TopFIND 4.0

Q13868: Exosome complex component RRP4 {ECO:0000305}

General Information

Protein names
- Exosome complex component RRP4 {ECO:0000305}
- Exosome component 2
- Ribosomal RNA-processing protein 4
Gene names EXOSC2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q13868

1

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAMEMRLPVA RKPLSERLGR DTKKHLVVPG DTITTDTGFM RGHGTYMGEE KLIASVAGSV 
        70         80         90        100        110        120 
ERVNKLICVK ALKTRYIGEV GDIVVGRITE VQQKRWKVET NSRLDSVLLL SSMNLPGGEL 
       130        140        150        160        170        180 
RRRSAEDELA MRGFLQEGDL ISAEVQAVFS DGAVSLHTRS LKYGKLGQGV LVQVSPSLVK 
       190        200        210        220        230        240 
RQKTHFHDLP CGASVILGNN GFIWIYPTPE HKEEEAGGFI ANLEPVSLAD REVISRLRNC 
       250        260        270        280        290    
IISLVTQRMM LYDTSILYCY EASLPHQIKD ILKPEIMEEI VMETRQRLLE QEG

Isoforms

- Isoform 2 of Exosome complex component RRP4 - Isoform 3 of Exosome complex component RRP4

Sequence View

        10         20         30         40         50         60 
MAMEMRLPVA RKPLSERLGR DTKKHLVVPG DTITTDTGFM RGHGTYMGEE KLIASVAGSV 
        70         80         90        100        110        120 
ERVNKLICVK ALKTRYIGEV GDIVVGRITE VQQKRWKVET NSRLDSVLLL SSMNLPGGEL 
       130        140        150        160        170        180 
RRRSAEDELA MRGFLQEGDL ISAEVQAVFS DGAVSLHTRS LKYGKLGQGV LVQVSPSLVK 
       190        200        210        220        230        240 
RQKTHFHDLP CGASVILGNN GFIWIYPTPE HKEEEAGGFI ANLEPVSLAD REVISRLRNC 
       250        260        270        280        290    
IISLVTQRMM LYDTSILYCY EASLPHQIKD ILKPEIMEEI VMETRQRLLE QEG         10         20         30         40         50         60 
MAMEMRLPVA RKPLSERLGR DTKKHLVVPG DTITTDTGFM RGHGTYMGEE KLIASVAGSV 
        70         80         90        100        110        120 
ERVNKLICVK ALKTRYIGEV GDIVVGRITE VQQKRWKVET NSRLDSVLLL SSMNLPGGEL 
       130        140        150        160        170        180 
RRRSAEDELA MRGFLQEGDL ISAEVQAVFS DGAVSLHTRS LKYGKLGQGV LVQVSPSLVK 
       190        200        210        220        230        240 
RQKTHFHDLP CGASVILGNN GFIWIYPTPE HKEEEAGGFI ANLEPVSLAD REVISRLRNC 
       250        260        270        280        290    
IISLVTQRMM LYDTSILYCY EASLPHQIKD ILKPEIMEEI VMETRQRLLE QEG



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Protein Neighborhood

Domains & Features

1 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q13868-1-unknown MAMEMR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q13868-1-unknown MAMEMR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74327

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)