Q13639: 5-hydroxytryptamine receptor 4

General Information

Protein names	- 5-hydroxytryptamine receptor 4 - 5-HT-4 - 5-HT4 - Serotonin receptor 4
Gene names	HTR4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13639

1 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 5-HT4(A) of 5-hydroxytryptamine receptor 4 - Isoform 5-HT4(C) of 5-hydroxytryptamine receptor 4 - Isoform 5-HT4(D) of 5-hydroxytryptamine receptor 4 - Isoform 5-HT4(E) of 5-hydroxytryptamine receptor 4 - Isoform 5-HT4(F) of 5-hydroxytryptamine receptor 4 - Isoform 5-HT4(G) of 5-hydroxytryptamine receptor 4 - Isoform 5-HT4(I) of 5-hydroxytryptamine receptor 4 - Isoform 5-HT4c1 of 5-hydroxytryptamine receptor 4

Sequence View

        10         20         30         40         50         60
MDKLDANVSS EEGFGSVEKV VLLTFLSTVI LMAILGNLLV MVAVCWDRQL RKIKTNYFIV
        70         80         90        100        110        120
SLAFADLLVS VLVMPFGAIE LVQDIWIYGE VFCLVRTSLD VLLTTASIFH LCCISLDRYY
       130        140        150        160        170        180
AICCQPLVYR NKMTPLRIAL MLGGCWVIPT FISFLPIMQG WNNIGIIDLI EKRKFNQNSN
       190        200        210        220        230        240
STYCVFMVNK PYAITCSVVA FYIPFLLMVL AYYRIYVTAK EHAHQIQMLQ RAGASSESRP
       250        260        270        280        290        300
QSADQHSTHR MRTETKAAKT LCIIMGCFCL CWAPFFVTNI VDPFIDYTVP GQVWTAFLWL
       310        320        330        340        350        360
GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYRRPSIL GQTVPCSTTT INGSTHVLRD
       370        380
AVECGGQWES QCHPPATSPL VAAQPSDT         10         20         30         40         50         60
MDKLDANVSS EEGFGSVEKV VLLTFLSTVI LMAILGNLLV MVAVCWDRQL RKIKTNYFIV
        70         80         90        100        110        120
SLAFADLLVS VLVMPFGAIE LVQDIWIYGE VFCLVRTSLD VLLTTASIFH LCCISLDRYY
       130        140        150        160        170        180
AICCQPLVYR NKMTPLRIAL MLGGCWVIPT FISFLPIMQG WNNIGIIDLI EKRKFNQNSN
       190        200        210        220        230        240
STYCVFMVNK PYAITCSVVA FYIPFLLMVL AYYRIYVTAK EHAHQIQMLQ RAGASSESRP
       250        260        270        280        290        300
QSADQHSTHR MRTETKAAKT LCIIMGCFCL CWAPFFVTNI VDPFIDYTVP GQVWTAFLWL
       310        320        330        340        350        360
GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYRRPSIL GQTVPCSTTT INGSTHVLRD
       370        380
AVECGGQWES QCHPPATSPL VAAQPSDT         10         20         30         40         50         60
MDKLDANVSS EEGFGSVEKV VLLTFLSTVI LMAILGNLLV MVAVCWDRQL RKIKTNYFIV
        70         80         90        100        110        120
SLAFADLLVS VLVMPFGAIE LVQDIWIYGE VFCLVRTSLD VLLTTASIFH LCCISLDRYY
       130        140        150        160        170        180
AICCQPLVYR NKMTPLRIAL MLGGCWVIPT FISFLPIMQG WNNIGIIDLI EKRKFNQNSN
       190        200        210        220        230        240
STYCVFMVNK PYAITCSVVA FYIPFLLMVL AYYRIYVTAK EHAHQIQMLQ RAGASSESRP
       250        260        270        280        290        300
QSADQHSTHR MRTETKAAKT LCIIMGCFCL CWAPFFVTNI VDPFIDYTVP GQVWTAFLWL
       310        320        330        340        350        360
GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYRRPSIL GQTVPCSTTT INGSTHVLRD
       370        380
AVECGGQWES QCHPPATSPL VAAQPSDT         10         20         30         40         50         60
MDKLDANVSS EEGFGSVEKV VLLTFLSTVI LMAILGNLLV MVAVCWDRQL RKIKTNYFIV
        70         80         90        100        110        120
SLAFADLLVS VLVMPFGAIE LVQDIWIYGE VFCLVRTSLD VLLTTASIFH LCCISLDRYY
       130        140        150        160        170        180
AICCQPLVYR NKMTPLRIAL MLGGCWVIPT FISFLPIMQG WNNIGIIDLI EKRKFNQNSN
       190        200        210        220        230        240
STYCVFMVNK PYAITCSVVA FYIPFLLMVL AYYRIYVTAK EHAHQIQMLQ RAGASSESRP
       250        260        270        280        290        300
QSADQHSTHR MRTETKAAKT LCIIMGCFCL CWAPFFVTNI VDPFIDYTVP GQVWTAFLWL
       310        320        330        340        350        360
GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYRRPSIL GQTVPCSTTT INGSTHVLRD
       370        380
AVECGGQWES QCHPPATSPL VAAQPSDT         10         20         30         40         50         60
MDKLDANVSS EEGFGSVEKV VLLTFLSTVI LMAILGNLLV MVAVCWDRQL RKIKTNYFIV
        70         80         90        100        110        120
SLAFADLLVS VLVMPFGAIE LVQDIWIYGE VFCLVRTSLD VLLTTASIFH LCCISLDRYY
       130        140        150        160        170        180
AICCQPLVYR NKMTPLRIAL MLGGCWVIPT FISFLPIMQG WNNIGIIDLI EKRKFNQNSN
