        810        820        830        840
AILQLQEEGK LHMMKEKWWR GNGCPEEESK EASALGVQNI GGIFIVLAAG LVLSVFVAVG
       850        860        870        880        890        900
EFLYKSKKNA QLEKRSFCSA MVEELRMSLK CQRRLKHKPQ APVIVKTEEV INMHTFNDRR

LPGKETMA         10         20         30         40         50         60
MKIIFPILSN PVFRRTVKLL LCLLWIGYSQ GTTHVLRFGG IFEYVESGPM GAEELAFRFA
        70         80         90        100        110        120
VNTINRNRTL LPNTTLTYDT QKINLYDSFE ASKKACDQLS LGVAAIFGPS HSSSANAVQS
       130        140        150        160        170        180
ICNALGVPHI QTRWKHQVSD NKDSFYVSLY PDFSSLSRAI LDLVQFFKWK TVTVVYDDST
       190        200        210        220        230        240
GLIRLQELIK APSRYNLRLK IRQLPADTKD AKPLLKEMKR GKEFHVIFDC SHEMAAGILK
       250        260        270        280        290        300
QALAMGMMTE YYHYIFTTLD LFALDVEPYR YSGVNMTGFR ILNTENTQVS SIIEKWSMER
       310        320        330        340        350        360
LQAPPKPDSG LLDGFMTTDA ALMYDAVHVV SVAVQQFPQM TVSSLQCNRH KPWRFGTRFM
       370        380        390        400        410        420
SLIKEAHWEG LTGRITFNKT NGLRTDFDLD VISLKEEGLE KIGTWDPASG LNMTESQKGK
       430        440        450        460        470        480
PANITDSLSN RSLIVTTILE EPYVLFKKSD KPLYGNDRFE GYCIDLLREL STILGFTYEI
       490        500        510        520        530        540
RLVEDGKYGA QDDANGQWNG MVRELIDHKA DLAVAPLAIT YVREKVIDFS KPFMTLGISI
       550        560        570        580        590        600
LYRKPNGTNP GVFSFLNPLS PDIWMYILLA YLGVSCVLFV IARFSPYEWY NPHPCNPDSD
       610        620        630        640        650        660
VVENNFTLLN SFWFGVGALM QQGSELMPKA LSTRIVGGIW WFFTLIIISS YTANLAAFLT
       670        680        690        700        710        720
VERMESPIDS ADDLAKQTKI EYGAVEDGAT MTFFKKSKIS TYDKMWAFMS SRRQSVLVKS
       730        740        750        760        770        780
NEEGIQRVLT SDYAFLMEST TIEFVTQRNC NLTQIGGLID SKGYGVGTPM GSPYRDKITI
       790        800        810        820        830        840
AILQLQEEGK LHMMKEKWWR GNGCPEEESK EASALGVQNI GGIFIVLAAG LVLSVFVAVG
       850        860        870        880        890        900
EFLYKSKKNA QLEKRSFCSA MVEELRMSLK CQRRLKHKPQ APVIVKTEEV INMHTFNDRR

