Q14764: Major vault protein

General Information

Protein names	- Major vault protein - MVP - Lung resistance-related protein
Gene names	MVP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14764

2 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATEEFIIRI PPYHYIHVLD QNSNVSRVEV GPKTYIRQDN ERVLFAPMRM VTVPPRHYCT
        70         80         90        100        110        120
VANPVSRDAQ GLVLFDVTGQ VRLRHADLEI RLAQDPFPLY PGEVLEKDIT PLQVVLPNTA
       130        140        150        160        170        180
LHLKALLDFE DKDGDKVVAG DEWLFEGPGT YIPRKEVEVV EIIQATIIRQ NQALRLRARK
       190        200        210        220        230        240
ECWDRDGKER VTGEEWLVTT VGAYLPAVFE EVLDLVDAVI LTEKTALHLR ARRNFRDFRG
       250        260        270        280        290        300
VSRRTGEEWL VTVQDTEAHV PDVHEEVLGV VPITTLGPHN YCVILDPVGP DGKNQLGQKR
       310        320        330        340        350        360
VVKGEKSFFL QPGEQLEQGI QDVYVLSEQQ GLLLRALQPL EEGEDEEKVS HQAGDHWLIR
       370        380        390        400        410        420
GPLEYVPSAK VEVVEERQAI PLDENEGIYV QDVKTGKVRA VIGSTYMLTQ DEVLWEKELP
       430        440        450        460        470        480
PGVEELLNKG QDPLADRGEK DTAKSLQPLA PRNKTRVVSY RVPHNAAVQV YDYREKRARV
       490        500        510        520        530        540
VFGPELVSLG PEEQFTVLSL SAGRPKRPHA RRALCLLLGP DFFTDVITIE TADHARLQLQ
       550        560        570        580        590        600
LAYNWHFEVN DRKDPQETAK LFSVPDFVGD ACKAIASRVR GAVASVTFDD FHKNSARIIR
       610        620        630        640        650        660
TAVFGFETSE AKGPDGMALP RPRDQAVFPQ NGLVVSSVDV QSVEPVDQRT RDALQRSVQL
       670        680        690        700        710        720
AIEITTNSQE AAAKHEAQRL EQEARGRLER QKILDQSEAE KARKELLELE ALSMAVESTG
       730        740        750        760        770        780
TAKAEAESRA EAARIEGEGS VLQAKLKAQA LAIETEAELQ RVQKVRELEL VYARAQLELE
       790        800        810        820        830        840
VSKAQQLAEV EVKKFKQMTE AIGPSTIRDL AVAGPEMQVK LLQSLGLKST LITDGSTPIN
       850        860        870        880        890
LFNTAFGLLG MGPEGQPLGR RVASGPSPGE GISPQSAQAP QAPGDNHVVP VLR

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q14764-2-unknown	MATEEF...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14764-2-Acetylation	ATEEFI...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14764-2-Acetylation	ATEEFI...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q14764-2-Acetylation	ATEEFI...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QDNERV	42	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454819
...IRLAQD	94	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455186
...EVLEKD	107	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457685
...LFEGPG	148	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456291
...VDAVIL	220	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455819
...DEVLWE	415	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454825
...VPVLR	893	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)