TopFIND 4.0

Q14CN4: Keratin, type II cytoskeletal 72

General Information

Protein names
- Keratin, type II cytoskeletal 72
- Cytokeratin-72
- CK-72
- Keratin-72
- K72
- Type II inner root sheath-specific keratin-K6irs2
- Type-II keratin Kb35
Gene names KRT72
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q14CN4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSRQLTHFPR GERLGFSGCS AVLSGGIGSS SASFRARVKG SASFGSKSLS CLGGSRSLAL 
        70         80         90        100        110        120 
SAAARRGGGR LGGFVGTAFG SAGLGPKCPS VCPPGGIPQV TVNKSLLAPL NVEMDPEIQR 
       130        140        150        160        170        180 
VRAQEREQIK ALNNKFASFI DKVRFLEQQN QVLETKWNLL QQLDLNNCRK NLEPIYEGYI 
       190        200        210        220        230        240 
SNLQKQLEML SGDGVRLDSE LRNMQDLVED YKKRYEVEIN RRTAAENEFV VLKKDVDAAY 
       250        260        270        280        290        300 
MNKVELQAKV DSLTDEIKFF KCLYEGEITQ IQSHISDTSI VLSMDNNRDL DLDSIIAEVR 
       310        320        330        340        350        360 
AQYEEIALKS KAEAETLYQT KIQELQVTAG QHGDDLKLTK AEISELNRLI QRIRSEIGNV 
       370        380        390        400        410        420 
KKQCADLETA IADAEQRGDC ALKDARAKLD ELEGALHQAK EELARMLREY QELVSLKLAL 
       430        440        450        460        470        480 
DMEIATYRKL LESEECRMSG EYPNSVSISV ISSTNAGAGG AGFSMGFGAS SSYSYKTAAA 
       490        500        510    
DVKTKGSCGS ELKDPLAKTS GSSCATKKAS R

Isoforms

- Isoform 2 of Keratin, type II cytoskeletal 72 - Isoform 3 of Keratin, type II cytoskeletal 72

Sequence View

        10         20         30         40         50         60 
MSRQLTHFPR GERLGFSGCS AVLSGGIGSS SASFRARVKG SASFGSKSLS CLGGSRSLAL 
        70         80         90        100        110        120 
SAAARRGGGR LGGFVGTAFG SAGLGPKCPS VCPPGGIPQV TVNKSLLAPL NVEMDPEIQR 
       130        140        150        160        170        180 
VRAQEREQIK ALNNKFASFI DKVRFLEQQN QVLETKWNLL QQLDLNNCRK NLEPIYEGYI 
       190        200        210        220        230        240 
SNLQKQLEML SGDGVRLDSE LRNMQDLVED YKKRYEVEIN RRTAAENEFV VLKKDVDAAY 
       250        260        270        280        290        300 
MNKVELQAKV DSLTDEIKFF KCLYEGEITQ IQSHISDTSI VLSMDNNRDL DLDSIIAEVR 
       310        320        330        340        350        360 
AQYEEIALKS KAEAETLYQT KIQELQVTAG QHGDDLKLTK AEISELNRLI QRIRSEIGNV 
       370        380        390        400        410        420 
KKQCADLETA IADAEQRGDC ALKDARAKLD ELEGALHQAK EELARMLREY QELVSLKLAL 
       430        440        450        460        470        480 
DMEIATYRKL LESEECRMSG EYPNSVSISV ISSTNAGAGG AGFSMGFGAS SSYSYKTAAA 
       490        500        510    
DVKTKGSCGS ELKDPLAKTS GSSCATKKAS R         10         20         30         40         50         60 
MSRQLTHFPR GERLGFSGCS AVLSGGIGSS SASFRARVKG SASFGSKSLS CLGGSRSLAL 
        70         80         90        100        110        120 
SAAARRGGGR LGGFVGTAFG SAGLGPKCPS VCPPGGIPQV TVNKSLLAPL NVEMDPEIQR 
       130        140        150        160        170        180 
VRAQEREQIK ALNNKFASFI DKVRFLEQQN QVLETKWNLL QQLDLNNCRK NLEPIYEGYI 
       190        200        210        220        230        240 
SNLQKQLEML SGDGVRLDSE LRNMQDLVED YKKRYEVEIN RRTAAENEFV VLKKDVDAAY 
       250        260        270        280        290        300 
MNKVELQAKV DSLTDEIKFF KCLYEGEITQ IQSHISDTSI VLSMDNNRDL DLDSIIAEVR 
       310        320        330        340        350        360 
AQYEEIALKS KAEAETLYQT KIQELQVTAG QHGDDLKLTK AEISELNRLI QRIRSEIGNV 
       370        380        390        400        410        420 
KKQCADLETA IADAEQRGDC ALKDARAKLD ELEGALHQAK EELARMLREY QELVSLKLAL 
       430        440        450        460        470        480 
DMEIATYRKL LESEECRMSG EYPNSVSISV ISSTNAGAGG AGFSMGFGAS SSYSYKTAAA 
       490        500        510    
DVKTKGSCGS ELKDPLAKTS GSSCATKKAS R



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q14CN4-1-unknown MSRQLT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q14CN4-1-unknown MSRQLT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt78477
    Q14CN4-1-unknown MSRQLT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt78478

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)