LPGKETMA         10         20         30         40         50         60
MKIIFPILSN PVFRRTVKLL LCLLWIGYSQ GTTHVLRFGG IFEYVESGPM GAEELAFRFA
        70         80         90        100        110        120
VNTINRNRTL LPNTTLTYDT QKINLYDSFE ASKKACDQLS LGVAAIFGPS HSSSANAVQS
       130        140        150        160        170        180
ICNALGVPHI QTRWKHQVSD NKDSFYVSLY PDFSSLSRAI LDLVQFFKWK TVTVVYDDST
       190        200        210        220        230        240
GLIRLQELIK APSRYNLRLK IRQLPADTKD AKPLLKEMKR GKEFHVIFDC SHEMAAGILK
       250        260        270        280        290        300
QALAMGMMTE YYHYIFTTLD LFALDVEPYR YSGVNMTGFR ILNTENTQVS SIIEKWSMER
       310        320        330        340        350        360
LQAPPKPDSG LLDGFMTTDA ALMYDAVHVV SVAVQQFPQM TVSSLQCNRH KPWRFGTRFM
       370        380        390        400        410        420
SLIKEAHWEG LTGRITFNKT NGLRTDFDLD VISLKEEGLE KIGTWDPASG LNMTESQKGK
       430        440        450        460        470        480
PANITDSLSN RSLIVTTILE EPYVLFKKSD KPLYGNDRFE GYCIDLLREL STILGFTYEI
       490        500        510        520        530        540
RLVEDGKYGA QDDANGQWNG MVRELIDHKA DLAVAPLAIT YVREKVIDFS KPFMTLGISI
       550        560        570        580        590        600
LYRKPNGTNP GVFSFLNPLS PDIWMYILLA YLGVSCVLFV IARFSPYEWY NPHPCNPDSD
       610        620        630        640        650        660
VVENNFTLLN SFWFGVGALM QQGSELMPKA LSTRIVGGIW WFFTLIIISS YTANLAAFLT
       670        680        690        700        710        720
VERMESPIDS ADDLAKQTKI EYGAVEDGAT MTFFKKSKIS TYDKMWAFMS SRRQSVLVKS
       730        740        750        760        770        780
NEEGIQRVLT SDYAFLMEST TIEFVTQRNC NLTQIGGLID SKGYGVGTPM GSPYRDKITI
       790        800        810        820        830        840
AILQLQEEGK LHMMKEKWWR GNGCPEEESK EASALGVQNI GGIFIVLAAG LVLSVFVAVG
       850        860        870        880        890        900
EFLYKSKKNA QLEKRSFCSA MVEELRMSLK CQRRLKHKPQ APVIVKTEEV INMHTFNDRR

LPGKETMA         10         20         30         40         50         60
MKIIFPILSN PVFRRTVKLL LCLLWIGYSQ GTTHVLRFGG IFEYVESGPM GAEELAFRFA
        70         80         90        100        110        120
VNTINRNRTL LPNTTLTYDT QKINLYDSFE ASKKACDQLS LGVAAIFGPS HSSSANAVQS
       130        140        150        160        170        180
ICNALGVPHI QTRWKHQVSD NKDSFYVSLY PDFSSLSRAI LDLVQFFKWK TVTVVYDDST
       190        200        210        220        230        240
GLIRLQELIK APSRYNLRLK IRQLPADTKD AKPLLKEMKR GKEFHVIFDC SHEMAAGILK
       250        260        270        280        290        300
QALAMGMMTE YYHYIFTTLD LFALDVEPYR YSGVNMTGFR ILNTENTQVS SIIEKWSMER
       310        320        330        340        350        360
LQAPPKPDSG LLDGFMTTDA ALMYDAVHVV SVAVQQFPQM TVSSLQCNRH KPWRFGTRFM
       370        380        390        400        410        420
SLIKEAHWEG LTGRITFNKT NGLRTDFDLD VISLKEEGLE KIGTWDPASG LNMTESQKGK
       430        440        450        460        470        480
PANITDSLSN RSLIVTTILE EPYVLFKKSD KPLYGNDRFE GYCIDLLREL STILGFTYEI
       490        500        510        520        530        540
RLVEDGKYGA QDDANGQWNG MVRELIDHKA DLAVAPLAIT YVREKVIDFS KPFMTLGISI
       550        560        570        580        590        600
LYRKPNGTNP GVFSFLNPLS PDIWMYILLA YLGVSCVLFV IARFSPYEWY NPHPCNPDSD
       610        620        630        640        650        660
VVENNFTLLN SFWFGVGALM QQGSELMPKA LSTRIVGGIW WFFTLIIISS YTANLAAFLT
       670        680        690        700        710        720
VERMESPIDS ADDLAKQTKI EYGAVEDGAT MTFFKKSKIS TYDKMWAFMS SRRQSVLVKS
       730        740        750        760        770        780
NEEGIQRVLT SDYAFLMEST TIEFVTQRNC NLTQIGGLID SKGYGVGTPM GSPYRDKITI
       790        800        810        820        830        840
AILQLQEEGK LHMMKEKWWR GNGCPEEESK EASALGVQNI GGIFIVLAAG LVLSVFVAVG
       850        860        870        880        890        900
EFLYKSKKNA QLEKRSFCSA MVEELRMSLK CQRRLKHKPQ APVIVKTEEV INMHTFNDRR

