TopFIND 4.0

Q14B46: Rhotekin-2

General Information

Protein names
- Rhotekin-2
- Pleckstrin homology domain-containing family K member 1
- PH domain-containing family K member 1
Gene names Rtkn2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q14B46

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEGQLLRGLA AQQDCSIREK IDLEIRMREG IWKLLSLSTK KDQVLHAVKN LMVCSARIQA 
        70         80         90        100        110        120 
YTAELQKSKE EIANQTGARL VLDSSSENKE GESCRGKIAL SDIRIPLMWK DSDHFSNKEC 
       130        140        150        160        170        180 
TQRFAIFCLF RMGAQVFDTD MVIVDQTVTD ICFENVTIFN EAGPDFQIKI EVYSCSAEES 
       190        200        210        220        230        240 
SLTNTPRKLA KKLKTSISKA TGRKISAALQ EESPEACLLA GSVAGAKYHL LAHTTLTLEN 
       250        260        270        280        290        300 
AGDCFKTHNL SVHGDEECSF WLPLYGNVCC RLVAQPACMA ADAFAGFLNE QQTGKGLVGW 
       310        320        330        340        350        360 
RRLYCALRGG KLRCFYGPEE IEAKVEPALV VPIDKETRIQ AVEKDSKKMH CFSVLSTAAG 
       370        380        390        400        410        420 
RAVSHIFAAD SLADFQEWMG AFRQHFFDLS QWKHCCEELM RIEIMSPRKP PLFLAKEATS 
       430        440        450        460        470        480 
VYYDMSIDSP VKLESVTDII QKKIGETNRQ FLIGRDDQSA APPWAAVFDG NHEMVIEKKV 
       490        500        510        520        530        540 
LSPIGEPAPD GKRKKRRAPL PPTDQPPFCI KTQGRANQSK DSATQAGVSG ASSSPSDPRL 
       550        560        570        580        590        600 
SPPTHHLQKP VAAPRKLLPA RKNSSADIGH TDTKTSLDAK PVPVPRQKSI RDILDPRSWL 
   
QAQV

Isoforms

- Isoform 2 of Rhotekin-2

Sequence View

        10         20         30         40         50         60 
MEGQLLRGLA AQQDCSIREK IDLEIRMREG IWKLLSLSTK KDQVLHAVKN LMVCSARIQA 
        70         80         90        100        110        120 
YTAELQKSKE EIANQTGARL VLDSSSENKE GESCRGKIAL SDIRIPLMWK DSDHFSNKEC 
       130        140        150        160        170        180 
TQRFAIFCLF RMGAQVFDTD MVIVDQTVTD ICFENVTIFN EAGPDFQIKI EVYSCSAEES 
       190        200        210        220        230        240 
SLTNTPRKLA KKLKTSISKA TGRKISAALQ EESPEACLLA GSVAGAKYHL LAHTTLTLEN 
       250        260        270        280        290        300 
AGDCFKTHNL SVHGDEECSF WLPLYGNVCC RLVAQPACMA ADAFAGFLNE QQTGKGLVGW 
       310        320        330        340        350        360 
RRLYCALRGG KLRCFYGPEE IEAKVEPALV VPIDKETRIQ AVEKDSKKMH CFSVLSTAAG 
       370        380        390        400        410        420 
RAVSHIFAAD SLADFQEWMG AFRQHFFDLS QWKHCCEELM RIEIMSPRKP PLFLAKEATS 
       430        440        450        460        470        480 
VYYDMSIDSP VKLESVTDII QKKIGETNRQ FLIGRDDQSA APPWAAVFDG NHEMVIEKKV 
       490        500        510        520        530        540 
LSPIGEPAPD GKRKKRRAPL PPTDQPPFCI KTQGRANQSK DSATQAGVSG ASSSPSDPRL 
       550        560        570        580        590        600 
SPPTHHLQKP VAAPRKLLPA RKNSSADIGH TDTKTSLDAK PVPVPRQKSI RDILDPRSWL 
   
QAQV



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q14B46-1-unknown MEGQLL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q14B46-1-unknown MEGQLL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88331

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LQAQV 604 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LQAQV 604 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt83949

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)