       190        200        210        220        230        240
STYCVFMVNK PYAITCSVVA FYIPFLLMVL AYYRIYVTAK EHAHQIQMLQ RAGASSESRP
       250        260        270        280        290        300
QSADQHSTHR MRTETKAAKT LCIIMGCFCL CWAPFFVTNI VDPFIDYTVP GQVWTAFLWL
       310        320        330        340        350        360
GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYRRPSIL GQTVPCSTTT INGSTHVLRD
       370        380
AVECGGQWES QCHPPATSPL VAAQPSDT         10         20         30         40         50         60
MDKLDANVSS EEGFGSVEKV VLLTFLSTVI LMAILGNLLV MVAVCWDRQL RKIKTNYFIV
        70         80         90        100        110        120
SLAFADLLVS VLVMPFGAIE LVQDIWIYGE VFCLVRTSLD VLLTTASIFH LCCISLDRYY
       130        140        150        160        170        180
AICCQPLVYR NKMTPLRIAL MLGGCWVIPT FISFLPIMQG WNNIGIIDLI EKRKFNQNSN
       190        200        210        220        230        240
STYCVFMVNK PYAITCSVVA FYIPFLLMVL AYYRIYVTAK EHAHQIQMLQ RAGASSESRP
       250        260        270        280        290        300
QSADQHSTHR MRTETKAAKT LCIIMGCFCL CWAPFFVTNI VDPFIDYTVP GQVWTAFLWL
       310        320        330        340        350        360
GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYRRPSIL GQTVPCSTTT INGSTHVLRD
       370        380
AVECGGQWES QCHPPATSPL VAAQPSDT         10         20         30         40         50         60
MDKLDANVSS EEGFGSVEKV VLLTFLSTVI LMAILGNLLV MVAVCWDRQL RKIKTNYFIV
        70         80         90        100        110        120
SLAFADLLVS VLVMPFGAIE LVQDIWIYGE VFCLVRTSLD VLLTTASIFH LCCISLDRYY
       130        140        150        160        170        180
AICCQPLVYR NKMTPLRIAL MLGGCWVIPT FISFLPIMQG WNNIGIIDLI EKRKFNQNSN
       190        200        210        220        230        240
STYCVFMVNK PYAITCSVVA FYIPFLLMVL AYYRIYVTAK EHAHQIQMLQ RAGASSESRP
       250        260        270        280        290        300
QSADQHSTHR MRTETKAAKT LCIIMGCFCL CWAPFFVTNI VDPFIDYTVP GQVWTAFLWL
       310        320        330        340        350        360
GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYRRPSIL GQTVPCSTTT INGSTHVLRD
       370        380
AVECGGQWES QCHPPATSPL VAAQPSDT         10         20         30         40         50         60
MDKLDANVSS EEGFGSVEKV VLLTFLSTVI LMAILGNLLV MVAVCWDRQL RKIKTNYFIV
        70         80         90        100        110        120
SLAFADLLVS VLVMPFGAIE LVQDIWIYGE VFCLVRTSLD VLLTTASIFH LCCISLDRYY
       130        140        150        160        170        180
AICCQPLVYR NKMTPLRIAL MLGGCWVIPT FISFLPIMQG WNNIGIIDLI EKRKFNQNSN
       190        200        210        220        230        240
STYCVFMVNK PYAITCSVVA FYIPFLLMVL AYYRIYVTAK EHAHQIQMLQ RAGASSESRP
       250        260        270        280        290        300
QSADQHSTHR MRTETKAAKT LCIIMGCFCL CWAPFFVTNI VDPFIDYTVP GQVWTAFLWL
       310        320        330        340        350        360
GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYRRPSIL GQTVPCSTTT INGSTHVLRD
       370        380
AVECGGQWES QCHPPATSPL VAAQPSDT

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q13639-1-unknown	MDKLDA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q13639-1-unknown	MDKLDA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65804
Q13639-1-unknown	MDKLDA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65805
Q13639-1-unknown	MDKLDA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65806
Q13639-1-unknown	MDKLDA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65807
Q13639-1-unknown	MDKLDA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65808
Q13639-1-unknown	MDKLDA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65809
Q13639-1-unknown	MDKLDA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65810
Q13639-1-unknown	MDKLDA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65811

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...THVLRD	359	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61427
...THVLRD	359	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92520
...THVLRD	359	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92522
...THVLRD	359	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92523
...THVLRD	359	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92521
...QPSDT	388	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QPSDT	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61426
...QPSDT	388	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61428

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)