Q13275: Semaphorin-3F
Protein names | - Semaphorin-3F - Sema III/F - Semaphorin IV - Sema IV |
---|---|
Gene names | SEMA3F |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q13275 |
3
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MLVAGLLLWA SLLTGAWPSF PTQDHLPATP RVRLSFKELK ATGTAHFFNF LLNTTDYRIL
70 80 90 100 110 120
LKDEDHDRMY VGSKDYVLSL DLHDINREPL IIHWAASPQR IEECVLSGKD VNGECGNFVR
130 140 150 160 170 180
LIQPWNRTHL YVCGTGAYNP MCTYVNRGRR AQATPWTQTQ AVRGRGSRAT DGALRPMPTA
190 200 210 220 230 240
PRQDYIFYLE PERLESGKGK CPYDPKLDTA SALINEELYA GVYIDFMGTD AAIFRTLGKQ
250 260 270 280 290 300
TAMRTDQYNS RWLNDPSFIH AELIPDSAER NDDKLYFFFR ERSAEAPQSP AVYARIGRIC
310 320 330 340 350 360
LNDDGGHCCL VNKWSTFLKA RLVCSVPGED GIETHFDELQ DVFVQQTQDV RNPVIYAVFT
370 380 390 400 410 420
SSGSVFRGSA VCVYSMADIR MVFNGPFAHK EGPNYQWMPF SGKMPYPRPG TCPGGTFTPS
430 440 450 460 470 480
MKSTKDYPDE VINFMRSHPL MYQAVYPLQR RPLVVRTGAP YRLTTIAVDQ VDAADGRYEV
490 500 510 520 530 540
LFLGTDRGTV QKVIVLPKDD QELEELMLEE VEVFKDPAPV KTMTISSKRQ QLYVASAVGV
550 560 570 580 590 600
THLSLHRCQA YGAACADCCL ARDPYCAWDG QACSRYTASS KRRSRRQDVR HGNPIRQCRG
610 620 630 640 650 660
FNSNANKNAV ESVQYGVAGS AAFLECQPRS PQATVKWLFQ RDPGDRRREI RAEDRFLRTE
670 680 690 700 710 720
QGLLLRALQL SDRGLYSCTA TENNFKHVVT RVQLHVLGRD AVHAALFPPL SMSAPPPPGA
730 740 750 760 770 780
GPPTPPYQEL AQLLAQPEVG LIHQYCQGYW RHVPPSPREA PGAPRSPEPQ DQKKPRNRRH
HPPDT
Isoforms
- Isoform 2 of Semaphorin-3FSequence View
10 20 30 40 50 60
MLVAGLLLWA SLLTGAWPSF PTQDHLPATP RVRLSFKELK ATGTAHFFNF LLNTTDYRIL
70 80 90 100 110 120
LKDEDHDRMY VGSKDYVLSL DLHDINREPL IIHWAASPQR IEECVLSGKD VNGECGNFVR
130 140 150 160 170 180
LIQPWNRTHL YVCGTGAYNP MCTYVNRGRR AQATPWTQTQ AVRGRGSRAT DGALRPMPTA
190 200 210 220 230 240
PRQDYIFYLE PERLESGKGK CPYDPKLDTA SALINEELYA GVYIDFMGTD AAIFRTLGKQ
250 260 270 280 290 300
TAMRTDQYNS RWLNDPSFIH AELIPDSAER NDDKLYFFFR ERSAEAPQSP AVYARIGRIC
310 320 330 340 350 360
LNDDGGHCCL VNKWSTFLKA RLVCSVPGED GIETHFDELQ DVFVQQTQDV RNPVIYAVFT
370 380 390 400 410 420
SSGSVFRGSA VCVYSMADIR MVFNGPFAHK EGPNYQWMPF SGKMPYPRPG TCPGGTFTPS
430 440 450 460 470 480
MKSTKDYPDE VINFMRSHPL MYQAVYPLQR RPLVVRTGAP YRLTTIAVDQ VDAADGRYEV
490 500 510 520 530 540
LFLGTDRGTV QKVIVLPKDD QELEELMLEE VEVFKDPAPV KTMTISSKRQ QLYVASAVGV
550 560 570 580 590 600
THLSLHRCQA YGAACADCCL ARDPYCAWDG QACSRYTASS KRRSRRQDVR HGNPIRQCRG
610 620 630 640 650 660
FNSNANKNAV ESVQYGVAGS AAFLECQPRS PQATVKWLFQ RDPGDRRREI RAEDRFLRTE
670 680 690 700 710 720
QGLLLRALQL SDRGLYSCTA TENNFKHVVT RVQLHVLGRD AVHAALFPPL SMSAPPPPGA
730 740 750 760 770 780
GPPTPPYQEL AQLLAQPEVG LIHQYCQGYW RHVPPSPREA PGAPRSPEPQ DQKKPRNRRH
HPPDT
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q13275-1-unknown | MLVAGL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt89214 | |||
Q13275-19-unknown | SFPTQD... | 19 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q13275-19-unknown | SFPTQD... | 19 | unknown | Wildes D. et al: Sampling the N-terminal proteome of human blood | 20173099 | ||||
Q13275-19-unknown | SFPTQD... | 19 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt112237 | |||
Q13275-780-unknown | HHPPDT... | 780 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9786 | |||
Q13275-780-unknown | HHPPDT... | 780 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156265 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...PRNRRH | 779 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC9786 | |||
...PRNRRH | 779 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139734 | |||
...HPPDT | 785 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...HPPDT | 785 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt84832 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
FURIN_HUMAN | 779 | NRRH.|.HHPP | inferred from experiment | unknown | MEROPS | Vander Kooi CW | Parker MW et al.:Furin processing of semaphorin ... (S08.071) | 20387901, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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