LPGKETMA         10         20         30         40         50         60
MKIIFPILSN PVFRRTVKLL LCLLWIGYSQ GTTHVLRFGG IFEYVESGPM GAEELAFRFA
        70         80         90        100        110        120
VNTINRNRTL LPNTTLTYDT QKINLYDSFE ASKKACDQLS LGVAAIFGPS HSSSANAVQS
       130        140        150        160        170        180
ICNALGVPHI QTRWKHQVSD NKDSFYVSLY PDFSSLSRAI LDLVQFFKWK TVTVVYDDST
       190        200        210        220        230        240
GLIRLQELIK APSRYNLRLK IRQLPADTKD AKPLLKEMKR GKEFHVIFDC SHEMAAGILK
       250        260        270        280        290        300
QALAMGMMTE YYHYIFTTLD LFALDVEPYR YSGVNMTGFR ILNTENTQVS SIIEKWSMER
       310        320        330        340        350        360
LQAPPKPDSG LLDGFMTTDA ALMYDAVHVV SVAVQQFPQM TVSSLQCNRH KPWRFGTRFM
       370        380        390        400        410        420
SLIKEAHWEG LTGRITFNKT NGLRTDFDLD VISLKEEGLE KIGTWDPASG LNMTESQKGK
       430        440        450        460        470        480
PANITDSLSN RSLIVTTILE EPYVLFKKSD KPLYGNDRFE GYCIDLLREL STILGFTYEI
       490        500        510        520        530        540
RLVEDGKYGA QDDANGQWNG MVRELIDHKA DLAVAPLAIT YVREKVIDFS KPFMTLGISI
       550        560        570        580        590        600
LYRKPNGTNP GVFSFLNPLS PDIWMYILLA YLGVSCVLFV IARFSPYEWY NPHPCNPDSD
       610        620        630        640        650        660
VVENNFTLLN SFWFGVGALM QQGSELMPKA LSTRIVGGIW WFFTLIIISS YTANLAAFLT
       670        680        690        700        710        720
VERMESPIDS ADDLAKQTKI EYGAVEDGAT MTFFKKSKIS TYDKMWAFMS SRRQSVLVKS
       730        740        750        760        770        780
NEEGIQRVLT SDYAFLMEST TIEFVTQRNC NLTQIGGLID SKGYGVGTPM GSPYRDKITI
       790        800        810        820        830        840
AILQLQEEGK LHMMKEKWWR GNGCPEEESK EASALGVQNI GGIFIVLAAG LVLSVFVAVG
       850        860        870        880        890        900
EFLYKSKKNA QLEKRSFCSA MVEELRMSLK CQRRLKHKPQ APVIVKTEEV INMHTFNDRR

LPGKETMA

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q13002-1-unknown	MKIIFP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76445
Q13002-1-unknown	MKIIFP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76446
Q13002-1-unknown	MKIIFP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76447
Q13002-1-unknown	MKIIFP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76448
Q13002-1-unknown	MKIIFP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76449
Q13002-1-unknown	MKIIFP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt76450
Q13002-32-unknown	TTHVLR...	32	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q13002-32-unknown	TTHVLR...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114902
Q13002-32-unknown	TTHVLR...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114903
Q13002-32-unknown	TTHVLR...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114904
Q13002-32-unknown	TTHVLR...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114905
Q13002-32-unknown	TTHVLR...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114906
Q13002-32-unknown	TTHVLR...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114907

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VIARFS	584	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72064
...VIARFS	584	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93091
...VIARFS	584	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93092
...KETMA	908	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KETMA	908	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72065

TopFIND

Q13002: Glutamate receptor ionotropic, kainate 2

General Information

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates