Q13769: THO complex subunit 5 homolog

General Information

Protein names	- THO complex subunit 5 homolog - Functional spliceosome-associated protein 79 - fSAP79 - NF2/meningioma region protein pK1.3 - Placental protein 39.2 - PP39.2 - hTREX90
Gene names	THOC5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13769

3 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSSESSKKRK PKVIRSDGAP AEGKRNRSDT EQEGKYYSEE AEVDLRDPGR DYELYKYTCQ
        70         80         90        100        110        120
ELQRLMAEIQ DLKSRGGKDV AIEIEERRIQ SCVHFMTLKK LNRLAHIRLK KGRDQTHEAK
       130        140        150        160        170        180
QKVDAYHLQL QNLLYEVMHL QKEITKCLEF KSKHEEIDLV SLEEFYKEAP PDISKAEVTM
       190        200        210        220        230        240
GDPHQQTLAR LDWELEQRKR LAEKYRECLS NKEKILKEIE VKKEYLSSLQ PRLNSIMQAS
       250        260        270        280        290        300
LPVQEYLFMP FDQAHKQYET ARHLPPPLYV LFVQATAYGQ ACDKTLSVAI EGSVDEAKAL
       310        320        330        340        350        360
FKPPEDSQDD ESDSDAEEEQ TTKRRRPTLG VQLDDKRKEM LKRHPLSVML DLKCKDDSVL
       370        380        390        400        410        420
HLTFYYLMNL NIMTVKAKVT TAMELITPIS AGDLLSPDSV LSCLYPGDHG KKTPNPANQY
       430        440        450        460        470        480
QFDKVGILTL SDYVLELGHP YLWVQKLGGL HFPKEQPQQT VIADHSLSAS HMETTMKLLK
       490        500        510        520        530        540
TRVQSRLALH KQFASLEHGI VPVTSDCQYL FPAKVVSRLV KWVTVAHEDY MELHFTKDIV
       550        560        570        580        590        600
DAGLAGDTNL YYMALIERGT AKLQAAVVLN PGYSSIPPVF QLCLNWKGEK TNSNDDNIRA
       610        620        630        640        650        660
MEGEVNVCYK ELCGPWPSHQ LLTNQLQRLC VLLDVYLETE SHDDSVEGPK EFPQEKMCLR
       670        680
LFRGPSRMKP FKYNHPQGFF SHR

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

3 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13769-1-acetylation	MSSESS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q13769-2-unknown	MSSESS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13769-2-Acetylation	SSESSK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13769-2-Acetylation	SSESSK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q13769-2-Acetylation	SSESSK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IQSCVH	93	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000388039
...IDLVSL	161	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000416804
...WELEQR	197	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415425
...IEVKKE	223	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000413505
...TPISAG	391	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000393247
...FFSHR	683	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)