Q13557: Calcium/calmodulin-dependent protein kinase type II subunit delta

General Information

Protein names	- Calcium/calmodulin-dependent protein kinase type II subunit delta - CaM kinase II subunit delta - CaMK-II subunit delta - 2.7.11.17
Gene names	CAMK2D
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13557

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform Delta 3 of Calcium/calmodulin-dependent protein kinase type II subunit delta - Isoform Delta 4 of Calcium/calmodulin-dependent protein kinase type II subunit delta - Isoform Delta 6 of Calcium/calmodulin-dependent protein kinase type II subunit delta - Isoform Delta 7 of Calcium/calmodulin-dependent protein kinase type II subunit delta - Isoform Delta 8 of Calcium/calmodulin-dependent protein kinase type II subunit delta - Isoform Delta 9 of Calcium/calmodulin-dependent protein kinase type II subunit delta - Isoform Delta 10 of Calcium/calmodulin-dependent protein kinase type II subunit delta - Isoform Delta 11 of Calcium/calmodulin-dependent protein kinase type II subunit delta - Isoform Delta 12 of Calcium/calmodulin-dependent protein kinase type II subunit delta

Sequence View

        10         20         30         40         50         60
MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER
        70         80         90        100        110        120
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI
       130        140        150        160        170        180
LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY
       190        200        210        220        230        240
LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT
       250        260        270        280        290        300
VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL
       310        320        330        340        350        360
KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA
       370        380        390        400        410        420
INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH
       430        440        450        460        470        480
LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPP
       490
CIPNGKENFS GGTSLWQNI         10         20         30         40         50         60
MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER
        70         80         90        100        110        120
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI
       130        140        150        160        170        180
LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY
       190        200        210        220        230        240
LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT
       250        260        270        280        290        300
VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL
       310        320        330        340        350        360
KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA
       370        380        390        400        410        420
INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH
       430        440        450        460        470        480
LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPP
       490
CIPNGKENFS GGTSLWQNI         10         20         30         40         50         60
MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER
        70         80         90        100        110        120
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI
       130        140        150        160        170        180
LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY
       190        200        210        220        230        240
LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT
       250        260        270        280        290        300
VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL
       310        320        330        340        350        360
KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA
       370        380        390        400        410        420
INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH
       430        440        450        460        470        480
LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPP
       490
CIPNGKENFS GGTSLWQNI         10         20         30         40         50         60
MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER
        70         80         90        100        110        120
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI
       130        140        150        160        170        180
LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY
       190        200        210        220        230        240
LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT
       250        260        270        280        290        300
VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL
       310        320        330        340        350        360
KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA
       370        380        390        400        410        420
INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH
       430        440        450        460        470        480
LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPP
       490
CIPNGKENFS GGTSLWQNI         10         20         30         40         50         60
MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER
        70         80         90        100        110        120
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI
       130        140        150        160        170        180
LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY
       190        200        210        220        230        240
LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT
       250        260        270        280        290        300
VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL
       310        320        330        340        350        360
KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA
       370        380        390        400        410        420
INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH
       430        440        450        460        470        480
LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPP
       490
CIPNGKENFS GGTSLWQNI         10         20         30         40         50         60
MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER
        70         80         90        100        110        120
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI
       130        140        150        160        170        180
LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY
       190        200        210        220        230        240
LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT
       250        260        270        280        290        300
VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL
       310        320        330        340        350        360
KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA
       370        380        390        400        410        420
INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH
       430        440        450        460        470        480
LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPP
       490
CIPNGKENFS GGTSLWQNI         10         20         30         40         50         60
MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER
        70         80         90        100        110        120
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI
       130        140        150        160        170        180
LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY
       190        200        210        220        230        240
LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT
       250        260        270        280        290        300
VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL
       310        320        330        340        350        360
KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA
       370        380        390        400        410        420
INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH
       430        440        450        460        470        480
LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPP
       490
CIPNGKENFS GGTSLWQNI         10         20         30         40         50         60
MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER
        70         80         90        100        110        120
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI
       130        140        150        160        170        180
LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY
       190        200        210        220        230        240
LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT
       250        260        270        280        290        300
VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL
       310        320        330        340        350        360
KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA
       370        380        390        400        410        420
INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH
       430        440        450        460        470        480
LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPP
       490
CIPNGKENFS GGTSLWQNI         10         20         30         40         50         60
MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER
        70         80         90        100        110        120
EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI
       130        140        150        160        170        180
LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY
       190        200        210        220        230        240
LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT
       250        260        270        280        290        300
VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL
       310        320        330        340        350        360
KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA
       370        380        390        400        410        420
INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH
       430        440        450        460        470        480
LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPP
       490
CIPNGKENFS GGTSLWQNI

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13557-1-unknown	MASTTT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78656
Q13557-1-unknown	MASTTT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78657
Q13557-1-unknown	MASTTT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78658
Q13557-1-unknown	MASTTT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78659
Q13557-1-unknown	MASTTT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78660
Q13557-1-unknown	MASTTT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78661
Q13557-2-unknown	MASTTT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13557-2-Acetylation	ASTTTC...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13557-2-Acetylation	ASTTTC...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q13557-2-Acetylation	ASTTTC...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111299
Q13557-2-Acetylation	ASTTTC...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111300
Q13557-2-Acetylation	ASTTTC...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111301
Q13557-2-Acetylation	ASTTTC...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111302
Q13557-2-Acetylation	ASTTTC...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111303
Q13557-2-Acetylation	ASTTTC...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111304

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TVPIKP	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74276
...TVPIKP	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74277
...TVPIKP	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74278
...TVPIKP	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92885
...TVPIKP	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92883
...TVPIKP	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92884
...LWQNI	499	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LWQNI	499	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74274
...LWQNI	499	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74279
...LWQNI	499	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74275

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)