Q14159: DNA repair-scaffolding protein

General Information

Protein names	- DNA repair-scaffolding protein - Scaffolding protein involved in DNA repair
Gene names	SPIDR
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14159

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of DNA repair-scaffolding protein - Isoform 3 of DNA repair-scaffolding protein

Sequence View

        10         20         30         40         50         60
MPRGSRARGS KRKRSWNTEC PSFPGERPLQ VRRAGLRTAG AAASLSEAWL RCGEGFQNTS
        70         80         90        100        110        120
GNPSLTAEEK TITEKHLELC PRPKQETTTS KSTSGLTDIT WSSSGSDLSD EDKTLSQLQR
       130        140        150        160        170        180
DELQFIDWEI DSDRAEASDC DEFEDDEGAV EISDCASCAS NQSLTSDEKL SELPKPSSIE
       190        200        210        220        230        240
ILEYSSDSEK EDDLENVLLI DSESPHKYHV QFASDARQIM ERLIDPRTKS TETILHTPQK
       250        260        270        280        290        300
PTAKFPRTPE NSAKKKLLRG GLAERLNGLQ NRERSAISLW RHQCISYQKT LSGRKSGVLT
       310        320        330        340        350        360
VKILELHEEC AMQVAMCEQL LGSPATSSSQ SVAPRPGAGL KVLFTKETAG YLRGRPQDTV
       370        380        390        400        410        420
RIFPPWQKLI IPSGSCPVIL NTYFCEKVVA KEDSEKTCEV YCPDIPLPRR SISLAQMFVI
       430        440        450        460        470        480
KGLTNNSPEI QVVCSGVATT GTAWTHGHKE AKQRIPTSTP LRDSLLDVVE SQGAASWPGA
       490        500        510        520        530        540
GVRVVVQRVY SLPSRDSTRG QQGASSGHTD PAGTRACLLV QDACGMFGEV HLEFTMSKAR
       550        560        570        580        590        600
QLEGKSCSLV GMKVLQKVTR GRTAGIFSLI DTLWPPAIPL KTPGRDQPCE EIKTHLPPPA
       610        620        630        640        650        660
LCYILTAHPN LGQIDIIDED PIYKLYQPPV TRCLRDILQM NDLGTRCSFY ATVIYQKPQL
       670        680        690        700        710        720
KSLLLLEQRE IWLLVTDVTL QTKEERDPRL PKTLLVYVAP LCVLGSEVLE ALAGAAPHSL
       730        740        750        760        770        780
FFKDALRDQG RIVCAERTVL LLQKPLLSVV SGASSCELPG PVMLDSLDSA TPVNSICSVQ
       790        800        810        820        830        840
GTVVGVDEST AFSWPVCDMC GNGRLEQRPE DRGAFSCGDC SRVVTSPVLK RHLQVFLDCR
       850        860        870        880        890        900
SRPQCRVKVK LLQRSISSLL RFAAGEDGSY EVKSVLGKEV GLLNCFVQSV TAHPTSCIGL
       910
EEIELLSAGG ASAEH         10         20         30         40         50         60
MPRGSRARGS KRKRSWNTEC PSFPGERPLQ VRRAGLRTAG AAASLSEAWL RCGEGFQNTS
        70         80         90        100        110        120
GNPSLTAEEK TITEKHLELC PRPKQETTTS KSTSGLTDIT WSSSGSDLSD EDKTLSQLQR
       130        140        150        160        170        180
DELQFIDWEI DSDRAEASDC DEFEDDEGAV EISDCASCAS NQSLTSDEKL SELPKPSSIE
       190        200        210        220        230        240
ILEYSSDSEK EDDLENVLLI DSESPHKYHV QFASDARQIM ERLIDPRTKS TETILHTPQK
       250        260        270        280        290        300
PTAKFPRTPE NSAKKKLLRG GLAERLNGLQ NRERSAISLW RHQCISYQKT LSGRKSGVLT
       310        320        330        340        350        360
VKILELHEEC AMQVAMCEQL LGSPATSSSQ SVAPRPGAGL KVLFTKETAG YLRGRPQDTV
       370        380        390        400        410        420
RIFPPWQKLI IPSGSCPVIL NTYFCEKVVA KEDSEKTCEV YCPDIPLPRR SISLAQMFVI
       430        440        450        460        470        480
KGLTNNSPEI QVVCSGVATT GTAWTHGHKE AKQRIPTSTP LRDSLLDVVE SQGAASWPGA
       490        500        510        520        530        540
GVRVVVQRVY SLPSRDSTRG QQGASSGHTD PAGTRACLLV QDACGMFGEV HLEFTMSKAR
       550        560        570        580        590        600
QLEGKSCSLV GMKVLQKVTR GRTAGIFSLI DTLWPPAIPL KTPGRDQPCE EIKTHLPPPA
       610        620        630        640        650        660
LCYILTAHPN LGQIDIIDED PIYKLYQPPV TRCLRDILQM NDLGTRCSFY ATVIYQKPQL
       670        680        690        700        710        720
KSLLLLEQRE IWLLVTDVTL QTKEERDPRL PKTLLVYVAP LCVLGSEVLE ALAGAAPHSL
       730        740        750        760        770        780
FFKDALRDQG RIVCAERTVL LLQKPLLSVV SGASSCELPG PVMLDSLDSA TPVNSICSVQ
       790        800        810        820        830        840
GTVVGVDEST AFSWPVCDMC GNGRLEQRPE DRGAFSCGDC SRVVTSPVLK RHLQVFLDCR
       850        860        870        880        890        900
SRPQCRVKVK LLQRSISSLL RFAAGEDGSY EVKSVLGKEV GLLNCFVQSV TAHPTSCIGL
       910
EEIELLSAGG ASAEH

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q14159-1-unknown	MPRGSR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q14159-312-unknown	MQVAMC...	312	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000476515
Q14159-312-unknown	MQVAMC...	312	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000430091
Q14159-526-unknown	MFGEVH...	526	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000476729
Q14159-526-unknown	MFGEVH...	526	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000427889
Q14159-799-unknown	MCGNGR...	799	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000477202
Q14159-799-unknown	MCGNGR...	799	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000476475
Q14159-799-unknown	MCGNGR...	799	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000427878
Q14159-799-unknown	MCGNGR...	799	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000429448

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TPLRDS	463	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000476515
...TPLRDS	463	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000430091
...FVQSVT	890	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000477202
...FVQSVT	890	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000427878
...ASAEH	915	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)