Q13418: Integrin-linked protein kinase

General Information

Protein names	- Integrin-linked protein kinase - 2.7.11.1 - 59 kDa serine/threonine-protein kinase - ILK-1 - ILK-2 - p59ILK
Gene names	ILK
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13418

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Integrin-linked protein kinase - Isoform 3 of Integrin-linked protein kinase

Sequence View

        10         20         30         40         50         60
MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW ACREGRSAVV EMLIMRGARI
        70         80         90        100        110        120
NVMNRGDDTP LHLAASHGHR DIVQKLLQYK ADINAVNEHG NVPLHYACFW GQDQVAEDLV
       130        140        150        160        170        180
ANGALVSICN KYGEMPVDKA KAPLRELLRE RAEKMGQNLN RIPYKDTFWK GTTRTRPRNG
       190        200        210        220        230        240
TLNKHSGIDF KQLNFLTKLN ENHSGELWKG RWQGNDIVVK VLKVRDWSTR KSRDFNEECP
       250        260        270        280        290        300
RLRIFSHPNV LPVLGACQSP PAPHPTLITH WMPYGSLYNV LHEGTNFVVD QSQAVKFALD
       310        320        330        340        350        360
MARGMAFLHT LEPLIPRHAL NSRSVMIDED MTARISMADV KFSFQCPGRM YAPAWVAPEA
       370        380        390        400        410        420
LQKKPEDTNR RSADMWSFAV LLWELVTREV PFADLSNMEI GMKVALEGLR PTIPPGISPH
       430        440        450
VCKLMKICMN EDPAKRPKFD MIVPILEKMQ DK         10         20         30         40         50         60
MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW ACREGRSAVV EMLIMRGARI
        70         80         90        100        110        120
NVMNRGDDTP LHLAASHGHR DIVQKLLQYK ADINAVNEHG NVPLHYACFW GQDQVAEDLV
       130        140        150        160        170        180
ANGALVSICN KYGEMPVDKA KAPLRELLRE RAEKMGQNLN RIPYKDTFWK GTTRTRPRNG
       190        200        210        220        230        240
TLNKHSGIDF KQLNFLTKLN ENHSGELWKG RWQGNDIVVK VLKVRDWSTR KSRDFNEECP
       250        260        270        280        290        300
RLRIFSHPNV LPVLGACQSP PAPHPTLITH WMPYGSLYNV LHEGTNFVVD QSQAVKFALD
       310        320        330        340        350        360
MARGMAFLHT LEPLIPRHAL NSRSVMIDED MTARISMADV KFSFQCPGRM YAPAWVAPEA
       370        380        390        400        410        420
LQKKPEDTNR RSADMWSFAV LLWELVTREV PFADLSNMEI GMKVALEGLR PTIPPGISPH
       430        440        450
VCKLMKICMN EDPAKRPKFD MIVPILEKMQ DK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13418-1-Acetylation	MDDIFT...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13418-1-Acetylation	MDDIFT...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q13418-1-Acetylation	MDDIFT...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q13418-1-Acetylation	MDDIFT...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q13418-1-Acetylation	MDDIFT...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt104919
Q13418-1-unknown	MDDIFT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt77831
Q13418-135-unknown	MPVDKA...	135		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000439606

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...KMQDK	452	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...KMQDK	452	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt73449
...KMQDK	452		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KMQDK	452		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...KMQDK	452		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KMQDK	452		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)