Q14642: Inositol polyphosphate-5-phosphatase A

General Information

Protein names	- Inositol polyphosphate-5-phosphatase A - 3.1.3.56 {ECO:0000269\|PubMed:8013665, ECO:0000269\|PubMed:8769125} - 43 kDa inositol polyphosphate 5-phosphatase {ECO:0000303\|PubMed:8006039} - Type I inositol 1,4,5-trisphosphate 5-phosphatase {ECO:0000303\|PubMed:8013665} - 5PTase {ECO:0000303\|PubMed:8013665}
Gene names	INPP5A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14642

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGKAAAPGT AVLLVTANVG SLFDDPENLQ KNWLREFYQV VHTHKPHFMA LHCQEFGGKN
        70         80         90        100        110        120
YEASMSHVDK FVKELLSSDA MKEYNRARVY LDENYKSQEH FTALGSFYFL HESLKNIYQF
       130        140        150        160        170        180
DFKAKKYRKV AGKEIYSDTL ESTPMLEKEK FPQDYFPECK WSRKGFIRTR WCIADCAFDL
       190        200        210        220        230        240
VNIHLFHDAS NLVAWETSPS VYSGIRHKAL GYVLDRIIDQ RFEKVSYFVF GDFNFRLDSK
       250        260        270        280        290        300
SVVETLCTKA TMQTVRAADT NEVVKLIFRE SDNDRKVMLQ LEKKLFDYFN QEVFRDNNGT
       310        320        330        340        350        360
ALLEFDKELS VFKDRLYELD ISFPPSYPYS EDARQGEQYM NTRCPAWCDR ILMSPSAKEL
       370        380        390        400        410
VLRSESEEKV VTYDHIGPNV CMGDHKPVFL AFRIMPGAGK PHAHVHKCCV VQ

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q14642-1-unknown	MAGKAA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q14642-15-unknown	VTANVG...	15	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390936
Q14642-319-unknown	LDISFP...	319	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390749

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GYVLDR	215	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390936
...ELVLRS	363	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000340707
...VHKCCV	409	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)