TopFIND 4.0

Q13087: Protein disulfide-isomerase A2

General Information

Protein names
- Protein disulfide-isomerase A2
- 5.3.4.1
- Pancreas-specific protein disulfide isomerase
- PDIp
Gene names PDIA2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q13087

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSRQLLPVLL LLLLRASCPW GQEQGARSPS EEPPEEEIPK EDGILVLSRH TLGLALREHP 
        70         80         90        100        110        120 
ALLVEFYAPW CGHCQALAPE YSKAAAVLAA ESMVVTLAKV DGPAQRELAE EFGVTEYPTL 
       130        140        150        160        170        180 
KFFRNGNRTH PEEYTGPRDA EGIAEWLRRR VGPSAMRLED EAAAQALIGG RDLVVIGFFQ 
       190        200        210        220        230        240 
DLQDEDVATF LALAQDALDM TFGLTDRPRL FQQFGLTKDT VVLFKKFDEG RADFPVDEEL 
       250        260        270        280        290        300 
GLDLGDLSRF LVTHSMRLVT EFNSQTSAKI FAARILNHLL LFVNQTLAAH RELLAGFGEA 
       310        320        330        340        350        360 
APRFRGQVLF VVVDVAADNE HVLQYFGLKA EAAPTLRLVN LETTKKYAPV DGGPVTAASI 
       370        380        390        400        410        420 
TAFCHAVLNG QVKPYLLSQE IPPDWDQRPV KTLVGKNFEQ VAFDETKNVF VKFYAPWCTH 
       430        440        450        460        470        480 
CKEMAPAWEA LAEKYQDHED IIIAELDATA NELDAFAVHG FPTLKYFPAG PGRKVIEYKS 
       490        500        510        520    
TRDLETFSKF LDNGGVLPTE EPPEEPAAPF PEPPANSTMG SKEEL

Isoforms

- Isoform 2 of Protein disulfide-isomerase A2

Sequence View

        10         20         30         40         50         60 
MSRQLLPVLL LLLLRASCPW GQEQGARSPS EEPPEEEIPK EDGILVLSRH TLGLALREHP 
        70         80         90        100        110        120 
ALLVEFYAPW CGHCQALAPE YSKAAAVLAA ESMVVTLAKV DGPAQRELAE EFGVTEYPTL 
       130        140        150        160        170        180 
KFFRNGNRTH PEEYTGPRDA EGIAEWLRRR VGPSAMRLED EAAAQALIGG RDLVVIGFFQ 
       190        200        210        220        230        240 
DLQDEDVATF LALAQDALDM TFGLTDRPRL FQQFGLTKDT VVLFKKFDEG RADFPVDEEL 
       250        260        270        280        290        300 
GLDLGDLSRF LVTHSMRLVT EFNSQTSAKI FAARILNHLL LFVNQTLAAH RELLAGFGEA 
       310        320        330        340        350        360 
APRFRGQVLF VVVDVAADNE HVLQYFGLKA EAAPTLRLVN LETTKKYAPV DGGPVTAASI 
       370        380        390        400        410        420 
TAFCHAVLNG QVKPYLLSQE IPPDWDQRPV KTLVGKNFEQ VAFDETKNVF VKFYAPWCTH 
       430        440        450        460        470        480 
CKEMAPAWEA LAEKYQDHED IIIAELDATA NELDAFAVHG FPTLKYFPAG PGRKVIEYKS 
       490        500        510        520    
TRDLETFSKF LDNGGVLPTE EPPEEPAAPF PEPPANSTMG SKEEL



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q13087-1-unknown MSRQLL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt84742
    Q13087-22-unknown QEQGAR... 22 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q13087-22-unknown QEQGAR... 22 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112941

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SKEEL 525 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SKEEL 525 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt80360

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)